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Photothermal Imaging of Nanometer-Sized Metal Particles Among Scatterers

Boyer, David, Tamarat, Philippe, Maali, Abdelhamid, Lounis, Brahim, Orrit, Michel·2002·Science

Abstract

Ambient optical detection of labeled molecules is limited for fluorescent dyes by photobleaching and for semiconducting nanoparticles by “blinking” effects. Because nanometer-sized metal particles do not optically bleach, they may be useful optical labels if suitable detection signals can be found. We demonstrate far-field optical detection of gold colloids down to diameters of 2.5 nanometers with a photothermal method that combines high-frequency modulation and polarization interference contrast. The photothermal image is immune to the effects of scattering background, which limits particle imaging through Rayleigh scattering to diameters larger than 40 nanometers.

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Metadata

Authors
Boyer, D., Tamarat, P., Maali, A., Lounis, B., & Orrit, M.
Venue
Science
Published
2002-08-16
Volume
297
Issue
5584
Pages
1160-1163
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2122932285
Cited by
978
References
0
FWCI
9.57
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Photothermal Imaging of Nanometer-Sized Metal Particles Among Scatterers. https://app.cochat.ai/papers/10.1126/science.1073765
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Boyer, D., Tamarat, P., Maali, A., Lounis, B., & Orrit, M. (2002). Photothermal Imaging of Nanometer-Sized Metal Particles Among Scatterers. Science. https://doi.org/10.1126/science.1073765

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.