The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Ectoderm to Mesoderm Lineage Switching During Axolotl Tail Regeneration
Abstract
Foreign environments may induce adult stem cells to switch lineages and populate multiple tissue types, but whether this mechanism is used for tissue repair remains uncertain. Urodele amphibians can regenerate fully functional, multitissue structures including the limb and tail. To determine whether lineage switching is an integral feature of this regeneration, we followed individual spinal cord cells live during tail regeneration in the axolotl. Spinal cord cells frequently migrate into surrounding tissue to form regenerating muscle and cartilage. Thus, in axolotls, cells switch lineage during a real example of regeneration.
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Citations
Cites
Changing potency by spontaneous fusion
Ying, Q.-L., Nichols, J., Evans, E. P., & Smith, A. G. (2002) · Nature · doi:10.1038/nature729 · Cited by 1,494
Cited by
De Santa, F., Totaro, M. G., Prosperini, E., Notarbartolo, S., Testa, G., & Natoli, G. (2007) · Cell · doi:10.1016/j.cell.2007.08.019 · Cited by 965
Cells keep a memory of their tissue origin during axolotl limb regeneration
Kragl, M., Knapp, D., Nacu, E., Khattak, S., Maden, M., Epperlein, H. H., & Tanaka, E. M. (2009) · Nature · doi:10.1038/nature08152 · Cited by 850
Self-citationLepilina, A., Coon, A. N., Kikuchi, K., Holdway, J. E., Roberts, R. W., Burns, C. G., & Poss, K. D. (2006) · Cell · doi:10.1016/j.cell.2006.08.052 · Cited by 833
The glial identity of neural stem cells
Doetsch, F. (2003) · Nature Neuroscience · doi:10.1038/nn1144 · Cited by 724
Distinct Wnt signaling pathways have opposing roles in appendage regeneration
Stoick-Cooper, C. L., Weidinger, G., Riehle, K. J., Hubbert, C., Major, M. B., Fausto, N., & Moon, R. T. (2007) · Development · doi:10.1242/dev.001123 · Cited by 532
Metadata
- Authors
- Echeverri, K., & Tanaka, E. M.
- Venue
- Science
- Published
- 2002-12-06
- Volume
- 298
- Issue
- 5600
- Pages
- 1993-1996
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1980679514
- Cited by
- 232
- References
- 1
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Echeverri, K., & Tanaka, E. M. (2002). Ectoderm to Mesoderm Lineage Switching During Axolotl Tail Regeneration. Science. https://doi.org/10.1126/science.1077804
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
