The DOI matches its Crossref record.
Direct Interaction of Arabidopsis Cryptochromes with COP1 in Light Control Development
Abstract
Arabidopsis seedling photomorphogenesis involves two antagonistically acting components, COP1 and HY5. COP1 specifically targets HY5 for degradation via the 26 S proteasome in the dark through their direct physical interaction. Little is known regarding how light signals perceived by photoreceptors are transduced to regulate COP1. Arabidopsis has two related cryptochromes (cry1 and cry2) mediating various blue/ultraviolet-A light responses. Here we show that both photoactivated cryptochromes repress COP1 activity through a direct protein-protein contact and that this direct regulation is primarily responsible for the cryptochrome-mediated blue light regulation of seedling photomorphogenic development and genome expression profile.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
The genetic basis of flowering responses to seasonal cues
Andrés, F., & Coupland, G. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3291 · Cited by 1,538
Light-Regulated Plant Growth and Development
Kami, C., Lorrain, S., Hornitschek, P., & Fankhauser, C. (2010) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)91002-8 · Cited by 927
The cryptochromes: blue light photoreceptors in plants and animals
Chaves, I., Pokorny, R., Byrdin, M., Hoang, N., Ritz, T., Brettel, K., Essen, L.-O., van der Horst, G. T. J., Batschauer, A., & Ahmad, M. (2011) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042110-103759 · Cited by 845
Ma, L., Li, J., Qu, L., Hager, J., Chen, Z., Zhao, H., & Deng, X. W. (2001) · The Plant Cell · doi:10.1105/tpc.010229 · Cited by 561
Self-citationPhytochrome Signaling Mechanisms
Li, J., Li, G., Wang, H., & Wang Deng, X. (2011) · The Arabidopsis Book · doi:10.1199/tab.0148 · Cited by 561
Self-citation
Metadata
- Authors
- Wang, H., Ma, L.-G., Li, J.-M., Zhao, H.-Y., & Deng, X. W.
- Venue
- Science
- Published
- 2001-10-05
- Volume
- 294
- Issue
- 5540
- Pages
- 154-158
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2006153112
- Cited by
- 524
- References
- 0
- FWCI
- 30.90
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Direct Interaction of Arabidopsis Cryptochromes with COP1 in Light Control Development. https://app.cochat.ai/papers/10.1126/science.1063630
- The paper
- Wang, H., Ma, L.-G., Li, J.-M., Zhao, H.-Y., & Deng, X. W. (2001). Direct Interaction of Arabidopsis Cryptochromes with COP1 in Light Control Development. Science. https://doi.org/10.1126/science.1063630
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
