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Role of the Arabidopsis Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling

Moore, Brandon, Zhou, Li, Rolland, Filip, Hall, Qi, Cheng, Wan-Hsing, Liu, Yan-Xia, Hwang, Ildoo, Jones, Tamara, Sheen, Jen·2003·Science

Abstract

Glucose modulates many vital processes in photosynthetic plants. Analyses of Arabidopsis glucose insensitive2 ( gin2 ) mutants define the physiological functions of a specific hexokinase (HXK1) in the plant glucose-signaling network. HXK1 coordinates intrinsic signals with extrinsic light intensity. HXK1 mutants lacking catalytic activity still support various signaling functions in gene expression, cell proliferation, root and inflorescence growth, and leaf expansion and senescence, thus demonstrating the uncoupling of glucose signaling from glucose metabolism. The gin2 mutants are also insensitive to auxin and hypersensitive to cytokinin. Plants use HXK as a glucose sensor to interrelate nutrient, light, and hormone signaling networks for controlling growth and development in response to the changing environment.

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Research works printed but not linked: 21

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Metadata

Authors
Moore, B., Zhou, L., Rolland, F., Hall, Q., Cheng, W.-H., Liu, Y.-X., Hwang, I., Jones, T., & Sheen, J.
Venue
Science
Published
2003-04-11
Volume
300
Issue
5617
Pages
332-336
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2015924572
Cited by
1,181
References
5
FWCI
58.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Role of the Arabidopsis Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling. https://app.cochat.ai/papers/10.1126/science.1080585
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Moore, B., Zhou, L., Rolland, F., Hall, Q., Cheng, W.-H., Liu, Y.-X., Hwang, I., Jones, T., & Sheen, J. (2003). Role of the Arabidopsis Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling. Science. https://doi.org/10.1126/science.1080585

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