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Cited by 248Cerebrospinal fluid and hydrocephalusTraumatic Brain Injury and Neurovascular DisturbancesBarrier Structure and Function Studies

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Glymphatic influx and clearance are accelerated by neurovascular coupling

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Holstein-Rønsbo, Stephanie, Gan, Yiming, Giannetto, Michael J., Rasmussen, Martin Kaag, Sigurdsson, Björn, Beinlich, Felix Ralf Michael, Rose, Laura, Untiet, Verena, Hablitz, Lauren M., Kelley, Douglas H., Nedergaard, Maiken·2023·Nature Neuroscience
DOI 10.1038/s41593-023-01327-2PMC PMC10500159
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Metadata

Authors
Holstein-Rønsbo, S., Gan, Y., Giannetto, M. J., Rasmussen, M. K., Sigurdsson, B., Beinlich, F. R. M., Rose, L., Untiet, V., Hablitz, L. M., Kelley, D. H., & Nedergaard, M.
Affiliations
  • University of Rochester Medicine (US)
  • University of Copenhagen (DK)
Corresponding author
Nedergaard, Maiken
ORCID
Venue
Nature Neuroscience
Publisher
Springer Science and Business Media LLC
Published
2023-06
Volume
26
Issue
6
Pages
1042-1053
ISSN
  • 1097-6256 (ISSN-L)
  • 1546-1726
DOI
10.1038/s41593-023-01327-2
PMC
PMC10500159
OpenAlex
W4378980475
Cited by
248
References
11
Citations by year
2026: 81 · 2025: 84 · 2024: 69 · 2023: 14
FWCI
40.89
Type
journal article
Language
en
Update notices
correction (2023-09-04)
Open access
Licence
Locations
  • Nature Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, other-oa)
  • PubMed Central (acceptedVersion)
Funders
  • Lundbeckfonden (R230-2016-2135, R386-2021-165)
  • Novo Nordisk Fonden (NNF20OC0066419)
  • U.S. Department of Health & Human Services | National Institutes of Health (R01AT012312RF1AG057575, R01AT011439, U19 NS128613)
  • United States Department of Defense | United States Army | U.S. Army Corps of Engineers (MURI W911NF1910280)
  • The Simon and Adelson foundations
Topics
  • Health Sciences › Medicine › Clinical Neurology › Cerebrospinal fluid and hydrocephalus
  • Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
  • Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
Keywords
glymphatic system, neurovascular coupling, functional hyperemia, cerebrospinal fluid flow, waste clearance, vascular smooth muscle cells, arterial pulsatility, somatosensory cortex, whisker stimulation, particle tracking velocimetry, optogenetic manipulation
MeSH terms
Neurovascular Coupling, Glymphatic System, Animals, Brain, Hemodynamics, Hyperemia, Mice

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