Lowering LDL—not only how low, but how long?
Brown, Michael S., Goldstein, Joseph L.·2006·Science
Cited by (204)
Items 101–200 of 204
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- A Softgel Dietary Supplement Containing Esterified Plant Sterols and Stanols Improves the Blood Lipid Profile of Adults with Primary Hypercholesterolemia: A Randomized, Double-Blind, Placebo-Controlled Replication StudyJames M. McKenney, Belinda H. Jenks, Ed Shneyvas, James R. Brooks, Sonia F Shenoy, Chad M. Cook, Kevin Carl Maki · 2013 · Journal of the Academy of Nutrition and Dietetics
- Genetic determinants of plasma lipoproteinsRebecca L. Pollex, Robert Alexander Hegele · 2007 · Nature Clinical Practice Cardiovascular Medicine
- Phytonutrients of Bitter Apricot Seeds Modulate Human Lipid Profile and LDL Subfractions in Adults with Elevated Cholesterol LevelsJana Kopčeková, Anna Kolesárová, Marianna Schwarzová, Anton Kováčik, Jana Mrázová, Martina Gažarová, Petra Lenártová, Peter Chlebo, Adriana Kolesárová · 2022 · International Journal of Environmental Research and Public Health
- PCSK9 in Liver Cancers at the Crossroads between Lipid Metabolism and ImmunityMalak Alannan, Nabil Georges Seidah, Aksam J. Merched · 2022 · Cells
- Low-Density Lipoprotein Cholesterol: How Low Can We Go?Daniel P. Sherbet, Puja Garg, Emmanouil S. Brilakis, Subhash Banerjee · 2013 · American Journal of Cardiovascular Drugs
- Avances en el tratamiento de la hipercolesterolemiaJuan Francisco Ascaso · 2010 · Endocrinología y Nutrición
- Cargo Receptor-Mediated ER Export in Lipoprotein Secretion and Lipid HomeostasisXiao Wang, Xiaowei Chen · 2022 · Cold Spring Harbor Perspectives in Biology
- Phosphoethanolamine-complexed C-reactive protein: A pharmacological-like macromolecule that binds to native low-density lipoprotein in human serumSanjay K. Singh, Madathilparambil V. Suresh, Deborah Prayther, Jonathan P. Moorman, Antonio E. Rusiñol, Alok Chandra Agrawal · 2008 · Clinica Chimica Acta
- The Rationale for Initiating Treatment of Hypercholesterolemia in Young AdulthoodDaniel Howard Steinberg · 2012 · Current Atherosclerosis Reports
- Novel screening system revealed that intracellular cholesterol trafficking can be a good target for colon cancer preventionShingo Miyamoto, Takumi Narita, Masami Komiya, Gen Fujii, Takahiro Hamoya, Ruri Nakanishi, Shuya Tamura, Yurie Kurokawa, Maiko Takahashi, Michihiro Mutoh · 2019 · Scientific Reports
- Evolution and CholesterolStanley Boyd Eaton · 2009 · World review of nutrition and dietetics
- Comparison of LDL-C Reduction Using Different Evolocumab Doses and IntervalsScott M. Wasserman, Marc Steven Sabatine, Michael J. Koren, Robert Patrick Giugliano, Jason C. Legg, Maurice G. Emery, Sameer Doshi, Thomas Liu, Ransi M. Somaratne, John P. Gibbs · 2018 · Journal of Cardiovascular Pharmacology and Therapeutics
- Alirocumab for low-density Lipoprotein Cholesterol LoweringEli M. Roth · 2018 · Future Cardiology
- A New Approach to Primary Prevention of Cardiovascular DiseaseJohn B. Kostis · 2007 · The American Journal of Medicine
- Statins for All?Scott M. Grundy · 2014 · The American Journal of Cardiology
- How Low an LDL-C Should We Go With Statin Therapy?William J. Kostis · 2014 · Current Atherosclerosis Reports
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- Molecular imaging in atherosclerosisAli Bassir, William Raynor, Peter Sang Uk Park, Thomas J. Werner, Abass A. Alavi, Mona-Elisabeth R. Revheim · 2022 · Clinical and Translational Imaging
- Effects of pcsk9 siRNA on THP-1 Derived Macrophages Apoptosis Induced by oxLDL*Lu-Shan Liu, Min XIE, Zhisheng Jiang, Qiong Yang, Li-Hong PAN, Chunyan Wu, Zhi‐Han Tang, Chao‐Ke Tang, Dang-heng Wei, Zuo Wang · 2009 · PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
- Evidence that Low Density Lipoprotein Is the Primary Cause of Atherosclerotic Cardiovascular Disease: A Bradford-Hill ApproachDavid S. Schade, Deborah Helitzer, Philip Eaton · 2017 · World Journal of Cardiovascular Diseases
- Target discovery using biobanks and human geneticsMichael A. Hicks, Claire Hou, Arya Iranmehr, Krisztina Marosi, Ewen F. Kirkness · 2019 · Drug Discovery Today
- The Legacy Effect in Treating HypercholesterolemiaJohn B. Kostis, Mrinali Shetty, Yuvraj Singh Chowdhury, William J. Kostis · 2020 · Journal of Cardiovascular Pharmacology and Therapeutics
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- Guidelines for the Prevention of Symptomatic Cardiovascular Disease, Based upon the Presence of Coronary Artery Calcified Plaque—Provided by the Society for the Prevention of Symptomatic Heart DiseaseDavid S. Schade, S S Obenshain, Martin Hickey, Jennifer Febbo, Samuel Wann, Robert Philip Eaton · 2022 · World Journal of Cardiovascular Diseases
- Targeting LDL aggregation decreases atherosclerotic lipid burden in a humanized mouse model of familial hypercholesterolemia: Crucial role of ApoB100 conformational stabilizationAleyda Benitez‐Amaro, E. Garcia, Maria Teresa La Chica Lhoëst, A. Martínez, Carla Borràs, Mireia Tondo, María Virtudes Céspedes, Pablo Caruana, Antonietta Pepe, Brigida Bochicchio et al. · 2024 · Atherosclerosis
- Atherothrombotic comorbidity in the rheumatic diseases. The evidence becomes clearer. What should clinicians do?Inmaculada del Rincón · 2009 · Arthritis Care & Research
- Aggressive Management of Obesity in Children and Young Adults: The Known Challenges and Potential OpportunitiesPhilip J. Barter, C.L. Shear · 2007 · Clinical Pharmacology & Therapeutics
- Starting early to control all risk factors in order to prevent coronary heart diseaseHenry C. McGill, Clyde Alex McMahan · 2010 · Clinical Lipidology
- Buffering of gene dosage response curves for human complex traitsNikhil Milind, Courtney J. Smith, Huisheng Zhu, Tamara Gjorgjieva, Jeffrey P. Spence, Jonathan K. Pritchard · 2026 · Cell Genomics
- Age‐Neutral Guidelines for the Primary Prevention of Cardiovascular DiseaseWilliam J. Kostis, John B. Kostis · 2009 · Journal of Clinical Hypertension
- Atherosclerosis: Is a cure in sight?Don P. Wilson, Samuel S. Gidding · 2015 · Journal of clinical lipidology
- Treating Hypercholesterolemia and Hypertension Based on Lifetime Global RiskJohn B. Kostis · 2007 · The American Journal of Cardiology
- Regulation Of Hepatic Production Of Lipoproteins Containing Apolipoprotein B By ER-Associated DegradationLouis R. Lapierre, Roger S. McLeod · 2007 · Future Lipidology
- Treatment Targets in the Management of Dyslipidemias: Which Targets in Whom?Scott M. Grundy · 2012 · Current Cardiology Reports
- Genética de la hipercolesterolemia familiarStoll, Mario, Dell’Oca, Nicolás · 2019 · Revista Uruguaya de Cardiología
- Hypocholesterolemic effects of plant sterols and stanols: Do the dose–response curves diverge?Kevin Carl Maki, Tia M. Rains · 2011 · Prostaglandins Leukotrienes and Essential Fatty Acids
- Statins and primary prevention: Is all the evidence in?Shirya Rashid, Gordon A. Francis · 2008 · Canadian Journal of Cardiology
- Molecular genetics for familial hypercholesterolemiaNicola Marziliano, Alessandro Medoro, Stefano Folzani, Mariano Intrieri, Claudio Reverberi · 2022 · Reviews in Cardiovascular Medicine
- Clinical trials reportMichael B. Clearfield · 2007 · Current Atherosclerosis Reports
- Long-Term Exposure to High Low-Density Lipoprotein Cholesterol Levels and Clinical Course in Secondary Prevention After Coronary Artery DiseaseIchiro Matsumoto, Kagari Mukaida, Kensaku Wada, Mizuki Kurozumi, Tsunetatsu Namba, Yuichiro Takagi · 2025 · Circulation Reports
- Association between the rs615563 variant of PCSK9 gene and circulating lipids and Type 2 diabetesSamira Taghizadeh Jazdani, Hajieh Bibi Shahbazian, Bahman Cheraghian, Mohammad Taha Jalali, Narges Mohammadtaghvaei · 2021 · BMC Research Notes
- Atherosclerosis, Vulnerable Plaques, and Acute Coronary SyndromesJacob Fog Bentzon, Erling Falk · 2012 · Elsevier eBooks
- What do high blood resistin levels mean for patients on statin therapy?Shirya Rashid · 2013 · Expert Review of Cardiovascular Therapy
- Low-dose eicosapentaenoic acid and/or docosahexaenoic acid and triglyceride loweringKevin Carl Maki, Tia M. Rains · 2010 · Nutrition Reviews
- Ten reasons to treat all individuals with a positive coronary artery calcium scoreDavid S. Schade, Allen Adolphe, James C. Blankenship, R. Philip Eaton · 2026 · The American Journal of Medicine
- Lipid Nephrotoxicity: New Concept for an Old DiseaseXiong Zhong Ruan, Zac Varghese, J F Moorhead · 2014 · Springer eBooks
- Statin Therapy in Hyperlipidemia: Balancing the Risk and BenefitsKenneth R. Feingold · 2014 · The Endocrine Society eBooks
- Genetic and polygenic contributions to familial hypercholesterolemia in Thailand: Implications for diagnosis and lipid managementPhongthana Pasookhush, Apinya Surawit, Sophida Suta, Sureeporn Pumeiam, Pichanun Mongkolsucharitkul, Bonggochpass Pinsawas, Suphawan Ophakas, Korapat Mayurasakorn · 2025 · Journal of clinical lipidology
- Genetic Risk Score Enables a Vaccine for Early Primary Prevention of CADRobert Roberts · 2025 · Methodist DeBakey Cardiovascular Journal
- Biometric, nutritional, biochemical, and cardiovascular outcomes in male rats submitted to an experimental model of early weaning that mimics mother abandoningRogério Barbosa de Magalhães Barros, Thaís Alvim-Silva, Júlia Raquel Nunes de Souza, Emiliana Barbosa Marques, Nazareth N. Rocha, Fernanda Brito, Christianne Brêtas Vieira Scaramello · 2020 · Journal of Developmental Origins of Health and Disease
- Proprotein Convertase PCSK9Nabil Georges Seidah · 2012 · Handbook of Proteolytic Enzymes
- Studies on PCSK9 in the regulation of cholesterol metabolismLena Persson · 2011 · Figshare
- Therapeutic potential of phosphoethanolamine-bound C-reactive protein in atherosclerosisAlok Chandra Agrawal · 2008 · Future Lipidology
- LDL cholesterol: should guidelines include targets?Subhash Banerjee, Dhiman Kahali, Avantika Banerjee, Emmanouil S. Brilakis · 2014 · Expert Review of Cardiovascular Therapy
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- Therapeutic Lifestyle Change for the Prevention and Treatment of Hyperlipidemia and Coronary Artery DiseaseRajesh Gupta, Bashar Almadani, Neil J. Stone · 2011 · Humana Press eBooks
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- The E3 ubiquitin ligase c-IAP1 regulates PCSK9-mediated LDLR degradation: Linking the TNF-&x03B1; pathway to cholesterol uptakeWeiming Xu, Lizhi Liu · 2010 · Nature Precedings
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- The Effect of Oat and Barley beta-glucan on LDL-C and Emerging Clinical Lipid Targets for Cardiovascular DiseaseHoang Vi Thanh Ho · 2015 · TSpace (University of Toronto)
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