The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments
Abstract
Organisms in fluctuating environments must constantly adapt their behavior to survive. In clonal populations, this may be achieved through sensing followed by response or through the generation of diversity by stochastic phenotype switching. Here we show that stochastic switching can be favored over sensing when the environment changes infrequently. The optimal switching rates then mimic the statistics of environmental changes. We derive a relation between the long-term growth rate of the organism and the information available about its fluctuating environment.
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Citations
Cites
Bacterial Persistence as a Phenotypic Switch
Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L., & Leibler, S. (2004) · Science · doi:10.1126/science.1099390 · Cited by 2,952
Self-citationPhenotypic switching and filamentation in Candida glabrata
Lachke, S. A., Joly, S., Daniels, K., & Soll, D. R. (2002) · Microbiology · doi:10.1099/00221287-148-9-2661 · Cited by 103
Cited by
Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
Raj, A., & van Oudenaarden, A. (2008) · Cell · doi:10.1016/j.cell.2008.09.050 · Cited by 2,593
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
Gupta, P. B., Fillmore, C. M., Jiang, G., Shapira, S. D., Tao, K., Kuperwasser, C., & Lander, E. S. (2011) · Cell · doi:10.1016/j.cell.2011.07.026 · Cited by 1,475
Noise in protein expression scales with natural protein abundance
Bar-Even, A., Paulsson, J., Maheshri, N., Carmi, M., O'Shea, E., Pilpel, Y., & Barkai, N. (2006) · Nature Genetics · doi:10.1038/ng1807 · Cited by 807
Flocculation, adhesion and biofilm formation in yeasts
Verstrepen, K. J., & Klis, F. M. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05072.x · Cited by 589
Adaptive prediction of environmental changes by microorganisms
Mitchell, A., Romano, G. H., Groisman, B., Yona, A., Dekel, E., Kupiec, M., Dahan, O., & Pilpel, Y. (2009) · Nature · doi:10.1038/nature08112 · Cited by 581
Metadata
- Authors
- Kussell, E., & Leibler, S.
- Venue
- Science
- Published
- 2005-09-23
- Volume
- 309
- Issue
- 5743
- Pages
- 2075-2078
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2043487490
- Cited by
- 1,356
- References
- 2
- FWCI
- 18.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kussell, E., & Leibler, S. (2005). Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments. Science. https://doi.org/10.1126/science.1114383
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
