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Cited by 665

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Regulation of Brassinosteroid Signaling by a GSK3/SHAGGY-Like Kinase

Li, Jianming, Nam, Kyoung Hee·2002·Science

Abstract

GSK3/SHAGGY is a highly conserved serine/threonine kinase implicated in many signaling pathways in eukaryotes. Although many GSK3/SHAGGY-like kinases have been identified in plants, little is known about their functions in plant growth and development. Here we show that the Arabidopsis BRASSINOSTEROID-INSENSITIVE 2 ( BIN2 ) gene encodes a GSK3/SHAGGY-like kinase. Gain-of-function mutations within its coding sequence or its overexpression inhibit brassinosteroid (BR) signaling, resulting in plants that resemble BR-deficient and BR-response mutants. In contrast, reduced BIN2 expression via cosuppression partially rescues a weak BR-signaling mutation. Thus, BIN2 acts as a negative regulator to control steroid signaling in plants.

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Metadata

Authors
Li, J., & Nam, K. H.
Venue
Science
Published
2002-02-15
Volume
295
Issue
5558
Pages
1299-1301
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1620028706
Cited by
665
References
1
FWCI
36.80
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Regulation of Brassinosteroid Signaling by a GSK3/SHAGGY-Like Kinase. https://app.cochat.ai/papers/10.1126/science.1065769
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Li, J., & Nam, K. H. (2002). Regulation of Brassinosteroid Signaling by a GSK3/SHAGGY-Like Kinase. Science. https://doi.org/10.1126/science.1065769

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