The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Steroid Control of Longevity in Drosophila melanogaster
Abstract
Ecdysone, the major steroid hormone of Drosophila melanogaster , is known for its role in development and reproduction. Flies that are heterozygous for mutations of the ecdysone receptor exhibit increases in life-span and resistance to various stresses, with no apparent deficit in fertility or activity. A mutant involved in the biosynthesis of ecdysone displays similar effects, which are suppressed by feeding ecdysone to the flies. These observations demonstrate the importance of the ecdysone hormonal pathway, a new player in regulating longevity.
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Cites
The juvenile hormones: historical facts and speculations on future research directions
Gilbert, L. I., A. Granger, N., & Roe, R. M. (2000) · Insect Biochemistry and Molecular Biology · doi:10.1016/s0965-1748(00)00034-5 · Cited by 436
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Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
The plasticity of aging: insights from long-lived mutants
Kenyon, C. (2005) · Cell · doi:10.1016/j.cell.2005.02.002 · Cited by 1,338
Sex and Death: What Is the Connection?
Partridge, L., Gems, D., & Withers, D. J. (2005) · Cell · doi:10.1016/j.cell.2005.01.026 · Cited by 402
Endocrine regulation of ageing
Russell, S. J., & Kahn, C. R. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2234 · Cited by 356
The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila
Liu, N., Landreh, M., Cao, K., Abe, M., Hendriks, G.-J., Kennerdell, J. R., Zhu, Y., Wang, L.-S., & Bonini, N. M. (2012) · Nature · doi:10.1038/nature10810 · Cited by 356
Metadata
- Authors
- Simon, A. F., Shih, C., Mack, A., & Benzer, S.
- Venue
- Science
- Published
- 2003-02-28
- Volume
- 299
- Issue
- 5611
- Pages
- 1407-1410
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2121767856
- Cited by
- 265
- References
- 1
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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