The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
The Embryonic Vertebrate Heart Tube Is a Dynamic Suction Pump
Abstract
The embryonic vertebrate heart begins pumping blood long before the development of discernable chambers and valves. At these early stages, the heart tube has been described as a peristaltic pump. Recent advances in confocal laser scanning microscopy and four-dimensional visualization have warranted another look at early cardiac structure and function. We examined the movement of cells in the embryonic zebrafish heart tube and the flow of blood through the heart and obtained results that contradict peristalsis as a pumping mechanism in the embryonic heart. We propose a more likely explanation of early cardiac dynamics in which the pumping action results from suction due to elastic wave propagation in the heart tube.
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Citations
Cites
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis
Hove, J. R., Köster, R. W., Forouhar, A. S., Acevedo-Bolton, G., Fraser, S. E., & Gharib, M. (2003) · Nature · doi:10.1038/nature01282 · Cited by 997
Self-citationFashioning the vertebrate heart: earliest embryonic decisions
Fishman, M. C., & Chien, K. R. (1997) · Development · doi:10.1242/dev.124.11.2099 · Cited by 491
Zebrafish genetics and vertebrate heart formation
Stainier, D. Y. R. (2001) · Nature Reviews Genetics · doi:10.1038/35047564 · Cited by 427
Zebrafish--the Canonical Vertebrate
Fishman, M. C. (2001) · Science · doi:10.1126/science.1066652 · Cited by 218
Liebling, M., Forouhar, A. S., Gharib, M., et al. (2005) · Journal of Biomedical Optics · doi:10.1117/1.2061567 · Cited by 164
Self-citationCardiac patterning and morphogenesis in zebrafish
Yelon, D. L. (2001) · Developmental Dynamics · doi:10.1002/dvdy.1243 · Cited by 112
Experimental study of the behavior of a valveless impedance pump
Hickerson, A. I., Rinderknecht, D. G., & Gharib, M. (2005) · Experiments in Fluids · doi:10.1007/s00348-005-0946-z · Cited by 94
Self-citationExperimental study of the behavior of a valveless impedance pump
Hickerson, A. I., Rinderknecht, D. G., & Gharib, M. (2005) · Experiments in Fluids · doi:10.1007/s00348-005-0029-1 · Cited by 72
Self-citationBuckberg, G. D., Clemente, C., Cox, J. L., Coghlan, H. C., Castellà, M., Torrent-Guasp, F., & Gharib, M. (2001) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1053/stcs.2001.29956 · Cited by 70
Self-citation
Cited by
Mechanical control of tissue and organ development
Mammoto, T., & Ingber, D. E. (2010) · Development · doi:10.1242/dev.024166 · Cited by 850
Muscular Thin Films for Building Actuators and Powering Devices
Feinberg, A. W., Feigel, A., Shevkoplyas, S. S., Sheehy, S., Whitesides, G. M., & Parker, K. K. (2007) · Science · doi:10.1126/science.1146885 · Cited by 765
Glymphatic influx and clearance are accelerated by neurovascular coupling
Holstein-Rønsbo, S., Gan, Y., Giannetto, M. J., Rasmussen, M. K., Sigurdsson, B., Beinlich, F. R. M., Rose, L., Untiet, V., Hablitz, L. M., Kelley, D. H., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01327-2 · Cited by 248
Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development
Goetz, J. G., Steed, E., Ferreira, R. R., Roth, S., Ramspacher, C., Boselli, F., Charvin, G., Liebling, M., Wyart, C., Schwab, Y., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.01.032 · Cited by 219
Self-citationMechanical regulation of cardiac development
Lindsey, S. E. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00318 · Cited by 159
Metadata
- Authors
- Forouhar, A. S., Liebling, M., Hickerson, A., Nasiraei-Moghaddam, A., Tsai, H.-J., Hove, J. R., Fraser, S. E., Dickinson, M. E., & Gharib, M.
- Venue
- Science
- Published
- 2006-05-05
- Volume
- 312
- Issue
- 5774
- Pages
- 751-753
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1968732273
- Cited by
- 277
- References
- 9
- FWCI
- 8.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Forouhar, A. S., Liebling, M., Hickerson, A., Nasiraei-Moghaddam, A., Tsai, H.-J., Hove, J. R., Fraser, S. E., Dickinson, M. E., & Gharib, M. (2006). The Embryonic Vertebrate Heart Tube Is a Dynamic Suction Pump. Science. https://doi.org/10.1126/science.1123775
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
