Lhx2 Selector Activity Specifies Cortical Identity and Suppresses Hippocampal Organizer Fate
Mangale, Vishakha S., Hirokawa, Karla E., Satyaki, Prasad R. V., Gokulchandran, Nandini, Chikbire, Satyadeep, Subramanian, Lakshmi, Shetty, Ashwin S., Martynoga, Ben, Paul, Jolly, Mai, Mark V., Li, Yuqing, Flanagan, Lisa A., Tole, Shubha, Monuki, Edwin S.·2008·Science
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Items 201–300 of 315
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- FoxG1 Directly Represses Dentate Granule Cell Fate During Forebrain DevelopmentXiao Han, Xiaochun Gu, Qianqian Zhang, Qingxia Wang, Yao Cheng, Samuel J. Pleasure, Chunjie Zhao · 2018 · Frontiers in Cellular Neuroscience
- Specification of Cortical Projection NeuronsJessica L. MacDonald, Ryann M. Fame, Eiman Azim, Sara J. Shnider, Bradley J. Molyneaux, Paola Arlotta, Jeffrey D. Macklis · 2013 · Elsevier eBooks
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- Transcription factors in microcephalyYoungshin Lim · 2023 · Frontiers in Neuroscience
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- Roof plate mediated morphogenesis of the forebrain: New players join the gameSandeep Kumar Gupta, Jonaki Sen · 2016 · Developmental Biology
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- Neural Induction and Pattern FormationAndrew Lumsden, Clemens Martin Kiecker · 2013 · Elsevier eBooks
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- Lmx1a is a master regulator of the cortical hemIgor Y. Iskusnykh, Nikolai S. Fattakhov, Yiran Li, Laure Bihannic, Matthew K. Kirchner, Ekaterina Y. Steshina, Paul A. Northcott, Victor V. Chizhikov · 2023 · eLife
- Molecular bases of cortico-cerebral regionalizationAntonello Mallamaci · 2011 · Progress in brain research
- LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx2Yusaku Kodaka, Kiyoko Tanaka, Kenji Kitajima, Kosuke Tanegashima, Ryoichi Matsuda, Takahiko Hara · 2014 · Experimental Cell Research
- Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral CortexYoko Arai, Andrzej W. Cwetsch, Eva Coppola, Sara Cipriani, Hidenori Nishihara, Hiroaki Kanki, Yoann Saillour, Betty Freret-Hodara, Annie Dutriaux, Norihiro Okada et al. · 2019 · Cell Reports
- Human pluripotent stem cell-derived models of the hippocampusHaruka Nishimura, Yun Li · 2024 · The International Journal of Biochemistry & Cell Biology
- PRDM16 co-operates with LHX2 to shape the human brainVarun Suresh, Bidisha Bhattacharya, Rami Yair Tshuva, Miri Danan-Gotthold, Tsviya Olender, Mahima Bose, Saurabh J. Pradhan, Bruria Ben Zeev, Richard S. Smith, Shubha Tole et al. · 2024 · Oxford Open Neuroscience
- Seizure evoked regulation of LIM-HD genes and co-factors in the postnatal and adult hippocampusVanisha Lakhina, Lakshmi Subramanian, Dhananjay Huilgol, Ashwin S. Shetty, Vidita A. Vaidya, Shubha Tole · 2013 · F1000Research
- Analysis of the Expression Pattern of Cajal-Retzius Cell Markers in the Xenopus laevis ForebrainSara Jiménez, Nerea Moreno · 2021 · Brain Behavior and Evolution
- Transcription of follicle-stimulating hormone subunit genes is modulated by porcine LIM homeobox transcription factors, LHX2 and LHX3Saishu Yoshida, Takako Katō, Naoto Nishimura, Naoko Kanno, Mo Chen, Hiroki Ueharu, Hiroto Nishihara, Yukio Kato · 2016 · Journal of Reproduction and Development
- A model of neocortical area patterning in the lissencephalic mouse may hold for larger gyrencephalic brainsWilliam David Jones, Sarah M. Guadiana, Elizabeth Ann Grove · 2019 · The Journal of Comparative Neurology
- The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genesXiong Wen Yang, Rong Wan, Zhiwen Liu, Su Feng, Jiaxin Yang, Naihe Jing, Ke Tang · 2023 · eLife
- The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrainKevin Kofi Adutwum-Ofosu, Dario Magnani, Thomas Theil, David Jonathan Price, Vassiliki Fotaki · 2015 · Brain Structure and Function
- Forced Expression of Foxg1 in the Cortical Hem Leads to the Transformation of Cajal-Retzius Cells into Dentate Granule NeuronsBin Liu, Hongmei Xiao, Chunjie Zhao · 2018 · Journal of Developmental Biology
- Specification of cortical projection neuronsAbdulkadir Özkan, Jessica L. MacDonald, Ryann M. Fame, Yasuhiro Itoh, Manuel Peter, Omer Durak, Jeffrey D. Macklis · 2020 · Elsevier eBooks
- LHX2 in germ cells control tubular organization in the developing mouse testisNeha Singh, Domdatt Singh, Anshul Bhide, Richa Sharma, Shilpa Bhowmick, Vainav V. Patel, Deepak N. Modi · 2023 · Experimental Cell Research
- Regulation of chromatin accessibility and gene expression in the developing hippocampal primordium by LIM-HD transcription factor LHX2Varun Suresh, Bhavana Muralidharan, Saurabh J. Pradhan, Mahima Bose, Leora D’Souza, Arpan Parichha, Puli Chandramouli Reddy, Sanjeev Galande, Shubha Tole · 2023 · PLoS Genetics
- From Embryonic to Adult Neurogenesis in the Dentate GyrusTatsunori Seki · 2011 · Springer eBooks
- Chip Is Required for Posteclosion Behavior inDrosophilaHari K. Padmanabhan, Mugdha Deshpande, Neha Sharma, Neha Rajadhyaksha, Nitya Ramkumar, Ken‐ichi Kimura, Verônica Rodrigues, Shubha Tole · 2008 · Journal of Neuroscience
- TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoidsMomoko Watanabe, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie E. Buth, Wen Gu, Amanda J. Collier, Osvaldo A. Miranda, Di Chen, Shan Sabri et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Mouse cortical cellular diversification through lineage progression of radial gliaLin Yang, Zi‐Wu Wang, Yanjing Gao, Zhenmeiyu Li, Guoping Liu, Zhejun Xu, Zhuangzhi Zhang, Yan You, Zhengang Yang, Xiaosu Li · 2025 · Genes & Development
- Temporal Differences in Interneuron Invasion of Neocortex and Piriform Cortex during Mouse Cortical DevelopmentHsiang-Wei Hsing, Zi-Hui Zhuang, Zhen‐Xian Niou, Shen‐Ju Chou · 2019 · Cerebral Cortex
- LIM Homeobox Domain 2 Is Required for Corneal Epithelial HomeostasisRachel Sartaj, Ru-ik Chee, Jing Yi Yang, Pengxia Wan, Aihong Liu, Victor H. Guaiquil, Elaine V. Fuchs, Mark I. Rosenblatt · 2015 · Stem Cells
- Telencephalon patterningShubha Tole, Jean M. Hébert · 2020 · Elsevier eBooks
- Morphogens, patterning centers, and their mechanisms of actionElizabeth Ann Grove, Edwin S. Monuki · 2020 · Elsevier eBooks
- The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genesXiong Wen Yang, Rong Wan, Zhiwen Liu, Su Feng, Jiaxin Yang, Naihe Jing, Ke Tang · 2023 · eLife
- Developmental Expression Pattern of Hspb8 mRNA in the Mouse Brain: Analysis Through Online DatabasesNoelia García‐Lax, Laura Tomás‐Roca, Faustino Marı́n · 2011 · The Anatomical Record
- Deciphering the Retinal Epigenome during Development, Disease and Reprogramming: Advancements, Challenges and PerspectivesCristina Zibetti · 2022 · Cells
- Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineagesFrédéric Causeret, Maxime Fayon, Matthieu X. Moreau, Enrico Ne, Roberto Oleari, Carlos M. Parras, Anna Maria Cariboni, Alessandra Pierani · 2023 · The Journal of Comparative Neurology
- Telencephalon PatterningShubha Tole, Jean M. Hébert · 2013 · Elsevier eBooks
- Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial gliaArpan Parichha, Debarpita Datta, Varun Suresh, Mallika Chatterjee, Michael J. Holtzman, Shubha Tole · 2022 · Development
- Development of subdomains in the medial pallium of Xenopus laevis and Trachemys scripta: Insights into the anamniote-amniote transitionSara Jiménez, Nerea Moreno · 2022 · Frontiers in Neuroanatomy
- PAX6 can substitute for LHX2 and override NFIA-induced astrogliogenesis in developing hippocampus in vivoVeena Kinare, Ashwin S. Shetty, Agasthya Suresh, Shubha Tole · 2018 · Journal of Biosciences
- BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrainHuong Nguyen, Godwin Sokpor, Arpan Parichha, Linh Pham, Nidhi S. Saikhedkar, Yuanbin Xie, Pauline Antonie Ulmke, Joachim Rosenbusch, Mehdi Pirouz, Rüdiger Behr et al. · 2022 · Frontiers in Cell and Developmental Biology
- The transcription factor LHX2 suppresses astrocyte proliferation in the postnatal mammalian cerebral cortexArchana Iyer, Reanne Fronteiro, Prachi Bhatia, Sanjna Kumari, Amrita Singh, Jiafeng Zhou, Riccardo Bocchi, Rishikesh Narayanan, Shubha Tole · 2025 · Development
- Self-organization and applications of neural organoidsHideya Sakaguchi · 2025 · European Journal of Cell Biology
- Influence of bone morphogenetic protein type IA receptor conditional knockout in lens on expression of bone morphogenetic protein 4 in lens.Qi Zhao, Jiangyue Zhao, Jinsong Zhang · 2015 · Europe PMC (PubMed Central)
- Broad Integration of Expression Maps and Co-Expression Networks Compassing Novel Gene Functions in the BrainYuko Okamura-Oho, Kazuro Shimokawa, Masaomi Nishimura, Satoko Takemoto, Akira Sato, Teiichi Furuichi, Hideo Yokota · 2014 · Scientific Reports
- Area patterning of the mammalian neocortexElizabeth Ann Grove · 2020 · Elsevier eBooks
- Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in uteroMohammed Abderrafi Benotmane, Klaus Rudiger Trott · 2023 · International Journal of Radiation Biology
- Specific contribution of neurons from the Dbx1 lineage to the piriform cortexThando W. Shabangu, Hung-Lun Chen, Zi-Hui Zhuang, Alessandra Pierani, Chien‐Fu F. Chen, Shen‐Ju Chou · 2021 · Scientific Reports
- Only scratching the cell surface: extracellular signals in cerebrum developmentJean M. Hébert · 2013 · Current Opinion in Genetics & Development
- Selecting cells to make cerebral cortexYijing Chen, David Jonathan Price · 2008 · Journal of Biosciences
- Ldb1 mediates trans enhancement in mammalsK. Monahan, A. Horta, A.M. Mumbay-Wafula, Lei Li, Yingdong Zhao, Paul E. Love, Stavros Lomvardas · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like behavior (BTBR) or its absence (С57BL/6J)П. Д. Правикова, Mhd Amin Arssan, E. A. Zalivina, Elena M. Kondaurova, Elizabeth A. Kulikova, Irina I. Belokopytova, Vladimir S. Naumenko · 2024 · Vavilov Journal of Genetics and Breeding
- Genes expressed in mouse cortical progenitors are enriched in Pax, Lhx, and Sox transcription factor putative binding sitesAmandine Béry, Yohann Mérot, Sylvie Rétaux · 2015 · Brain Research
- Overlapping Interstitial Deletions of the Region 9q22.33 to 9q33.3 of Three Patients Allow Pinpointing Candidate Genes for Epilepsy and Cleft Lip and PalateRenáta Szalai, Ágnes Till, András Szabó, Béla Melegh, Kinga Hadzsiev, Márta Czakó · 2022 · Molecular Syndromology
- Migration in the HippocampusG. Li, Samuel J. Pleasure · 2013 · Elsevier eBooks
- Lhx2 regulates temporal changes in chromatin accessibility and transcription factor binding in retinal progenitor cellsCristina Zibetti, Sheng Liu, Jun Wan, Jiang X. Qian, Seth Blackshaw · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Analysis of downstream targets of PAX6 and LHX2, fundamental regulators of the developing mammalian neocortexMansi Srivastava, Varun Suresh, Shubha Tole · 2024 · Journal of Biosciences
- Novel Insights into Emx2 and Dmrta2 Cooperation during Cortex Development and Evidence for Dmrta2 Function in the Choroid PlexusJithu Anirudhan, Xueyi Shen, Tünde Szemes, Marc Dieu, Abdulkader Azouz, Louise Conrard, Nicolas Passon, Gilles Doumont, Maren Sitte, Younès Achouri et al. · 2025 · Journal of Neuroscience
- Bidirectional interaction between protocadherin 8 and the transcription factor Dbx1 regulates cerebral cortex developmentAndrzej W Cwetsch, Sofia Ferreira, Elodie Delberghe, Javier Gilabert‐Juan, Matthieu X. Moreau, Yoann Saillour, Pau García-Bolufer, Saray Calvo-Parra, José González‐Martínez, Durcia Massoukou et al. · 2026 · Development
- Analysis of Potential Genomic Confounding in Genetic Association Studies and an Online Genomic Confounding Browser (GCB)Christopher A. Raistrick, Khalid Khalaf Alharbi, Ian N.M. Day, Tom R. Gaunt · 2011 · Annals of Human Genetics
- Distinct roles of homeoproteins in brain topographic mapping and in neural circuit formationOlivier Stettler, Kenneth L. Moya · 2014 · Seminars in Cell and Developmental Biology
- Mammalian Cortical Regional SpecificationAthéna Rebecca Ypsilanti, John L.R. Rubenstein · 2023 · Wiley eBooks
- Instructions for the hippocampusMonica Hoyos Flight · 2008 · Nature reviews. Neuroscience
- Cortical hem signaling center: functions, development, and potential implications for evolution and brain disordersVictor V. Chizhikov, Igor Y. Iskusnykh · 2024 · Neural Regeneration Research
- Modification of Lhx2 activity for ex vivo amplification of human iPSC-derived hematopoietic stem/progenitor cellsKenji Kitajima, Yuna Takahashi, Hikaru Ando, Minako Shingai, Mako Hamasaki, Miyu Tanikawa, Mai Kanokoda, Marino Nakajima, Yasumasa Nishito, Takahiko Hara · 2024 · Frontiers in Cell and Developmental Biology
- Cajal-Retzius fate specification is disrupted by constitutive activation of β-Catenin in hem progenitorsAmrita Singh, Arpan Parichha, Debarpita Datta, Mallika Chatterjee, Shubha Tole · 2026 · Development
- Ritka genomikai betegségek azonosítása array komparatív genomhibridizációs módszerrel – elsőként MagyarországonBalázs Duga, Márta Czakó, Kinga Hadzsiev, Katalin Komlósi, Katalin Sümegi, Péter Kisfali, György Kosztolányi, Béla Melegh · 2014 · Orvosi Hetilap
- Forebrain roof plate morphogenesis and hippocampus development in the chick embryoSandeep Kumar Gupta, Niveda Udaykumar, Jonaki Sen · 2020 · The International Journal of Developmental Biology
- Early Neuronal Differentiation/patterning of the Human Pallium, Modeling by in Vitro Systems, and Disruption in Developmental DisordersSoraya Scuderi, Alexandre Jourdon, Flora Maria Vaccarino · 2023 · Wiley eBooks
- LHX2 regulates dendritic morphogenesis in layer II/III of the neocortex via distinct pathways in progenitors and postmitotic neuronsMahima Bose, Sreenath Ravindran, Sanjna Kumari, Achintya Srivastava, Archana Iyer, Binita Vedak, Ishita Talwar, Rishikesh Narayanan, Shubha Tole · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Profiles of Women in Science: Shubha Tole, Distinguished Professor at the Tata Institute of Fundamental Research in Mumbai, India, and President of the International Brain Research OrganizationMarian Joëls · 2026 · European Journal of Neuroscience
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- Building the Body, Building the BrainMallika Chatterjee, Dhananjay Huilgol, Shubha Tole · 2012 · Journal of the Indian Institute of Science
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- Variation of human neural stem cells generating organizer states in vitro before committing to cortical excitatory or inhibitory neuronal fatesNicola Micali, Suel–Kee Kim, Marcelo Diaz-Bustamante, Genevieve Stein-O’Brien, Seungmae Seo, Joo Heon Shin, Brian G. Rash, Shaojie Ma, Yanhong Wang, Nicolas A. Olivares et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Cortical patterning and neuronal migration are under the guide of BAF complex functionalityGodwin Sokpor · 2020 · eDiss (Georg-August-Universität Göttingen)
- SynthesisGeorg F. Striedter, R. Glenn Northcutt · 2019 · Oxford University Press eBooks
- Faculty Opinions recommendation of Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects.Rolf W. Stottmann · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Gene behind your thoughtsBiplab Das · 2008 · Nature India
- Faculty Opinions recommendation of LHX2- and LDB1-mediated trans interactions regulate olfactory receptor choice.Charles A. Greer · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Generation of Neurons and Their Integration in Pre-Existing Circuits in the Postnatal Brain: Signalling in Physiological and Regenerative ContextsMira, Helena, Díez del Corral, Ruth, Morales, Aixa V. · 2020 · Frontiers research topics
- Faculty Opinions recommendation of Comprehensive functional genomic resource and integrative model for the human brain.John I. Nürnberger · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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- Migration in the hippocampusHirofumi Noguchi, Guangnan Li, Samuel J. Pleasure · 2020 · Elsevier eBooks
- The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genesXiong Wen Yang, Rong Wan, Zhiwen Liu, Su Feng, Jiaxin Yang, Naihe Jing, Ke Tang · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genesXiong Wen Yang, Rong Wan, Zhiwen Liu, Su Feng, Jiaxin Yang, Naihe Jing, Ke Tang · 2023 · eLife
- Reviewer #2 (Public Review): The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes2023 · eLife
- Reviewer #1 (Public Review): The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes2023 · eLife
- Reviewer #3 (Public Review): The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes2023 · eLife
- eLife Assessment: The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genesJoseph G. Gleeson · 2023 · eLife
- The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genesXiong Wen Yang, Rong Wan, Zhiwen Liu, Su Feng, Jiaxin Yang, Naihe Jing, Ke Tang · 2023 · eLife