The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
TOPLESS Mediates Auxin-Dependent Transcriptional Repression During Arabidopsis Embryogenesis
Abstract
The transcriptional response to auxin is critical for root and vascular development during Arabidopsis embryogenesis. Auxin induces the degradation of AUXIN/INDOLE-3-ACETIC ACID (AUX/IAA) transcriptional repressors, freeing their binding partners, the AUXIN RESPONSE FACTOR (ARF) proteins, which can activate transcription of auxin response genes. We show that TOPLESS (TPL) can physically interact with IAA12/BODENLOS (IAA12/BDL) through an ETHYLENE RESPONSE FACTOR (ERF)–associated amphiphilic repression (EAR) motif. TPL can repress transcription in vivo and is required for IAA12/BDL repressive activity. In addition, tpl-1 can suppress the patterning defects of the bdl-1 mutant. Direct interaction between TPL and ARF5/MONOPTEROS, which is regulated by IAA12/BDL, results in a loss-of-function arf5 / mp phenotype. These observations show that TPL is a transcriptional co-repressor and further our understanding of how auxin regulates transcription during plant development.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The F-box protein TIR1 is an auxin receptor
Dharmasiri, N., Dharmasiri, S., & Estelle, M. (2005) · Nature · doi:10.1038/nature03543 · Cited by 2,083
Cited by
Recent advances and emerging trends in plant hormone signalling
Santner, A., & Estelle, M. (2009) · Nature · doi:10.1038/nature08122 · Cited by 960
DWARF 53 acts as a repressor of strigolactone signalling in rice
Jiang, L., Liu, X., Xiong, G., Liu, H., Chen, F., Wang, L., Meng, X., Liu, G., Yu, H., Yuan, Y., et al. (2013) · Nature · doi:10.1038/nature12870 · Cited by 868
Leyser, O. (2018) · Plant Physiology · doi:10.1104/pp.17.00765 · Cited by 715
Auxin Receptors and Plant Development: A New Signaling Paradigm
Mockaitis, K., & Estelle, M. (2008) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.23.090506.123214 · Cited by 651
The auxin signalling network translates dynamic input into robust patterning at the shoot apex
Vernoux, T., Brunoud, G., Farcot, E., Morin, V., Van den Daele, H., Legrand, J., Oliva, M., Das, P., Larrieu, A., Wells, D., et al. (2011) · Molecular Systems Biology · doi:10.1038/msb.2011.39 · Cited by 576
Metadata
- Authors
- Szemenyei, H., Hannon, M., & Long, J. A.
- Venue
- Science
- Published
- 2008-03-07
- Volume
- 319
- Issue
- 5868
- Pages
- 1384-1386
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2008807830
- Cited by
- 801
- References
- 1
- FWCI
- 41.65
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: TOPLESS Mediates Auxin-Dependent Transcriptional Repression During Arabidopsis Embryogenesis. https://app.cochat.ai/papers/10.1126/science.1151461
- The paper
- Szemenyei, H., Hannon, M., & Long, J. A. (2008). TOPLESS Mediates Auxin-Dependent Transcriptional Repression During Arabidopsis Embryogenesis. Science. https://doi.org/10.1126/science.1151461
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
