The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Encoding Pheromonal Signals in the Accessory Olfactory Bulb of Behaving Mice
Abstract
Many mammalian species rely on pheromones-semiochemicals produced by other members of the same species-to communicate social status and reproductive readiness. To assess how the central nervous system integrates the complex repertoire of pheromones, we recorded from single neurons in the accessory olfactory bulb, a nucleus that processes pheromonal signals, of male mice engaged in natural behaviors. Neuronal firing was robustly modulated by physical contact with male and female conspecifics, with individual neurons activated selectively by specific combinations of the sex and strain of conspecifics. We infer that mammals encode social and reproductive information by integrating vomeronasal sensory activity specific to sex and genetic makeup.
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“This organization suggests that an important transformation of sensory information occurs in the AOB, from a segregated sampling system in the VNO to more integrated codes in the AOB (Luo et al., 2003; Meeks et al., 2010).”
From Neuronal Representation of Social Information in the Medial Amygdala of Awake Behaving Mice (2017) · cites this paper as Luo et al., 2003
In the citing paper
“Intriguingly, selective inhibition also shapes social discrimination in the AOB (Luo et al., 2003; Meeks et al., 2010).”
From Neuronal Representation of Social Information in the Medial Amygdala of Awake Behaving Mice (2017) · cites this paper as Luo et al., 2003
Citations
Cites
Combinatorial Receptor Codes for Odors
Malnic, B., Hirono, J., Sato, T., & Buck, L. B. (1999) · Cell · doi:10.1016/s0092-8674(00)80581-4 · Cited by 2,302
Visualizing an Olfactory Sensory Map
Mombaerts, P., Wang, F., Dulac, C. G., Chao, S. K., Nemes, A., Mendelsohn, M. M., Edmondson, J., & Axel, R. (1996) · Cell · doi:10.1016/s0092-8674(00)81387-2 · Cited by 1,992
A novel family of genes encoding putative pheromone receptors in mammals
Dulac, C., & Axel, R. (1995) · Cell · doi:10.1016/0092-8674(95)90161-2 · Cited by 1,001
Loss of Sex Discrimination and Male-Male Aggression in Mice Deficient for TRP2
Stowers, L., Holy, T. E., Meister, M., Dulac, C. G., & Koentges, G. (2002) · Science · doi:10.1126/science.1069259 · Cited by 880
An Exteroceptive Block to Pregnancy in the Mouse
Bruce, H. M. (1959) · Nature · doi:10.1038/184105a0 · Cited by 746
The Organization and Function of the Vomeronasal System
Halpern, M. (1987) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.10.030187.001545 · Cited by 732
Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb.
Yokoi, M., Mori, K., & Nakanishi, S. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.8.3371 · Cited by 614
Individual recognition in mice mediated by major urinary proteins
Hurst, J. L., Payne, C. E., Nevison, C. M., Marie, A. D., Humphries, R. E., Robertson, D. H. L., Cavaggioni, A., & Beynon, R. J. (2001) · Nature · doi:10.1038/414631a · Cited by 605
A New Multigene Family of Putative Pheromone Receptors
Ryba, N. J. P., & Tirindelli, R. (1997) · Neuron · doi:10.1016/s0896-6273(00)80946-0 · Cited by 598
Sparse Population Coding of Faces in the Inferotemporal Cortex
Young, M. P., & Yamane, S. (1992) · Science · doi:10.1126/science.1598577 · Cited by 595
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- E. S. Albone Mammalian Semiochemistry: The Investigation of Chemical Signals Between Mammals (Wiley New York 1984).
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Genes and ligands for odorant, vomeronasal and taste receptors
Mombaerts, P. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1365 · Cited by 693
“, its neurons respond to molecules other than pheromones, but it remains to be established whether these molecules are physiologically relevant stimul”
BackgroundMolecular detection of pheromone signals in mammals: from genes to behaviour
Dulac, C. G., & Torello, A. T. (2003) · Nature reviews. Neuroscience · doi:10.1038/nrn1140 · Cited by 662
“How is pheromonal information encoded in the mitral cells? Using an array of electrodes implanted in the mouse AOB, Luo and colleagues recently recorded mitral cell activity in freely moving mic”
Structure and function of the vomeronasal system: an update
Halpern, M. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00103-5 · Cited by 639
MHC Class I Peptides as Chemosensory Signals in the Vomeronasal Organ
Leinders‐Zufall, T., Brennan, P., Widmayer, P., Prashanth Chandramani, S., Maul‐Pavicic, A., Jäger, M., Li, X.-H., Breer, H., Zufall, F., & Boehm, T. L. J. (2004) · Science · doi:10.1126/science.1102818 · Cited by 608
Neural circuit mechanisms of social behavior
Chen, P., & Hong, W. (2018) · Neuron · doi:10.1016/j.neuron.2018.02.026 · Cited by 527
“…initial investigation of a conspecific and is maintained for a short period of time after the conspecific has been removed (Hashikawa et al., 2016; Luo et al., 2003), suggesting that activity in the AOB changes with duration of investigation, and is not strictly correlated with the presence of…”
Metadata
- Authors
- Luo, M., Fee, M. S., & Katz, L. C.
- Affiliations
- Howard Hughes Medical Institute (US)
- Alcatel-Lucent (France) (FR)
- Corresponding author
- Luo, Minmin
- Venue
- Science
- Published
- 2003-02-21
- Volume
- 299
- Issue
- 5610
- Pages
- 1196-1201
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2040886375
- Cited by
- 365
- References
- 47
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 15 · 2023: 9 · 2022: 7 · 2021: 10 · 2020: 9 · 2019: 6 · 2018: 16 · 2017: 23 · 2016: 15 · 2015: 18 · 2014: 15 · 2013: 15 · 2012: 12
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Keywords
- pheromones, vomeronasal system, accessory olfactory bulb, single-unit recording, social communication, reproductive status, sex-specific responses, genetic strain differences, natural behavior
- MeSH terms
- Action Potentials, Animals, Anal Canal, Behavior, Animal, Cues, Electrodes, Implanted, Face, Female, Genitalia, Male, Mice, Inbred BALB C, Mice, Inbred CBA, Mice, Inbred C57BL, Microelectrodes, Mouth, Neural Inhibition, Neurons, Neurons, Afferent, Odorants, Olfactory Bulb, Olfactory Pathways, Pheromones, Sex Characteristics, Smell, Species Specificity, Vomeronasal Organ, Mice
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