The DOI matches its Crossref record.
Cladosporium Avr2 Inhibits Tomato Rcr3 Protease Required for Cf-2 -Dependent Disease Resistance
Open accessAbstract
How plants recognize pathogens and activate defense is still mysterious. Direct interaction between pathogen avirulence (Avr) proteins and plant disease resistance proteins is the exception rather than the rule. During infection, Cladosporium fulvum secretes Avr2 protein into the apoplast of tomato leaves and, in the presence of the extracellular leucine-rich repeat receptor-like Cf-2 protein, triggers a hypersensitive response (HR) that also requires the extracellular tomato cysteine protease Rcr3. We show here that Avr2 binds and inhibits Rcr3 and propose that the Rcr3-Avr2 complex enables the Cf-2 protein to activate an HR.
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Cited by
Jones, J. D. G., & Dangl, J. L. (2006) · Nature · doi:10.1038/nature05286 · Cited by 13,177
Self-citationBoller, T., & Felix, G. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105346 · Cited by 3,387
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
Chisholm, S. T., Coaker, G., Day, B., & Staskawicz, B. J. (2006) · Cell · doi:10.1016/j.cell.2006.02.008 · Cited by 2,957
Fungal Effectors and Plant Susceptibility
Lo Presti, L., Lanver, D., Schweizer, G., Tanaka, S., Liang, L., Tollot, M., Zuccaro, A., Reissmann, S., & Kahmann, R. (2015) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-043014-114623 · Cited by 1,249
From Guard to Decoy: A New Model for Perception of Plant Pathogen Effectors
van der Hoorn, R. A. L., & Kamoun, S. (2008) · The Plant Cell · doi:10.1105/tpc.108.060194 · Cited by 784
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Metadata
- Authors
- Rooney, H. C. E., van't Klooster, J. W., van der Hoorn, R. A. L., Joosten, M. H. A. J., Jones, J. D. G., & de Wit, P. J. G. M.
- Venue
- Science
- Published
- 2005-06-17
- Volume
- 308
- Issue
- 5729
- Pages
- 1783-1786
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2164937876
- Cited by
- 501
- References
- 0
- FWCI
- 37.48
- Type
- journal article
- Language
- en
- Open access
- green
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- Rooney, H. C. E., van't Klooster, J. W., van der Hoorn, R. A. L., Joosten, M. H. A. J., Jones, J. D. G., & de Wit, P. J. G. M. (2005). Cladosporium Avr2 Inhibits Tomato Rcr3 Protease Required for Cf-2 -Dependent Disease Resistance. Science. https://doi.org/10.1126/science.1111404
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