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Biosynthesis of the Food and Cosmetic Plant Pigment Bixin (Annatto)
Abstract
Bixin, also known as annatto, is a seed-specific pigment widely used in foods and cosmetics since pre-Columbian times. We show that three genes from Bixa orellana , native to tropical America, govern bixin biosynthesis. These genes code for lycopene cleavage dioxygenase, bixin aldehyde dehydrogenase, and norbixin carboxyl methyltransferase, which catalyze the sequential conversion of lycopene into bixin. Introduction of these three genes in Escherichia coli engineered to produce lycopene induced bixin synthesis, thus expanding the supply of this economically important plant product.
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Cited by
Biosynthesis of plant pigments: anthocyanins, betalains and carotenoids
Tanaka, Y., Sasaki, N., & Ohmiya, A. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03447.x · Cited by 2,434
Carotenoid Metabolism in Plants
Nisar, N., Li, L., Lu, S., Khin, N. C., & Pogson, B. J. (2015) · Molecular Plant · doi:10.1016/j.molp.2014.12.007 · Cited by 1,255
Advances in Fruit Aroma Volatile Research
El Hadi, M., Zhang, F.-J., Wu, F.-F., Zhou, C.-H., & Tao, J. (2013) · Molecules · doi:10.3390/molecules18078200 · Cited by 836
Carotenoids and their cleavage products: Biosynthesis and functions
Walter, M. H., & Strack, D. (2011) · Natural Product Reports · doi:10.1039/c0np00036a · Cited by 580
Simkin, A. J., Kapoor, L., Doss, C. G. P., Hofmann, T. A., Lawson, T., & Ramamoorthy, S. (2022) · Photosynthesis Research · doi:10.1007/s11120-021-00892-6 · Cited by 561
Metadata
- Authors
- Bouvier, F., Dogbo, O., & Camara, B.
- Venue
- Science
- Published
- 2003-06-27
- Volume
- 300
- Issue
- 5628
- Pages
- 2089-2091
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2085123761
- Cited by
- 253
- References
- 0
- FWCI
- 4.18
- Type
- journal article
- Language
- en
- Open access
- closed
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