The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Elastic Behavior of Cross-Linked and Bundled Actin Networks
Abstract
Networks of cross-linked and bundled actin filaments are ubiquitous in the cellular cytoskeleton, but their elasticity remains poorly understood. We show that these networks exhibit exceptional elastic behavior that reflects the mechanical properties of individual filaments. There are two distinct regimes of elasticity, one reflectingbendingof single filaments and a second reflectingstretchingof entropic fluctuations of filament length. The mechanical stiffness can vary by several decades with small changes in cross-link concentration, and can increase markedly upon application of external stress. We parameterize the full range of behavior in a state diagram and elucidate its origin with a robust model.
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Cites
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Entropic Elasticity of λ-Phage DNA
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Self-citationElasticity of Stiff Polymer Networks
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Self-citationThe mechanical properties of actin gels. Elastic modulus and filament motions.
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Cited by
Effects of extracellular matrix viscoelasticity on cellular behaviour
Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature · doi:10.1038/s41586-020-2612-2 · Cited by 2,224
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
Wood, J. G., Rogina, B., Lavu, S., Howitz, K., Helfand, S. L., Tatar, M., & Sinclair, D. (2004) · Nature · doi:10.1038/nature02789 · Cited by 1,868
Biomechanics and biophysics of cancer cells☆
SURESH, S. (2007) · Acta Biomaterialia · doi:10.1016/j.actbio.2007.04.002 · Cited by 1,284
Universal physical responses to stretch in the living cell
Trepat, X., Deng, L., An, S. S., Navajas, D., Tschumperlin, D. J., Gerthoffer, W. T., Butler, J. P., & Fredberg, J. J. (2007) · Nature · doi:10.1038/nature05824 · Cited by 699
Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis
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Metadata
- Authors
- Gardel, M. L., Shin, J. H., MacKintosh, F. C., Mahadevan, L., Matsudaira, P., & Weitz, D. A.
- Venue
- Science
- Published
- 2004-05-28
- Volume
- 304
- Issue
- 5675
- Pages
- 1301-1305
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2117425975
- Cited by
- 1,256
- References
- 19
- FWCI
- 14.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gardel, M. L., Shin, J. H., MacKintosh, F. C., Mahadevan, L., Matsudaira, P., & Weitz, D. A. (2004). Elastic Behavior of Cross-Linked and Bundled Actin Networks. Science. https://doi.org/10.1126/science.1095087
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
