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Monodisperse Double Emulsions Generated from a Microcapillary Device
Abstract
Double emulsions are highly structured fluids consisting of emulsion drops that contain smaller droplets inside. Although double emulsions are potentially of commercial value, traditional fabrication by means of two emulsification steps leads to very ill-controlled structuring. Using a microcapillary device, we fabricated double emulsions that contained a single internal droplet in a core-shell geometry. We show that the droplet size can be quantitatively predicted from the flow profiles of the fluids. The double emulsions were used to generate encapsulation structures by manipulating the properties of the fluid that makes up the shell. The high degree of control afforded by this method and the completely separate fluid streams make this a flexible and promising technique.
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Cited by
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Physical approaches to biomaterial design
Mitragotri, S., & Lahann, J. (2009) · Nature Materials · doi:10.1038/nmat2344 · Cited by 1,445
25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine
Annabi, N., Tamayol, A., Uquillas, J. A., Akbari, M., Bertassoni, L. E., Cha, C., Camci‐Unal, G., Dokmeci, M. R., Peppas, N. A., & Khademhosseini, A. (2014) · Advanced Materials · doi:10.1002/adma.201303233 · Cited by 1,409
Dripping to Jetting Transitions in Coflowing Liquid Streams
Utada, A. S., Fernandez-Nieves, A., Stone, H. A., & Weitz, D. A. (2007) · Physical Review Letters · doi:10.1103/physrevlett.99.094502 · Cited by 965
Self-citationSynthesis of micro and nanostructures in microfluidic systems
Marre, S., & Jensen, K. F. (2010) · Chemical Society Reviews · doi:10.1039/b821324k · Cited by 734
Metadata
- Authors
- Utada, A. S., Lorenceau, E., Link, D. R., Kaplan, P. D., Stone, H. A., & Weitz, D. A.
- Venue
- Science
- Published
- 2005-04-22
- Volume
- 308
- Issue
- 5721
- Pages
- 537-541
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2088617194
- Cited by
- 2,248
- References
- 0
- FWCI
- 56.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- Utada, A. S., Lorenceau, E., Link, D. R., Kaplan, P. D., Stone, H. A., & Weitz, D. A. (2005). Monodisperse Double Emulsions Generated from a Microcapillary Device. Science. https://doi.org/10.1126/science.1109164
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