The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Regulation of Brassinosteroid Signaling by a GSK3/SHAGGY-Like Kinase
Abstract
GSK3/SHAGGY is a highly conserved serine/threonine kinase implicated in many signaling pathways in eukaryotes. Although many GSK3/SHAGGY-like kinases have been identified in plants, little is known about their functions in plant growth and development. Here we show that the Arabidopsis BRASSINOSTEROID-INSENSITIVE 2 ( BIN2 ) gene encodes a GSK3/SHAGGY-like kinase. Gain-of-function mutations within its coding sequence or its overexpression inhibit brassinosteroid (BR) signaling, resulting in plants that resemble BR-deficient and BR-response mutants. In contrast, reduced BIN2 expression via cosuppression partially rescues a weak BR-signaling mutation. Thus, BIN2 acts as a negative regulator to control steroid signaling in plants.
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Cites
BRASSINOSTEROIDS: Essential Regulators of Plant Growth and Development
Clouse, S. D., & Sasse, J. M. (1998) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.49.1.427 · Cited by 1,462
Cited by
BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
Nam, K. H., & Li, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00814-0 · Cited by 1,217
Self-citationKim, T.-W., Guan, S., Sun, Y., Deng, Z., Tang, W., Shang, J.-X., Sun, Y., Burlingame, A. L., & Wang, Z.-Y. (2009) · Nature Cell Biology · doi:10.1038/ncb1970 · Cited by 693
Tanabe, S., Ashikari, M., Fujioka, S., Takatsuto, S., Yoshida, S., Yano, M., Yoshimura, A., Kitano, H., Matsuoka, M., Fujisawa, Y., et al. (2005) · The Plant Cell · doi:10.1105/tpc.104.024950 · Cited by 555
Comprehensive Comparison of Auxin-Regulated and Brassinosteroid-Regulated Genes in Arabidopsis
Goda, H., Sawa, S., Asami, T., Fujioka, S., Shimada, Y., & Yoshida, S. (2004) · Plant Physiology · doi:10.1104/pp.103.034736 · Cited by 499
Brassinosteroid Signaling Network and Regulation of Photomorphogenesis
Wang, Z.-Y., Bai, M.-Y., Oh, E., & Zhu, J.-Y. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163450 · Cited by 490
Metadata
- Authors
- Li, J., & Nam, K. H.
- Venue
- Science
- Published
- 2002-02-15
- Volume
- 295
- Issue
- 5558
- Pages
- 1299-1301
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1620028706
- Cited by
- 665
- References
- 1
- FWCI
- 36.80
- Type
- journal article
- Language
- en
- Open access
- closed
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