Nanomedicine: current status and future prospects

In vivo cancer targeting and imaging with semiconductor quantum dots

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Drug Delivery Systems: Entering the Mainstream

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Molecular Beacons: Probes that Fluoresce upon Hybridization

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Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

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Probing the Cytotoxicity of Semiconductor Quantum Dots

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Biodegradable nanoparticles for drug and gene delivery to cells and tissue

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Designing materials for biology and medicine

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In Vivo Imaging of Quantum Dots Encapsulated in Phospholipid Micelles

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Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots

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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo

Larson, D. R., Zipfel, W. R., Williams, R. M., Clark, S. W., Bruchez, M. P., Wise, F. W., & Webb, W. W. (2003) · Science · doi:10.1126/science.1083780 · Cited by 2,290 · see citing works

Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers

Silva, G. A., Czeisler, C. M., Niece, K. L., Beniash, E., Harrington, D. A., Kessler, J. A., & Stupp, S. I. (2004) · Science · doi:10.1126/science.1093783 · Cited by 2,169 · see citing works

The potential environmental impact of engineered nanomaterials

Colvin, V. L. (2003) · Nature Biotechnology · doi:10.1038/nbt875 · Cited by 2,161 · see citing works

Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping

Kim, S., Lim, Y. T., Soltesz, E. G., Grand, A. M. D., Lee, J., Nakayama, A., Parker, J. A., Mihaljevic, T., Laurence, R. G., Dor, D. M., et al. (2003) · Nature Biotechnology · doi:10.1038/nbt920 · Cited by 2,087 · see citing works

Luminescent quantum dots for multiplexed biological detection and imaging

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Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

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Long-term multiple color imaging of live cells using quantum dot bioconjugates

Jaiswal, J. K., Mattoussi, H. M., Mauro, J. M., & Simon, S. M. (2002) · Nature Biotechnology · doi:10.1038/nbt767 · Cited by 2,002 · see citing works

Noninvasive detection of clinically occult lymph-node metastases in prostate cancer

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Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

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Genes Expressed in Human Tumor Endothelium

Croix, B. S., Rago, C., Velculescu, V. E., Traverso, G., Romans, K. E., Montgomery, E. A., Lal, A., Riggins, G. J., Christoph Lengauer, C., Vogelstein, B., et al. (2000) · Science · doi:10.1126/science.289.5482.1197 · Cited by 1,845 · see citing works

Ligand-targeted therapeutics in anticancer therapy

Allen, T. M. (2002) · Nature reviews. Cancer · doi:10.1038/nrc903 · Cited by 1,648 · see citing works

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis

Wadia, J. S., Stan, R. V., & Dowdy, S. F. (2004) · Nature Medicine · doi:10.1038/nm996 · Cited by 1,647 · see citing works

Pharmacokinetics of Pegylated Liposomal Doxorubicin

Gabizón, A., Shmeeda, H., & Barenholz, Y. (2003) · Clinical Pharmacokinetics · doi:10.2165/00003088-200342050-00002 · Cited by 1,639 · see citing works

Nanosuspensions in drug delivery

Rabinow, B. E. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1494 · Cited by 1,528 · see citing works

Targeted drug delivery via the folate receptor

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Diffusion Dynamics of Glycine Receptors Revealed by Single-Quantum Dot Tracking

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Cell-penetrating Peptides

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Nanocrystal targeting in vivo

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Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance

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Optimizing Liposomes for Delivery of Chemotherapeutic Agents to Solid Tumors

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Exposure to Carbon Nanotube Material: Assessment of Nanotube Cytotoxicity using Human Keratinocyte Cells

Shvedova, A. A., Castranova, V., Kisin, E. R., Schwegler‐Berry, D., Murray, A. R., Gandelsman, V., Maynard, A., & Baron, P. A. (2003) · Journal of Toxicology and Environmental Health · doi:10.1080/713853956 · Cited by 1,245 · see citing works

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

Moghimi, S. M., & Szebeni, J. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00033-x · Cited by 1,228 · see citing works

Nanotech approaches to drug delivery and imaging

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Noninvasive Imaging of Quantum Dots in Mice

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Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles

Savić, R., Luo, L., Eisenberg, A., & Maysinger, D. (2003) · Science · doi:10.1126/science.1078192 · Cited by 1,113 · see citing works

Amphiphilic block copolymers for drug delivery

Adams, M. L., Lavasanifar, A., & Kwon, G. S. (2003) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10397 · Cited by 1,078 · see citing works

Rapid endo‐lysosomal escape of poly(DL‐lactide‐ co glycolide) nanoparticles: implications for drug and gene delivery

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Introduction to Nanotechnology

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Dendritic cell immunotherapy: mapping the way

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Tumor Regression by Targeted Gene Delivery to the Neovasculature

Hood, J. D., Bednarski, M. D., Frausto, R. F., Guccione, S., Reisfeld, R. A., Xiang, R., & Cheresh, D. A. (2002) · Science · doi:10.1126/science.1070200 · Cited by 858 · see citing works

Cancer cells compress intratumour vessels

Padera, T. P., Stoll, B. R., Tooredman, J. B., Capen, D., Tomaso, E. D., & Jain, R. K. (2004) · Nature · doi:10.1038/427695a · Cited by 857 · see citing works

Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging

Kooi, M. E., Cappendijk, V. C., Cleutjens, K. B. J. M., Kessels, A. G. H., Kitslaar, P. J. E. H. M., Borgers, M., Frederik, P. M., Daemen, M. J. A. P., & van Engelshoven, J. M. A. (2003) · Circulation · doi:10.1161/01.cir.0000068315.98705.cc · Cited by 798 · see citing works

Endothelial cell diversity revealed by global expression profiling

Chi, J., Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1434429100 · Cited by 773 · see citing works

Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells

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Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs

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Multifunctional nanorods for gene delivery

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Gene therapy: trials and tribulations

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Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy

Voura, E. B., Jaiswal, J. K., Mattoussi, H. M., & Simon, S. M. (2004) · Nature Medicine · doi:10.1038/nm1096 · Cited by 688 · see citing works

Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor

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Liposome application: problems and prospects.

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The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development

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Regulation of Angiogenesis in Vivo by Ligation of Integrin α5β1 with the Central Cell-Binding Domain of Fibronectin

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Steps toward mapping the human vasculature by phage display

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Role of tumor–host interactions in interstitial diffusion of macromolecules: Cranial vs. subcutaneous tumors

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Magnetic Resonance Imaging of Atherosclerotic Plaque With Ultrasmall Superparamagnetic Particles of Iron Oxide in Hyperlipidemic Rabbits

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Supramolecular Drug‐Delivery Systems Based on Polymeric Core–Shell Architectures

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Immunomicelles: Targeted pharmaceutical carriers for poorly soluble drugs

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Semi‐Automated Synthesis and Screening of a Large Library of Degradable Cationic Polymers for Gene Delivery

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Advances in vaccine adjuvants

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A tumor-homing peptide with a targeting specificity related to lymphatic vessels

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Endocytosis and targeting of exogenous HIV‐1 Tat protein.

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Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil®): possible role in hypersensitivity reactions

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Current status of pH-sensitive liposomes in drug delivery

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Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy

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Direct Evidence That Polysorbate-80-Coated Poly(Butylcyanoacrylate) Nanoparticles Deliver Drugs to the CNS via Specific Mechanisms Requiring Prior Binding of Drug to the Nanoparticles

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Chemotherapy of glioblastoma in rats using doxorubicin‐loaded nanoparticles

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Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome–DNA complexes

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Two-Color Labeling of Oligonucleotide Arrays via Size-Selective Scattering of Nanoparticle Probes

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Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump.

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Accelerated Discovery of Synthetic Transfection Vectors: Parallel Synthesis and Screening of a Degradable Polymer Library

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Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging.

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

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Optical Nanosensors for Chemical Analysis inside Single Living Cells. 1. Fabrication, Characterization, and Methods for Intracellular Delivery of PEBBLE Sensors

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Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function

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Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy.

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Moving smaller in drug discovery and delivery

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Use of magnetic nanoparticles as nanosensors to probe for molecular interactions

Perez, J. M., Josephson, L., & Weissleder, R. (2004) · ChemBioChem · doi:10.1002/cbic.200300730 · Cited by 268 · see citing works

Gene transfer with modified polyethylenimines

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Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor-endothelial cells in vivo.

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The future of gene therapy

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Optimal Structure Requirements for Pluronic Block Copolymers in Modifying P-glycoprotein Drug Efflux Transporter Activity in Bovine Brain Microvessel Endothelial Cells

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Diacyllipid-Polymer Micelles as Nanocarriers for Poorly Soluble Anticancer Drugs

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Non-viral and hybrid vectors in human gene therapy: an update

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Dendritic Molecular Capsules for Hydrophobic Compounds

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Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic® block copolymers

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Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs.

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Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury

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Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

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Targeting adenovirus

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In vivo MRI of brain inflammation in human ischaemic stroke

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Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

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Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs

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Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

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Hybrid Virus−Polymer Materials. 1. Synthesis and Properties of PEG-Decorated Cowpea Mosaic Virus

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Probing the structural and molecular diversity of tumor vasculature

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Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice

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Self-assembling complexes for gene delivery : from laboratory to clinical trial

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Sustained Cytoplasmic Delivery of Drugs with Intracellular Receptors Using Biodegradable Nanoparticles

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Seeing Within

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Inflexal®V a trivalent virosome subunit influenza vaccine: production

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The polyoxyethylene/polyoxypropylene block co‐polymer Poloxamer‐407 selectively redirects intravenously injected microspheres to sinusoidal endothelial cells of rabbit bone marrow

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Recognition by Macrophages and Liver Cells of Opsonized Phospholipid Vesicles and Phospholipid Headgroups

Moghimi, S. M., & Hunter, A. C. (2001) · Pharmaceutical Research · doi:10.1023/a:1011054123304 · Cited by 161 · see citing works

Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity

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Enzymatic Release of Antitumor Ether Lipids by Specific Phospholipase A2Activation of Liposome-Forming Prodrugs

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Solution Structures and Integrin Binding Activities of an RGD Peptide with Two Isomers

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Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress

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Toxicogenomics of Non-viral Vectors for Gene Therapy: A Microarray Study of Lipofectin- and Oligofectamine-induced Gene Expression Changes in Human Epithelial Cells

Omidi, Y., Hollins, A. J., Benboubetra, M., Drayton, R. M., Benter, I. F., & Akhtar, S. (2003) · Journal of drug targeting · doi:10.1080/10611860310001636908 · Cited by 152 · see citing works

PEGylation of microspheres generates a heterogeneous population of particles with differential surface characteristics and biological performance

Gbadamosi, J. K., Hunter, A. C., & Moghimi, S. M. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)03710-9 · Cited by 150 · see citing works

Cationic Lipid Vectors for Plasmid DNA Delivery

Hirko, A. C., Tang, F., & Hughes, J. A. (2003) · Current Medicinal Chemistry · doi:10.2174/0929867033457412 · Cited by 150 · see citing works

Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis

Metselaar, J. M., van den Berg, W. B., Holthuysen, A. E. M., Wauben, M. H. M., Storm, G., & van Lent, P. L. E. M. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2003.009944 · Cited by 149 · see citing works

Formation of complement-activating particles in aqueous solutions of Taxol: possible role in hypersensitivity reactions

Szebeni, J., Alving, C. R., Sávay, S., Barenholz, Y., Priev, A., Danino, D., & Talmon, Y. (2001) · International Immunopharmacology · doi:10.1016/s1567-5769(01)00006-6 · Cited by 145 · see citing works

Lighting Up Cells with Quantum Dots

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Complement Activation-Related Pseudoallergy Caused by Liposomes, Micellar Carriers of Intravenous Drugs, and Radiocontrast Agents

Szebeni, J. (2001) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v18.i6.50 · Cited by 143 · see citing works

Comparison of ultrasmall particles of iron oxide (USPIO)-enhanced T2-weighted, conventional T2-weighted, and gadolinium-enhanced T1-weighted MR images in rats with experimental autoimmune encephalomyelitis.

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Pharmacological studies of cisplatin encapsulated in long-circulating liposomes in mouse tumor models

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Secreted phospholipase A2 as a new enzymatic trigger mechanism for localised liposomal drug release and absorption in diseased tissue

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An essential relationship between ATP depletion and chemosensitizing activity of Pluronic® block copolymers

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Subcutaneous and intravenous delivery of diagnostic agents to the lymphatic system: applications in lymphoscintigraphy and indirect lymphography

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Tuftsin-bearing liposomes in treatment of macrophage-based infections

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Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): A strategy for vascular immunotargeting of drugs

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Infarction of solid Hodgkin's tumors in mice by antibody-directed targeting of tissue factor to tumor vasculature.

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Structure and dynamics of the fenestrae-associated cytoskeleton of rat liver sinusoidal endothelial cells

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Expression of the β-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions

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Causative factors behind poloxamer 188 (Pluronic F68, Flocor™)-induced complement activation in human sera

Moghimi, S. M., Hunter, A. C., Dadswell, C., Sávay, S., Alving, C. R., & Szebeni, J. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.02.005 · Cited by 120 · see citing works

Aberrant vascular architecture in tumors and its importance in drug-based therapies

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Biophysical mechanisms of phospholipase A2 activation and their use in liposome‐based drug delivery

Jørgensen, K., Davidsen, J. R., & Mouritsen, O. G. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)03408-7 · Cited by 116 · see citing works

Dendritic Polyamines: Simple Access to New Materials with Defined Treelike Structures for Application in Nonviral Gene Delivery

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pDMAEMA is internalised by endocytosis but does not physically disrupt endosomes

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The effect of phagocytosis of poly( L ‐lactic acid) fragments on cellular morphology and viability

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Microparticles and Nanoparticles as Delivery Systems for DNA Vaccines

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1364. Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors

Haviv, Y. S., Blackwell, J. L., Kanerva, A., Nagi, P. A., Krasnykh, V. N., Dmitriev, I. P., Wang, M., Naito, S., Lei, X., Hemminki, A., et al. (2002) · Molecular Therapy · doi:10.1016/s1525-0016(16)44194-8 · Cited by 104 · see citing works

Chemical camouflage of nanospheres with a poorly reactive surface: towards development of stealth and target-specific nanocarriers

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Block Copolymer Micelles for the Encapsulation and Delivery of Amphotericin B

Lavasanifar, A., Samuel, J., Sattari, S., & Kwon, G. S. (2002) · Pharmaceutical Research · doi:10.1023/a:1015127225021 · Cited by 96 · see citing works

Drug targeting to specific vascular sites

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Application of Nanoparticle Technology for the Prevention of Restenosis After Balloon Injury in Rats

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MR imaging of murine arthritis using ultrasmall superparamagnetic iron oxide particles☆

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Therapeutic synthetic polymers: a game of Russian roulette?

Hunter, A. C., & Moghimi, S. M. (2002) · Drug Discovery Today · doi:10.1016/s1359-6446(02)02444-3 · Cited by 83 · see citing works

Long-circulating vectors for the systemic delivery of genes.

Fenske, D. B., MacLachlan, I., & Cullis, P. R. (2001) · PubMed · Cited by 82 · see citing works

Micelles from polyethylene glycol/phosphatidylethanolamine conjugates for tumor drug delivery

Lukyanov, A. N. (2003) · Journal of Controlled Release · doi:10.1016/s0168-3659(03)00217-7 · Cited by 78 · see citing works

Optical nanosensors for chemical analysis inside single living *cells.

Clark, H. A. (1999) · Deep Blue (University of Michigan) · Cited by 78 · see citing works

Synergistic permeability enhancing effect of lysophospholipids and fatty acids on lipid membranes

Davidsen, J. R., Mouritsen, O. G., & Jørgensen, K. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(02)00461-3 · Cited by 75 · see citing works

Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model

Alves‐Rosa, F., Stanganelli, C., Cabrera, J., van Rooijen, N., Palermo, M. S., & Isturiz, M. A. (2000) · Blood · doi:10.1182/blood.v96.8.2834 · Cited by 74 · see citing works

Modulation of lymphatic distribution of subcutaneously injected poloxamer 407‐coated nanospheres: the effect of the ethylene oxide chain configuration

Moghimi, S. M. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00273-4 · Cited by 72 · see citing works

Novel Method of Greatly Enhanced Delivery of Liposomes to Lymph Nodes

Phillips, W. T., Klipper, R. W., & Goins, B. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38903-7 · Cited by 71 · see citing works

Systemic Depletion of Macrophages by Liposomal Bisphosphonates Reduces Neointimal Formation Following Balloon-Injury in the Rat Carotid Artery

Danenberg, H. D., Fishbein, I., Epstein, H., et al. (2003) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200311000-00014 · Cited by 71 · see citing works

Lipid–protamine–DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses

Dileo, J., Banerjee‬‬‬‬‬‬‬‬‬, R., Whitmore, M., et al. (2003) · Molecular Therapy · doi:10.1016/s1525-0016(03)00064-9 · Cited by 69 · see citing works

Pig islet xenograft rejection is markedly delayed in macrophage‐depleted mice: a study in streptozotocin diabetic animals

Wu, G. S., Korsgren, O., Zhang, J., et al. (2000) · Xenotransplantation · doi:10.1034/j.1399-3089.2000.00071.x · Cited by 69 · see citing works

Lipid-based formulations of amphotericin B

Veerareddy, P. R., & Vobalaboina, V. (2004) · Drugs of today · doi:10.1358/dot.2004.40.2.799425 · Cited by 68 · see citing works

pH-Triggered Microparticles for Peptide Vaccination

Haining, W. N., Anderson, D. G., Little, S. R., von Berwelt-Baildon, M. S., Cardoso, A. A., Alves, P. M. S., Kosmatopoulos, K., Nadler, L. M., Langer, R., & Kohane, D. S. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.4.2578 · Cited by 68 · see citing works

Cellular Distribution of Nonionic Micelles

Moghimi, S. M., Hunter, A. C., Murray, J. C., & Szewczyk, A. M. (2004) · Science · doi:10.1126/science.303.5658.626 · Cited by 61 · see citing works

Cell‐selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting

Scherpereel, A., Wiewrodt, R. G., Christofidou‐Solomidou, M., et al. (2001) · The FASEB Journal · doi:10.1096/fj.00-0022com · Cited by 56 · see citing works

Targeting dendritic cells for priming cellular immune responses

Gogolák, P., Réthi, B., Hajas, G., & Rajnavölgyi, É. (2003) · Journal of Molecular Recognition · doi:10.1002/jmr.650 · Cited by 54 · see citing works

Differential Gene Expression Profile between PC-14 Cells Treated with Free Cisplatin and Cisplatin-Incorporated Polymeric Micelles

Nishiyama, N., Koizumi, F., Okazaki, S., Matsumura, Y., Nishio, K., & Kataoka, K. (2003) · Bioconjugate Chemistry · doi:10.1021/bc025555t · Cited by 49 · see citing works

Control of molecular polymorphisms by a structured carbohydrate / ceramic delivery vehicle — aquasomes

Kossovsky, N., Gelman, A., Rajguru, S., et al. (1996) · Journal of Controlled Release · doi:10.1016/0168-3659(95)00169-7 · Cited by 45 · see citing works

Development of a specific system for targeting protein to metallophilic macrophages

Taylor, P. R., ZAMZE, S. E., Stillion, R. J., Wong, S. Y. C., Gordon, S., & Martínez‐Pomares, L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308490100 · Cited by 45 · see citing works

Peptide-Retargeted Adenovirus Encoding a Tissue Inhibitor of Metalloproteinase-1 Decreases Restenosis after Intravascular Gene Transfer

Turunen, M. P., Puhakka, H. L., Koponen, J. K., et al. (2002) · Molecular Therapy · doi:10.1006/mthe.2002.0668 · Cited by 44 · see citing works

Immunotargeting of glucose oxidase to endothelium in vivo causes oxidative vascular injury in the lungs

Christofidou‐Solomidou, M., Pietra, G. G., Solomides, C., Arguiris, E., Harshaw, D. W., FitzGerald, G. A., Albelda, S. Μ., & Muzykantov, V. R. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.278.4.l794 · Cited by 37 · see citing works

Cytosolic Delivery of Viral Nucleoprotein by Listeriolysin O-Liposome Induces Enhanced Specific Cytotoxic T Lymphocyte Response and Protective Immunity

Mandal, M., Kawamura, K. S., Wherry, E. J., et al. (2003) · Molecular Pharmaceutics · doi:10.1021/mp034021m · Cited by 32 · see citing works

Lipid formulations of amphotericin B preserve and stabilize renal function in HSCT recipients

Miller, C. B., Waller, E. K., Klingemann, H.-G., et al. (2004) · Bone Marrow Transplantation · doi:10.1038/sj.bmt.1704408 · Cited by 27 · see citing works

Cytokines in mice treated with amphotericin B-intralipid

Shadkchan, Y., Keisari, Y., & Segal, E. (2004) · Medical Mycology · doi:10.1080/13693780310001624583 · Cited by 20 · see citing works

Lipopolycationic Telomers for Gene Transfer: Synthesis and Evaluation of Their in Vitro Transfection Efficiency

Verderone, G., Craynest, N. V., Boussif, O., et al. (2000) · Journal of Medicinal Chemistry · doi:10.1021/jm9911579 · Cited by 20 · see citing works

Endothelial Cells as Therapeutic Targets in Cancer: New Biology and Novel Delivery Systems

Murray, J. C., & Moghimi, S. M. (2003) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v20.i23.20 · Cited by 15 · see citing works

Posters

Murray, J., Moghimi, S., Hunter, A., et al. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6601928 · Cited by 4 · see citing works

Untitled work

Tsuchihashi (2000) · doi:10.1002/1521-4141(200006)30:6

Untitled work

Atsumi (2000) · doi:10.1002/1529-0131(200009)43:9

Nanomaterials and nanoparticles: Sources and toxicity

Buzea, C., Pacheco, I. I., & Robbie, K. (2007) · Biointerphases · doi:10.1116/1.2815690 · Cited by 3,789 · see citing works

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

Maeda, H., Nakamura, H., & Fang, J. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.002 · Cited by 2,376 · see citing works

New-Concept Chemotherapy by Nanoparticles of Biodegradable Polymers: Where Are We Now?

Feng, S.-S. (2006) · Nanomedicine · doi:10.2217/17435889.1.3.297 · Cited by 1,951 · see citing works

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

Salvati, A., Pitek, A. S., Monopoli, M. P., Prapainop, K., Bombelli, F. B., Hristov, D. R., Kelly, P. M., Åberg, C., Mahon, E., & Dawson, K. A. (2013) · Nature Nanotechnology · doi:10.1038/nnano.2012.237 · Cited by 1,912 · see citing works

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

Walkey, C. D., & Chan, W. C. W. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15233e · Cited by 1,758 · see citing works

Physical approaches to biomaterial design

Mitragotri, S., & Lahann, J. (2009) · Nature Materials · doi:10.1038/nmat2344 · Cited by 1,445 · see citing works

Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems

Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J. S., Chin, S.-F., Sherry, A. D., Boothman, D. A., & Gao, J. (2006) · Nano Letters · doi:10.1021/nl061412u · Cited by 1,238 · see citing works

The transferrin receptor and the targeted delivery of therapeutic agents against cancer

Daniels, T. R., Bernabeu, E., Rodríguez, J. A., Patel, S., Kozman, M., Chiappetta, D. A., Holler, E., Ljubimova, J. Y., Helguera, G., & Penichet, M. L. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.07.016 · Cited by 807 · see citing works

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645 · see citing works

Polymeric nanomedicine for cancer therapy

Park, J. H., Lee, S., Kim, J.-H., Park, K., Kim, K., & Kwon, I. C. (2008) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.09.003 · Cited by 506 · see citing works

Perspectives and opportunities for nanomedicine in the management of atherosclerosis

Lobatto, M. E., Fuster, V., Fayad, Z. A., & Mulder, W. J. M. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3578 · Cited by 423 · see citing works

Drug nanocrystals: in vivo performances.

Gao, L., Liu, G., Ma, J., Wang, X., Zhou, L., & Li, X. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.013 · Cited by 347 · see citing works

Clinical toxicities of nanocarrier systems.

Vega-Villa, K. R., Takemoto, J. K., Yáñez, J. A., Remsberg, C. M., Forrest, M. L., & Davies, N. M. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.11.007 · Cited by 325 · see citing works

Biological applications of X-ray fluorescence microscopy: exploring the subcellular topography and speciation of transition metals

Fahrni, C. J. (2007) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2007.02.039 · Cited by 297 · see citing works

Micelles structure development as a strategy to improve smart cancer therapy

Hanafy, N., El-Kemary, M., & Leporatti, S. (2018) · Cancers · doi:10.3390/cancers10070238 · Cited by 287 · see citing works

Pharmaceutical nanotechnology: from the bench to the market

Mazayen, Z. M., Ghoneim, A. M., Elbatanony, R. S., Basalious, E. B., & Bendas, E. R. (2022) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-022-00400-0 · Cited by 208 · see citing works

Fate of micelles and quantum dots in cells

Maysinger, D., Lovrić, J., Eisenberg, A., & Savić, R. (2007) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2006.08.011 · Cited by 160 · see citing works

PEGylated nanomedicines: recent progress and remaining concerns

Vllasaliu, D., Fowler, R., & Stolnik, S. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2014.866651 · Cited by 137 · see citing works

The formulation of nanomedicines for treating tuberculosis

Costa, A., Pinheiro, M., Magalhães, J., Ribeiro, R., Seabra, V., Reis, S., & Sarmento, B. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.04.012 · Cited by 123 · see citing works

Tumor Specific Delivery and Therapy by Double-Targeted Nanostructured Lipid Carriers with Anti-VEGFR-2 Antibody

Liu, D., Liu, F., Liu, Z., Wang, L., & Zhang, N. (2011) · Molecular Pharmaceutics · doi:10.1021/mp200402e · Cited by 108 · see citing works

Nanoparticle-Mediated Drug Delivery System for Cardiovascular Disease

Matoba, T., & Egashira, K. (2014) · International Heart Journal · doi:10.1536/ihj.14-150 · Cited by 83 · see citing works

Functional biomimetic nanoparticles for drug delivery and theranostic applications in cancer treatment

Li, L., Wang, J., Kong, H., Zeng, Y., & Liu, G. (2018) · Science and Technology of Advanced Materials · doi:10.1080/14686996.2018.1528850 · Cited by 71 · see citing works

Synthetic Microvascular Networks for Quantitative Analysis of Particle Adhesion

Prabhakarpandian, B., Pant, K., Scott, R. C., Patillo, C. B., Irimia, D., Kiani, M. F., & Sundaram, S. (2008) · Biomedical Microdevices · doi:10.1007/s10544-008-9170-y · Cited by 68 · see citing works

LHRH-targeted nanogels as a delivery system for cisplatin to ovarian cancer

Nukolova, N. V., Oberoi, H. S., Zhao, Y., Chekhonin, V. P., Kabanov, A. V., & Bronich, T. K. (2013) · Molecular Pharmaceutics · doi:10.1021/mp4003688 · Cited by 63 · see citing works

Tissue Engineering and Targeted Drug Delivery in Cardiovascular Disease: The Role of Polymer Nanocarrier for Statin Therapy

Montelione, N., Loreni, F., Nenna, A., Catanese, V., Scurto, L., Ferrisi, C., Jawabra, M., Gabellini, T., Codispoti, F. A., Spinelli, F., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11030798 · Cited by 30 · see citing works

Targeting of herbal bioactives through folate receptors: a novel concept to enhance intracellular drug delivery in cancer therapy

Gupta, A., Kaur, C. D., Saraf, S., & Saraf, S. (2017) · Journal of Receptors and Signal Transduction · doi:10.3109/10799893.2016.1147581 · Cited by 27 · see citing works

Antibody modified Bovine Serum Albumin microspheres for targeted delivery of anticancer agent Gemcitabine

Grinberg, O., Gedanken, A., Mukhopadhyay, D., & Patra, C. R. (2013) · Polymers for Advanced Technologies · doi:10.1002/pat.3081 · Cited by 16 · see citing works

Particle characterisation in drug delivery

Vllasaliu, D., & Singh, I. S. (2014) · Lincoln Repository (University of Lincoln) · Cited by 2 · see citing works

Smart Nanoparticles for Drug Delivery Application: Development of Versatile Nanocarrier Platforms in Biotechnology and Nanomedicine

Lombardo, D., Kiselev, M. A., & Caccamo, M. T. (2019) · Journal of Nanomaterials · doi:10.1155/2019/3702518 · Cited by 864 · see citing works

Magnetic iron oxide nanoparticles for drug delivery: applications and characteristics

Vangijzegem, T., Stanicki, D., & Laurent, S. (2018) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2019.1554647 · Cited by 553 · see citing works

Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

Maeki, M., Kimura, N., Sato, Y., Harashima, H., & Tokeshi, M. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.03.008 · Cited by 320 · see citing works

Potentials and emerging trends in nanopharmacology

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