The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites
Abstract
Vesicular glutamate transporters (VGLUTs) 1 and 2 show a mutually exclusive distribution in the adult brain that suggests specialization for synapses with different properties of release. Consistent with this distribution, inactivation of the VGLUT1 gene silenced a subset ofexcitatory neurons in the adult. However, the same cell populations exhibited VGLUT1-independent transmission early in life. Developing hippocampal neurons transiently coexpressed VGLUT2 and VGLUT1 at distinct synaptic sites with different short-term plasticity. The loss of VGLUT1 also reduced the reserve pool of synaptic vesicles. Thus, VGLUT1 plays an unanticipated role in membrane trafficking at the nerve terminal.
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Cites
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
Verhage, M., Maia, A. S., Plomp, J. J., Brussaard, A. B., Heeroma, J. H., Vermeer, H., Toonen, R. F., Hammer, R. E., van den, T. K., Berg, et al. (2000) · Science · doi:10.1126/science.287.5454.864 · Cited by 1,428
The Expression of Vesicular Glutamate Transporters Defines Two Classes of Excitatory Synapse
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Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter
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Self-citationMunc13-1 is essential for fusion competence of glutamatergic synaptic vesicles
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Essential functions of synapsins I and II in synaptic vesicle regulation
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A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons
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Cited by
The synapsins: Key actors of synapse function and plasticity
Cesca, F., Baldelli, P., Valtorta, F., & Benfenati, F. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.04.006 · Cited by 654
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A shared vesicular carrier allows synaptic corelease of GABA and glycine
Wojcik, S. M., Katsurabayashi, S., Guillemin, I., Friauf, E., Rosenmund, C., Brose, N., & Rhee, J.-S. (2006) · Neuron · doi:10.1016/j.neuron.2006.04.016 · Cited by 374
Presynaptic Regulation of Quantal Size by the Vesicular Glutamate Transporter VGLUT1
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Overview of glutamatergic neurotransmission in the nervous system
Niciu, M. J., Kelmendi, B., & Sanacora, G. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.08.008 · Cited by 329
Metadata
- Authors
- Fremeau, R. T., Kam, K., Qureshi, T., Johnson, J., Copenhagen, D. R., Storm-Mathisen, J., Chaudhry, F. A., Nicoll, R. A., & Edwards, R. H.
- Venue
- Science
- Published
- 2004-06-18
- Volume
- 304
- Issue
- 5678
- Pages
- 1815-1819
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2037718442
- Cited by
- 498
- References
- 27
- FWCI
- 10.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fremeau, R. T., Kam, K., Qureshi, T., Johnson, J., Copenhagen, D. R., Storm-Mathisen, J., Chaudhry, F. A., Nicoll, R. A., & Edwards, R. H. (2004). Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites. Science. https://doi.org/10.1126/science.1097468
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
