Cited by 38

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Ameliorating the hallmarks of cellular senescence in skeletal muscle myogenic progenitors in vitro and in vivo

Shahini, Aref, Rajabian, Nika, Choudhury, Debanik, Shahini, Shahryar, Vydiam, Kalyan, Nguyen, Thy, Kulczyk, Joseph, Santarelli, Tyler, Ikhapoh, Izuagie, Zhang, Yali, Wang, Jianmin, Liu, Song, Stablewski, Aimee, Thiyagarajan, Ramkumar, Seldeen, Kenneth, Troen, Bruce R., Peirick, Jennifer, Lei, Pedro, Andreadis, Stelios T.·2021·Science Advances

Abstract

The embryonic factor NANOG reverses aging hallmarks and rejuvenates senescent skeletal muscle progenitors.

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Crossref · 10.1126/sciadv.abe5671

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  • NANOG alone has a pivotal role in ameliorating senescence hallmarks and inducing rejuvenation in myogenic progenitor cells both in vitro and in vivo.

    “Shahini et al. showed that NANOG alone has a pivotal role in ameliorating of senescence hallmarks and inducing rejuvenation in myogenic progenitor cells both in vitro and in vivo 61 .”
  • Other transcription factors might represent a safer alternative to induce epigenetic rejuvenation.

    “further supporting the idea that other transcription factors might represent a safer alternative to induce epigenetic rejuvenation as also reported by other groups 61,118 .”

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Research works printed but not linked: 67

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Metadata

Authors
Shahini, A., Rajabian, N., Choudhury, D., Shahini, S., Vydiam, K., Nguyen, T., Kulczyk, J., Santarelli, T., Ikhapoh, I., Zhang, Y., Wang, J., Liu, S., Stablewski, A., Thiyagarajan, R., Seldeen, K., Troen, B. R., Peirick, J., Lei, P., & Andreadis, S. T.
Venue
Science Advances
Published
2021-09-03
Volume
7
Issue
36
ISSN
2375-2548
Cited by
38
References
11
Language
en

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