CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Fan, Zheng, Devlin, Jennifer R., Hogg, Simon J., Doyle, Maria A., Harrison, Paul F., Todorovski, Izabela, Cluse, Leonie A., Knight, Deborah A. +13 more·2020·Science Advances

DOI 10.1126/sciadv.aaz5041

Cited by (171)

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Additional file 3 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
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Additional file 2 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
Additional file 1 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
Additional file 1 of Internal and external normalization of nascent RNA sequencing run-on experiments
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Additional file 4 of Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids
Eleonora Cesari, Alessandra Ciucci, Marco Pieraccioli, Cinzia Caggiano, Camilla Nero, Davide Bonvissuto, Francesca Sillano, Marianna Buttarelli, Alessia Piermattei, Matteo Loverro et al. · 2024 · Figshare
Additional file 2 of Internal and external normalization of nascent RNA sequencing run-on experiments
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BindingDB Entry 50015218: Noncovalent CDK12/13 dual inhibitors-based PROTACs degrade CDK12-Cyclin K complex and induce synthetic lethality with PARP inhibitor.
BindingDB · 2023 · UC San Diego
BindingDB Entry 50016375: Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13.
BindingDB · 2023 · UC San Diego
BindingDB Entry 50015910: Current progress and novel strategies that target CDK12 for drug discovery.
BindingDB · 2023 · UC San Diego