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Cited by 1,113

The DOI matches its Crossref record.

Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles

Savić, Radoslav, Luo, Laibin, Eisenberg, Adi, Maysinger, Dusica·2003·Science
DOI 10.1126/science.1078192
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Abstract

Block copolymer micelles are water-soluble biocompatible nanocontainers with great potential for delivering hydrophobic drugs. An understanding of their cellular distribution is essential to achieving selective delivery of drugs at the subcellular level. Triple-labeling confocal microscopy in live cells revealed the localization of micelles in several cytoplasmic organelles, including mitochondria, but not in the nucleus. Moreover, micelles change the cellular distribution of and increase the amount of the agent delivered to the cells. These micelles may thus be worth exploring for their potential to selectively deliver drugs to specified subcellular targets.

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Metadata

Authors
Savić, R., Luo, L., Eisenberg, A., & Maysinger, D.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2003-04-25
Volume
300
Issue
5619
Pages
615-618
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.1078192
OpenAlex
W1662084969
Cited by
1,113
References
0
FWCI
33.17
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles. https://app.cochat.ai/papers/10.1126/science.1078192
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Savić, R., Luo, L., Eisenberg, A., & Maysinger, D. (2003). Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles. Science. https://doi.org/10.1126/science.1078192

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.