MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program

Wang, Yi, Zhang, Lei, Wu, Guo-Rao, Zhou, Qing, Yue, Huihui, Rao, Li-Zong, Yuan, Ting, Mo, Biwen, Wang, Fa-Xi, Chen, Long-Min, Sun, Fei, Song, Jia, Xiong, Fei, Zhang, Shu, Yu, Qilin, Yang, Ping, Xu, Yongjian, Zhao, Jianping, Zhang, Huilan, Xiong, Weining, Wang, Cong-Yi·2021·Science Advances

DOI 10.1126/sciadv.abb6075

Cited by (228)

Items 101–200 of 228

Epigenetic Changes and Functions in Pneumoconiosis
Yiping Li, Zhiwei Cheng, Hui Fan, Changfu Hao, Wu Yao · 2022 · Oxidative Medicine and Cellular Longevity
Hydrogen-induced disruption of the airway mucus barrier enhances nebulized RNA delivery to reverse pulmonary fibrosis
Chang Liu, Xidong Tian, Zhenping Wang, Jcw Mak, Shirui Mao, Tzu‐Ming Liu, Ying Zheng · 2025 · Science Advances
Exosome-mediated macrophage polarization: Pioneering pathways in diabetic wound healing
Yi Zheng, Zhichao Ruan, Shuoyuan Liu, Xiaofan Yang, Zhenbing Chen · 2025 · International Immunopharmacology
Exploring reduced macrophage cell toxicity of hypervirulent Klebsiella pneumoniae compared to classical Klebsiella pneumoniae
Sohana Akter Mina, Gaochen Zhu, Maryam Fanian, Sheng Chen, Guan Yang · 2023 · Microbiological Research
Blockade of Mbd2 by siRNA-loaded liposomes protects mice against OVA-induced allergic airway inflammation via repressing M2 macrophage production
Guorao Wu, Min Zhou, Yi Wang, Qing Zhou, Lei Zhang, Long He, Shu Zhang, Qilin Yu, Yongjian Xu, Jianping Zhao et al. · 2022 · Frontiers in Immunology
Epigenetics Approaches toward Precision Medicine for Idiopathic Pulmonary Fibrosis: Focus on DNA Methylation
Wiwin Is Effendi, Tatsuya Nagano · 2023 · Biomedicines
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling
Yiwei Wang, Xingchen Geng, Zhihua Guo, Dandan Chu, Ruixing Liu, Boyuan Cheng, Haohao Cui, Chengcheng Li, Jingguo Li, Zhanrong Li · 2024 · Annals of Medicine
DNA methylation modification in Idiopathic pulmonary fibrosis
Lu Ren, Yanfen Chang, Shi-He Jiang, Xiao-Hong Li, Haipeng Cheng · 2024 · Frontiers in Cell and Developmental Biology
Epigenetic Control of Alveolar Macrophages: Impact on Lung Health and Disease
Nirmal Parajuli, Kalpana Subedi, Xzaviar Kaymar Solone, Aimin Jiang, Li Zhou, Qing‐Sheng Mi · 2025 · Cells
Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
Fengqin Zhang, Huihui Yue, Ruihan Dong, Jianhan He, Ling Zhou, Xinran Dou, lingling Wang, Pengdou Zheng, Zhenyu Mao, Xiaoyan Zhu et al. · 2024 · Respiratory Research
SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib
Francesca Ravanetti, Erica Ferrini, Luisa Ragionieri, Zahra Khalajzeyqami, Maria Nicastro, Yanto R. Ridwan, Alex KleinJan, Gino Villetti, Andrea Grandi, Franco Fabio Stellari · 2021 · Scientific Reports
Vincamine as an agonist of G protein-coupled receptor 40 effectively ameliorates pulmonary fibrosis in mice
Tong Zhao, Z Zhou, Shimei Zhao, Huiqi Wan, Honglin Li, Jiwei Hou, Jiaying Wang, Minyi Qian, Xu Shen · 2023 · Phytomedicine
Advancements in innate immune regulation strategies in islet transplantation
Kehang Duan, Jiao Liu, Jian Zhang, Tongjia Chu, Huan Liu, Fengxiang Lou, Ziyu Liu, Bing Zhao Gao, Shixiong Wei, Wei Feng · 2024 · Frontiers in Immunology
SARS-CoV-2 Spike Protein Induces Oxidative Stress and Senescence in Mouse and Human Lung
Joel S. Greenberger, WEN HOU, Donna S. Shields, Renee Fisher, Michael W. Epperly, Inderpal S. Sarkaria, Peter Wipf, Hong Wang · 2024 · In Vivo
GRaNIE and GRaNPA: Inference and evaluation of enhancer-mediated gene regulatory networks applied to study macrophages
Kamal, Aryan, Arnold, Christian, Claringbould, Annique, Moussa, Rim, Servaas, Nila H., Kholmatov, Maksim, Daga, Neha, Nogina, Daria, Mueller-Dott, Sophia, Reyes-Palomares, Armando et al. · 2021
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset
Jing Zhang, Yuan Zou, Longmin Chen, Fei Sun, Qianqian Xu, Qing Zhou, Yi Wang, Xi Luo, Na Wang, Yang Li et al. · 2023 · Nature Communications
Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway
Yaru Wang, Jinyu Zhang, Zhuo Yang, Changcheng Li, Chenming Zhang, Shengkai Sun, Ziyan Jiao, Guanghua Che, Hang Gao, Jinping Liu et al. · 2024 · Journal of Agricultural and Food Chemistry
Innovative treatment of age-related hearing loss using MSCs and EVs with Apelin
Shengqun Xu, Dongliang Liu, Fang Zhang, Yuan Tian · 2025 · Cell Biology and Toxicology
Sex hormones and epigenetic dysregulation in autoimmune disease
Minghuan Dai, Bao Mei, Feng Zheng, Esteban Ballestar · 2025 · Current Opinion in Immunology
MiR-6918-5p prevents renal tubular cell apoptosis by targeting MBD2 in ischemia/reperfusion-induced AKI
Jian Ming Pan, Guoxiu Zhang, Yingying Hu, Hongwei� Jiang, Xianming Tang, Dongshan Zhang · 2022 · Life Sciences
Macrophage expressed tartrate‐resistant acid phosphatase 5 promotes pulmonary fibrosis progression
Jesper Bergwik, Ravi K. V. Bhongir, Médea Padra, Anna Adler, Franziska Olm, Pernilla Lång, Sandra Lindstedt, Göran Andersson, Arne Egesten, Lloyd Tanner · 2024 · Immunology
Paroxetine protects against bleomycin-induced pulmonary fibrosis by blocking GRK2/Smad3 pathway
Kaochang Zhao, Hanxiang Nie, Zheng Tang, Guozhong Chen, Jizhen Huang · 2023 · Aging
The main bioactive compound of Panax notoginseng, notoginsenoside R1, alleviates pulmonary fibrosis via MBD2/SHIP and STAT3 pathway
Juan Wang, Yuwen Fang, Yongchun Zhou, Qin Chen, Jie Li, Yaxi Du, Xiuming Cui, Yuan Qu, Feng Ge · 2023 · Journal of Functional Foods
MiR-374a/b-5p Suppresses Cell Growth in Papillary Thyroid Carcinoma Through Blocking Exosomal ANXA1-Induced Macrophage M2 Polarization
Sanbao Liu · 2024 · Biochemical Genetics
Inhibition of peptidyl arginine deiminase-4 ameliorated pulmonary fibrosis via modulating M1/M2 polarisation of macrophages
Biswajit Panda, Shrilekha Chilvery, Priyanka Devi, Radha Kalmegh, Chandraiah Godugu · 2025 · Life Sciences
Tumor cell-derived osteopontin promotes tumor fibrosis indirectly via tumor-associated macrophages
Yuying Tan, Yong‐Guang Yang, Xiaoying Zhang, Lei Zhao, Xiaocong Wang, Wentao Liu · 2025 · Journal of Translational Medicine
MAP3K19 Promotes the Progression of Tuberculosis-Induced Pulmonary Fibrosis Through Activation of the TGF-β/Smad2 Signaling Pathway
Yu Xia, Haiyue Wang, Meihua Shao, Xuemei Liu, Feng Sun · 2023 · Molecular Biotechnology
Precision nanomedicine for pneumonocyte-targeting: Emerging strategies and clinical prospects in refractory pulmonary disease therapy
Sijie Wang, Huan‐Li Zhou, Jiapeng Mao, Yitao Zhang, Yuxin Qi, Pang Mei, Xizhi Jin, Junlei Zhang, Lihua Luo, Jian You · 2025 · Biomaterials
The impacts of allopolyploidization on Methyl-CpG-Binding Domain (MBD) gene family in Brassica napus
Yafang Xiao, Mengdi Li, Jianbo Wang · 2022 · BMC Plant Biology
Reprogramming Metabolism of Macrophages as a Target for Kidney Dysfunction Treatment in Autoimmune Diseases
Feng Tian, Hui Chen, Jianmin Zhang, Wei He · 2022 · International Journal of Molecular Sciences
Biomarkers in Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)
Alice R Cole, Christopher Paul Denton · 2022 · Current Treatment Options in Rheumatology
Environmental cadmium-induced circRNA-miRNA-mRNA network regulatory mechanism in human normal liver cell model
Zhi Qu, Lugang Deng, Chunqian Feng, Peisen Guo, Peixi Wang, Nan Liu · 2024 · Current Research in Toxicology
Diagnostic and predictive values of m5C‑associated genes in idiopathic pulmonary fibrosis
Lan Tian, Wanting Song, Jiabao Wu, Yi Lan, Limin Chen · 2024 · Molecular Medicine Reports
Targeted Inhibition of Aldose Reductase by Isoliquiritigenin Suppresses Fatty Acid Synthesis to Inhibit Macrophage M2 Polarization and Alleviate Pulmonary Fibrosis
Xiaofeng Mei, Qin Zhang, Wenbo Shao, Jiaping Zheng, Peng Zhao, Jiansheng Li · 2025 · Journal of Agricultural and Food Chemistry
Persistence of lung structural and functional alterations at one year post‐COVID‐19 is associated with increased serum PD‐L2 levels and altered CD4/CD8 ratio
Ivette Buendía-Roldán, Karen Martínez‐Espinosa, Maria‐Jose Aguirre, Hiram Aguilar‐Duran, Alexia Palma‐Lopez, Yadira Palacios, Andy Ruíz, Lucero A. Ramón‐Luing, Ranferi Ocaña‐Guzmán, Gloría Pérez-Rubio et al. · 2024 · Immunity Inflammation and Disease
Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension
Jixing Wu, Qian Huang, Qinghai Li, Yiya Gu, Yuan Zhan, Ting Wang, Jinkun Chen, Zhilin Zeng, Yongman Lv, Jianping Zhao et al. · 2022 · Frontiers in Oncology
IL-4-activated C/EBPβ is involved in alveolar macrophage polarization towards the M2 phenotype during pulmonary fibrosis induced by single-walled carbon nanotubes
Xiang Zhang, Jiaojiao Zhu, Shuxin Yang, Zhuomeng Yao, Sujuan Zhao, Yán Wāng, Chengfan Zhou, Qixing Zhu, Tong Shen · 2022 · Environmental Science Nano
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization
Huijun Qiu, Jiang Liu, Jingyi You, Zhou Ou, Chang Hao, Yi Shu, De-Yu Ma, Wenjing Zou, Linghuan Zhang, Enmei Liu et al. · 2024 · Genes & Diseases
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis
Guiyun Wang, Weixi Xie, Lang Deng, Xiaoting Huang, Mei Sun, Wei Qing Liu, Siyuan Tang · 2024 · Chinese Medicine
Discovery of novel capsaicin analogs as TRPV1 inhibitors for the treatment of idiopathic pulmonary fibrosis
Yu Cao, Yongju Wen, Zongyuan Zhou, Ruiying Xi, Shuai Wen, Jichao Zhang, Apichart Suksamrarn, Guolin Zhang, Xiaoxia Lü, Fei Wang · 2024 · European Journal of Medicinal Chemistry
Arrhythmogenic Hearts in PKD2 Mutant Mice Are Characterized by Cardiac Fibrosis, Systolic, and Diastolic Dysfunctions
Farideh Amirrad, Rajasekharreddy Pala, Kiumars Shamloo, Brian S. Muntean, Surya M. Nauli · 2021 · Frontiers in Cardiovascular Medicine
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation
Jianhan He, Huihui Yue, Shufei Zhang, Ruihan Dong, Fengqin Zhang, Xuewen Wang, Ke Wang, Huilan Zhang, Danlei Yang, Zhaoxing Dong et al. · 2025 · Respiratory Research
MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis
Yukai Jing, Yunfei Zhang, Xiaocui Wang, Yufen Wang, Ying Hu, Bin Wen, Xin Dai, Xuemei Duan, Haonan Li, Shumin Dong et al. · 2025 · Cell Death and Disease
The role of MBD2 in immune cell development, function, and autoimmune diseases
Yunfei Zhang, Yufeng Fan, Ying Hu, Xiaocui Wang, Bin Wen, Xuemei Duan, Haonan Li, Shumin Dong, Ze Yan, Weiwei Zhang et al. · 2025 · Cell Death Discovery
Cellular and Molecular Diversity in Scleroderma
Monique Hinchcliff, Rolando García-Milian, Stefano Di Donato, Karin Evelyn Dill, Elizabeth Bundschuh, Francesco Del Galdo · 2021 · Seminars in Immunology
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways
San Fu, Xianrui Song, Yingying Hu, Qingwei ZHU, Xin-miao Lv, Xiaoyan TANG, Mian Zhang · 2023 · Chinese Journal of Natural Medicines
Prevention of Intrauterine Adhesion with Platelet‐Rich Plasma Double‐Network Hydrogel
Zhuomin Wang, Ying Gu, Yiyuan Qu, Xujia Huang, Tao Sun, Wei Wu, Qianyu Hu, Chen Xiao, Li J. Yu, Huafei Zhao et al. · 2024 · Advanced Biology
Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis
Yuyu Jiang, Yunkai Zhang, Xiaohui Wang, Yan Xiang, Zeting Wang, Bo Wang, Yingying Ding, Ying Gao, Bing Rui, Jie Bai et al. · 2025 · Cell Reports
Heparanase inhibition mitigates bleomycin-induced pulmonary fibrosis in mice by reducing M2 macrophage polarization
Long He, Qianying Lv, Jing Luo, Yide Guo, He Sun, Ming Zong, Lieying Fan · 2025 · Immunology Letters
Inhalable Mucus-Penetrating Engineered Hybrid Nanomedicine for Enhanced Treatment of Idiopathic Pulmonary Fibrosis
Jinglin Zou, Cong Jiang, Jing Zhang, Shiyue Wan, Yuzi Yang, Yuheng Leng, Shuqi Wang, Xinlin Jia, Yuanqing Mao, Dapeng Zhang et al. · 2025 · Nano Letters
RETRACTED: Baicalein exerts beneficial effects in lipopolysaccharide-induced pulmonary inflammation by modulating macrophage polarization and inhibiting pyroptosis
Yile Kou, Lu Zhang, Zhaoling Shi, Guocheng Zhang, Jing Chang, Qian Bai, Na Gao, Hui Ding · 2024 · Human & Experimental Toxicology · Retracted
Blocking ATF4 attenuates pulmonary fibrosis by preventing lung fibroblast activation and macrophage M2 program
Menglin Zou, Weishuai Zheng, Xingxing Hu, Han Gao, Qinhui Hou, Weiwei Song, Yuan Liu, Zhenshun Cheng · 2025 · International Journal of Biological Macromolecules
Versatile functions of methyl-CpG-binding domain 2 (MBD2) in cellular characteristics and differentiation
Rabia Tuana Lekesiz, Kasım Kağan Koca, Gizem Kugu, Zihni Onur Çalışkaner · 2025 · Molecular Biology Reports
Integrating metabolomics and network pharmacology analysis provides new insights into the lipid metabolism disorder of Abrus mollis
Mingjuan Huang, Xue Wang, Yixiang Lu, Qiaowen Zhou, Jiemei Liang, Quanxin Li, Liangbo Li, Lanlan Fan · 2025 · Journal of Ethnopharmacology
MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis
Nirmal Parajuli, Yi Yao, Namir Khalasawi, Congcong Yin, Qiong Zhang, Indra Adrianto, Aakash Hans, Li Zhou, Qing‐Sheng Mi · 2025 · Frontiers in Immunology
Nicotinamide phosphoribose transferase facilitates macrophage-mediated pulmonary fibrosis through the Sirt1-Smad7 pathway in mice
Tianwei Zhan, Ya-Ling Chen, Lingjun Dong, Tao-Feng Wei, Dongning Lu, Qi Wang, Zixiang Wu, Jiajie Xu, Minghua Ge · 2024 · European Journal of Pharmacology
Administration of Liposomal-Based Pde3b Gene Therapy Protects Mice Against Collagen-Induced Rheumatoid Arthritis via Modulating Macrophage Polarization
Longmin Chen, Qing Zhou, Xun Fang, Qianqian Xu, Yuan Zou, Jing Zhang · 2024 · International Journal of Nanomedicine
From inflammatory activation to fibrotic remodeling: the central role of macrophage heterogeneity in frozen shoulder
Liang Hao, Jianmin Liu · 2026 · Frontiers in Immunology
The gene regulatory networks shaping macrophage plasticity and altered function in fibrosis
Zsuzsanna Kolostyák, László Nagy · 2026 · Frontiers in Immunology
m6A RNA methylation: The latent string-puller in fibrosis
Xinglan He, Bingsi Tang, Puyu Zou, Zehong Song, Jiani Liu, Zixin Pi, Yangfan Xiao, Rong Xiao · 2024 · Life Sciences
IFIT3 mediates TBK1 phosphorylation to promote activation of pDCs and exacerbate systemic sclerosis in mice
Xiangyang Huang, Yi Liu, Xia Rong, Yiheng Zhao, Dan Feng, Jun Wang, Wanhong Xing · 2024 · Clinical and Translational Medicine
Targeting Caveolin-1 for enhanced rotator cuff repair: findings from single-cell RNA sequencing
Shanhong Fang, Songye Wu, Peng Chen · 2025 · Cell Death Discovery
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2
Yang Zhou, Guifang Yang, Jiqiang Liu, Shuo Yao, Jingsi Jia, Xianming Tang, Xun Gong, Fang Wan, Ren‐Chin Wu, Zhenyu Zhao et al. · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
New insights into methylome alterations and consequences during myofibroblastic differentiation in pulmonary fibrosis
Arnaud Mailleux, Bruno Crestani · 2022 · European Respiratory Journal
Role of FGF19 in regulating mitochondrial dynamics and macrophage polarization through FGFR4/AMPKα-p38/MAPK Axis in bleomycin-induced pulmonary fibrosis
Yang Li, Hong Zhang, Bing Li, Xin Yi, Xinri Zhang · 2025 · Cytokine
SESN3 restrains the progress of idiopathic pulmonary fibrosis by targeting the activity of FOSL2
Yun Sun, Dan Chen, Fengjie Liu, Ting Liu · 2025 · Biology Direct
Plasma apolipoprotein E protein attenuates pulmonary fibrosis through LRP1 and PLAU dual receptor-mediated TGF-β/Smad inhibition
Haiyang Zhang, Yu Xie, Gang Wei, Juan Liu, Wenru Shang, Manyi Pan, Yuxin Zou, Lifeng Yan, Tianyu Zhou, Jiachang Chi et al. · 2025 · Journal of Advanced Research
Transcriptomic and metabolomic insights into gabapentin’s therapeutic role in neurogenic inflammation of rosacea
Ziqi Jiang, Tian Ding, Yan Zhao, Mao Luo, Yishu Tang, Yuxuan Zhang, Bin Wei · 2026 · Communications Biology
Dual-Functional PDA@Au/CeO 2 Nanozymes Enable CT Tracking and Potent Antifibrotic MSC Therapy
Shuhong Guan, Yiwen Yao, Yu Ding, Long Zhang, Junkang Huangfu, Xiyao Chen, Xiaoyu Wang, Jun Zhou · 2026 · ACS Applied Materials & Interfaces
Methyl CpG binding domain protein 2 (MBD2) in inflammation
Qian Lei, Wei Zhang · 2022 · Chinese Medical Journal
Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-β1 signaling
Farideh Amirrad, Gregory A. Fishbein, Robert A. Edwards, Surya M. Nauli · 2022 · Cell and Tissue Research
Exosome-mediated effects of BRCA1 on cardiovascular artery disease
Hairui Yu, Wei Dong, Weiqian Liao, Xiaoming Shang, Dandan Li, Chan Liu, Qimei Deng, Huangfu Haiquan · 2025 · Cell Biology and Toxicology
Possible Therapeutic Targets from Derivatives of Natural Marine Products Based on PI3K/AKT Dependent Inhibitors in Viral Infection COVID-19
Elahe Aleebrahim‐Dehkordi · 2022 · Cellular Physiology and Biochemistry
Transcriptome analysis of chicken fibroblast following transforming growth factor β1-mediated activation
Taijiang Hou, Lin Zhang, Liang Zhao, Feng Gao, Tong Xing · 2025 · Poultry Science
MBD2 deficiency attenuates CCl4-induced hepatic fibrosis by inhibiting M2 macrophage polarization
Yu Wen, Ruihua Li, Yixian Wang, Yanan Wang, Yaxuan Huang, Yanxiang Zhang, Hao Nie, Lian Liu, Hui Chen, Bing Zheng et al. · 2025 · International Immunopharmacology
Echinacoside ameliorates bleomycin-induced idiopathic pulmonary fibrosis by regulating macrophage polarization
Yifan Zhang, Liming Fan, Mengni Wang · 2025 · Journal of Molecular Histology
Exploration of lactylation genes in bronchopulmonary dysplasia: Implications for immune regulation and disease mechanisms
Yue Gao, Yang Yang, Lu Xia, Song Wang, Wei Sun, Xin Feng, Yurong Sun · 2025 · Journal of the Formosan Medical Association
The role of free‐fatty acid receptors FFA1 and FFA4 in organ fibrosis
Priyanka F. Karmokar, Nader H. Moniri · 2026 · British Journal of Pharmacology
Synergistic regulation of TGF-β1/Smad2/3 signaling and inflammatory pathways via SA/NAC-based nanoplatforms: a novel strategy to enhance anti-fibrotic therapeutic outcomes in idiopathic pulmonary fibrosis
Ce Li, Yichao Yuan, Yaqing Bao, Yuan Ni, Nan Chen, Jigang Piao, Lu Wang, Zhihong Zhu · 2026 · Journal of Nanobiotechnology
Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure
Xiaoqin Liu, Xuhua Jiang, Xueyun Zhang, Qiankun Hu, Xueping Yu, Jian Sun, Mingqin Lu, Zhang Jiming, Yuxian Huang · 2026 · Frontiers in Immunology
Identification of key macrophage-related genes in systemic sclerosis–associated interstitial lung disease based on single-cell and bulk transcriptomic data
Ting Zhao, Yulin Wang, Fu-An Lin · 2026 · PLoS ONE
The interplay of ferroptosis and oxidative stress in pulmonary fibrosis: from mechanisms to treatment
Peishuo Yan, Jia‐Yi Wang, Zhen Lei, Hongbo Chang, Weili Shi, Shangzeng Wang · 2026 · Frontiers in Cell and Developmental Biology
Respiratory viruses as key drivers of pulmonary fibrosis: integrated pathways from barrier injury to immune–fibrotic crosstalk
Chang Liu, Xindi Yuan · 2026 · Virology
One-Step Genotyping Method in loxP-Based Conditional Knockout Mice Generated by CRISPR-Cas9 Technology
He Zhu, Siqian Liu, Wenxi He, Fei Sun, Yang Li, Ping Chang Yang, Qilin Yu, Shu Zhang · 2022 · Molecular Biotechnology
Role of macrophages in the pathogenesis of pulmonary fibrosis
Anastasia A. Maksimova, Е. Ya. Shevela, Elena Removna Chernykh · 2024 · Immunologiya
Modulating ATOH1 and POU4F3 Pathways to Enhance Hair Cell Regeneration and Inhibit Ferroptosis in Cochlear Support Cells
Rong Yu, Kai Wang, Yu Lu, Wenyu Xiong, Qing Luo, Wugen Luo, Hongqun Jiang, Hua Yang · 2025 · The FASEB Journal
Macrophage-Targeted Nanomedicines
Eder Lilia Romero, María Julia Altube, Ana Paula Perez, María José Morilla · 2023 · Interdisciplinary biotechnological advances
Polydatin-curcumin formulation alleviates CTD-ILD-like lung injury in mice via GABBR/PI3K/AKT/TGF-β pathway
Zhengju Zhang, Yao Zhang, Qing‐Yi Lu, Yanan Wang, Guodong Li, Guoju Jin, Wei‐Guo Ma, Yi Liu, Yang Lei, Hui Liu et al. · 2025 · Frontiers in Pharmacology
Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Y. M. Wong, Ricardo Couto, Byron D. Yépez V., Bernhard Seifried, Paul Moquin et al. · 2025 · Advanced Healthcare Materials
Monocyte-mediated mechanisms in idiopathic pulmonary fibrosis: opportunities for early intervention
Zhiguo MAO, Ying Liu, Chengfu Han, Xingyi Yang, Xiangke Lin, Shuo Tian, Mingsan Miao · 2026 · APOPTOSIS
Dual-drug nanoplatform HPA@NPs reprograms the fibrotic microenvironment by suppressing EMT and M2 macrophage polarization in pulmonary fibrosis
An Soo Chang, Yi Wang, Zan Cui, Yuan-Yuan Liu, Ling-Qi Meng, Jia-Shi, Zhi-Yong Qin, Jianing Gong · 2026 · International Immunopharmacology
Oxidized mtDNA Contributes to Pulmonary Inflammation and Fibrosis in Bleomycin‐Induced Lung Injury
Ye Mao, Xinyu Tian, Jiayuan Ai, Xiaoting Zhou, Yanghong Ni, Dandan Wan, Min Luo, Xiawei Wei · 2026 · MedComm
Metal-based nanoparticles for reprogramming macrophage polarization: Advances in immunomodulatory nanotherapeutics
Xing Du, Kai Ding, Zehao Mao, Jiangyu Li, Yongmei Zhao, Tianqing Liu · 2026 · International Journal of Pharmaceutics X
Quercetin loaded ZIF-8 coated human serum albumin nanoparticles relieve pulmonary fibrosis via NUAK1-YAP axis
Chen Ke-gong, Chun-Sheng Zhang, Yu-Hang Ma, Han-Qing Xu, Chao-Long Jin, Lin Ji, Guang-Yao Ning, Xiao-Hui Guo, Ren-Quan Zhang, Pei-An Cai et al. · 2026 · Biomaterials Advances
Targeting FGG alleviates cholestatic fibrosis by inhibiting hepatic stellate cell activation and regulating macrophage homeostasis
Wei, Qianyi, Li, Minghao, Yang, Qiwei, Ren, Mengyao, Liu, Xudong, Cai, Xin, Shi, Jihua, Huang, Changjun, Wang, Yun, Zhang, Yi et al. · 2026 · Journal of Nanobiotechnology
Functionele biodiversiteit : micro-organismen
J. Bloem · 2009 · Socio-Environmental Systems Modeling
Fibrose pulmonar pós-COVID-19: uma revisão narrativa
Fernanda Caroline Correa Freitas, Ana Luiza Scussulim Florindo Alcure Dias, Antônio Marcos dos Reis Júnior, Daniele Milagres Batista, Jyennyffer Barral Rodrigues, João Gabriel Leite, Juliana Cesconetto, Julia Hamacek Lopes da Costa, Luiza Giordani Mileo, Henrique de Castro Mendes · 2022 · Revista Eletrônica Acervo Saúde
Local Delivery of Bcar3 siRNA by Nano-Self-Assembly for Treating Pulmonary Fibrosis via Blocking the Interaction of Macrophages and Fibroblasts
Chenxi Zeng, Qi Wang, Xuhan liu, Congjian Wang, Qing Zhou, Xiangning Fu, Jun Yu, Weining Xiong, Yi Wang, Xuetao Ju · 2023 · Research Square
The effect of fluoroquinolones on the cancer development in patients with interstitial lung disease and virus infection
Jun‐Jun Yeh, Yi-Fan Sun, Tang Hsien-Chin, Chia-Hsun Li, Hsuan-Min Kao, Cheng‐Li Lin, Chia‐Hung Kao · 2024 · Research Square
On the pathogenesis of COVID-19: the role of transforming growth factor beta
Andrey Valerievich Budnevsky, Е. S. Ovsyannikov, В. В. Шишкина, N. G. Alekseeva, Первеева Инна Михайловна, Avag G. Kitoyan, Любовь Николаевна Антакова · 2024 · Bulletin of Siberian Medicine