The DOI matches its Crossref record.
A B Cell-Based Sensor for Rapid Identification of Pathogens
Abstract
We report the use of genetically engineered cells in a pathogen identification sensor. This sensor uses B lymphocytes that have been engineered to emit light within seconds of exposure to specific bacteria and viruses. We demonstrated rapid screening of relevant samples and identification of a variety of pathogens at very low levels. Because of its speed, sensitivity, and specificity, this pathogen identification technology could prove useful for medical diagnostics, biowarfare defense, food- and water-quality monitoring, and other applications.
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Citations
Cited by
Banerjee, P., Lenz, D., Robinson, J. P., Rickus, J. L., & Bhunia, A. K. (2008) · Laboratory Investigation · doi:10.1038/labinvest.3700703 · Cited by 97
Whole-cell biochips for bio-sensing: integration of live cells and inanimate surfaces
Ben-Yoav, H., Melamed, S., Freeman, A., Shacham-Diamand, Y., & Belkin, S. (2011) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2010.532767 · Cited by 52
Metadata
- Authors
- Rider, T. H., Petrovick, M. S., Nargi, F. E., Harper, J. D., Schwoebel, E. D., Mathews, R. H., Blanchard, D. J., Bortolin, L. T., Young, A. M., Chen, J., & Hollis, M. A.
- Venue
- Science
- Published
- 2003-07-11
- Volume
- 301
- Issue
- 5630
- Pages
- 213-215
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2138830274
- Cited by
- 267
- References
- 0
- FWCI
- 13.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A B Cell-Based Sensor for Rapid Identification of Pathogens. https://app.cochat.ai/papers/10.1126/science.1084920
- The paper
- Rider, T. H., Petrovick, M. S., Nargi, F. E., Harper, J. D., Schwoebel, E. D., Mathews, R. H., Blanchard, D. J., Bortolin, L. T., Young, A. M., Chen, J., & Hollis, M. A. (2003). A B Cell-Based Sensor for Rapid Identification of Pathogens. Science. https://doi.org/10.1126/science.1084920
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
