TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

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1. Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons
   Sato, T., Takeuchi, S., Saito, A., Ding, W., Bamba, H., Matsuura, H., Hisa, Y., Tooyama, I., Urushitani, M. · 2009 · Neuroscience
2. IN VITRO AND IN VIVO MODELS OF AMYOTROPHIC LATERAL SCLEROSIS: AN UPDATED OVERVIEW
   Auderlan Mendonça de Gois, Deise Maria Furtado de Mendonça, Marco Aurélio M. Freire, José Ronaldo dos Santos · 2020 · Brain Research Bulletin
3. TDP-43-stratified single-cell proteomics of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis
   Amanda J. Guise, Santosh A. Misal, Richard H. Carson, Jen-Hwa Chu, Hannah Boekweg, Daisha Van Der Watt, Nora C. Welsh, Thy Truong, Yiran Liang, Shanqin Xu et al. · 2024 · Cell Reports
4. Physiological protein aggregation run amuck: stress granules and the genesis of neurodegenerative disease.
   Benjamin L. Wolozin · 2014 · PubMed
5. Pathogenic TARDBP Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: Disease-Associated Pathways
   Sami J. Barmada, Steven M. Finkbeiner · 2010 · Reviews in the Neurosciences
6. TARDBP mutations in Parkinson's disease
   Sruti Rayaprolu, Shinsuke Fujioka, Sharleen M. Traynor, Alexandra I. Soto‐Ortolaza, Leonard Petrucelli, Dennis W. Dickson, Rosa Rademakers, Khrista Boylan, Neill R. Graff‐Radford, Ryan J. Uitti et al. · 2012 · Parkinsonism & Related Disorders
7. RNA metabolism in ALS: When normal processes become pathological
   Cristian A. Droppelmann, Danae Campos‐Melo, Muhammad Ishtiaq, Kathryn Volkening, Michael Joseph Strong · 2014 · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
8. Identification of C9orf72 repeat expansions in patients with amyotrophic lateral sclerosis and frontotemporal dementia in mainland China
   Bin Jiao, Beisha Tang, Xiaoyan Liu, Xinxiang Yan, Lin Zhou, Yi Yang, Junling Wang, Kun Xia, Lu Hua Shen · 2013 · Neurobiology of Aging
9. Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases
   Asako Otomo, Lei Pan, Shinji Hadano · 2012 · Neurology Research International
10. Motor neurone disease: a practical update on diagnosis and management
    Pamela J. Shaw, Clare A. Wood-Allum · 2010 · Clinical Medicine
11. Potential Effect of S-Nitrosylated Protein Disulfide Isomerase on Mutant SOD1 Aggregation and Neuronal Cell Death in Amyotrophic Lateral Sclerosis
    Gye Sun Jeon, Tomohiro Nakamura, Jeong-Seon Lee, Won-Jun Choi, Suk‐Won Ahn, Kwang‐Woo Lee, Jung‐Joon Sung, Stuart A. Lipton · 2013 · Molecular Neurobiology
12. SQSTM1 mutations in Han Chinese populations with sporadic amyotrophic lateral sclerosis
    Yongping Chen, Zhenzhen Zheng, Xueping Chen, Rui Huang, Yuan Yang, Lixing Yuan, Lei Pan, Shinji Hadano, Huifang Shang · 2013 · Neurobiology of Aging
13. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients
    Craig L. Bennett, Somasish Ghosh Dastidar, Shuo‐Chien Ling, Bilal Malik, Travis D. Ashe, Mandheer Wadhwa, Derek B. Miller, Chang‐Woo Lee, Matthew B. Mitchell, Michael A. van Es et al. · 2018 · Acta Neuropathologica
14. Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice
    Sander Beel, Sarah Herdewyn, Raheem Fazal, Mathias De Decker, Matthieu Moisse, Wim Robberecht, Ludo Van Den Bosch, Philip Van Damme · 2018 · Molecular Neurodegeneration
15. Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia
    Ramya Ranganathan, Shaila Haque, Kayesha Coley, Stephanie R. Shepheard, Johnathan Cooper‐Knock, Janine Kirby · 2020 · Frontiers in Neuroscience
16. RNA-binding proteins in ALS and FTD: from pathogenic mechanisms to therapeutic insights
    JL Rummens, Sandrine Da Cruz · 2025 · Molecular Neurodegeneration
17. Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice
    Suh Young Jeong, Daniel R. Crooks, Hayden Ollivierre, Manik Chandra Ghosh, Rachid Sougrat, Jaekwon Lee, Sharon S. Cooperman, James B. Mitchell, Carole Beaumont, Tracey Ann Rouault · 2011 · PLoS ONE
18. Motor neuron disease-frontotemporal dementia: a clinical continuum
    Emma M. Devenney, Steve Vucic, John R. Hodges, Matthew C. Kiernan · 2015 · Expert Review of Neurotherapeutics
19. TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1
    Fang He, Amy Krans, Brian D. Freibaum, J. Paul Taylor, Peter K. Todd · 2014 · Human Molecular Genetics
20. Nuclear trafficking in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
    Sonja Prpar Mihevc, Simona Darovic, Anja Kovanda, Ana Bajc Česnik, Vera Župunski, Boris Rogelj · 2016 · Brain
21. Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: Frequency of abnormality and effect on survival
    Zhouwei Xu, Ashwag R. Alruwaili, Robert D. Henderson, Pamela McCombe · 2017 · Journal of the Neurological Sciences
22. Failure to Deliver and Translate—New Insights into RNA Dysregulation in ALS
    Alyssa N. Coyne, Benjamin L. Zaepfel, Daniela C. Zarnescu · 2017 · Frontiers in Cellular Neuroscience
23. ALS and FTD: Where RNA metabolism meets protein quality control
    Jessica Mandrioli, Laura Mediani, Simon Alberti, Serena Carra · 2019 · Seminars in Cell and Developmental Biology
24. Increased expression of TDP-43 in the skin of amyotrophic lateral sclerosis
    Makoto Suzuki, Hirotsugu Mikami, Takeshi Watanabe, Takahiko Yamano, Taisuke Yamazaki, Makoto Nomura, Kazuaki Yasui, Hiroshi Ishikawa, S. Ono · 2010 · Acta Neurologica Scandinavica
25. Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP ‐43‐positive inclusions
    Hiroyuki Honda, Hideomi Hamasaki, Tomihiro Wakamiya, Sachiko Koyama, Satoshi O. Suzuki, Naoki Fujii, Toru Iwaki · 2014 · Neuropathology
26. A hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic ALS in Taiwan
    Ching-Paio Tsai, Bing‐Wen Soong, Pang‐Hsien Tu, Kon‐Ping Lin, Jong‐Ling Fuh, Pei‐Chien Tsai, Yi‐Chun Lu, I‐Hui Lee, Yi‐Chung Lee · 2012 · Neurobiology of Aging
27. The ALS/FTLD‐related RNA‐binding proteins TDP‐43 and FUS have common downstream RNA targets in cortical neurons
    Daiyu Honda, Shinsuke Ishigaki, Yohei Iguchi, Yusuke Fujioka, Tsuyoshi Udagawa, Akio Masuda, Kinji Ohno, Masahisa Katsuno, Gen Sobue · 2013 · FEBS Open Bio
28. Vitamin D as a Potential Therapy in Amyotrophic Lateral Sclerosis
    Alexandro Gianforcaro, Mazen Jamal Hamadeh · 2014 · CNS Neuroscience & Therapeutics
29. ALS/FTD phenotype in two Sardinian families carrying bothC9ORF72andTARDBPmutations
    Adriano Chiò, Gabriella Restagno, Maura Brunetti, Irene Ossola, Andrea Calvo, Antonio Canosa, Cristina Moglia, Gianluca Floris, Paolo Tacconi, Francesco Marrosu et al. · 2012 · Journal of Neurology Neurosurgery & Psychiatry
30. Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease
    Soumitra Ghosh, Robert L. Geahlen · 2015 · EBioMedicine
31. Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Continuum
    Hamideh Shahheydari, Audrey Ragagnin, Adam K. Walker, Reka P. Toth, Marta Vidal, Cyril Jones Jagaraj, Emma R. Perri, Anna Konopka, Jessica M. Sultana, Julie D. Atkin · 2017 · Frontiers in Molecular Neuroscience
32. Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP type C pathology
    Valentina Borghesani, Giovanni Battistella, Maria Luisa Mandelli, Ariane E. Welch, Elizabeth Weis, Kyan Younes, John M Neuhaus, Lea T. Grinberg, WW Seeley, Salvatore Spina et al. · 2020 · NeuroImage Clinical
33. Genetics of Familial Amyotrophic Lateral Sclerosis
    Feneberg Emily, J. Joanna, Johnathan Cooper‐Knock, J. Pamela, Janine Kirby · 2012 · InTech eBooks
34. Phase separation and pathologic transitions of RNP condensates in neurons: implications for amyotrophic lateral sclerosis, frontotemporal dementia and other neurodegenerative disorders
    Aditi Naskar, Asima Nayak, Muthu Raj Salaikumaran, Sonali S. Vishal, Pallavi P. Gopal · 2023 · Frontiers in Molecular Neuroscience
35. Microglia and Astrocytes in Amyotrophic Lateral Sclerosis: Disease-Associated States, Pathological Roles, and Therapeutic Potential
    Justin You, Mohieldin Youssef, Jhune Rizsan Santos, Jooyun Lee, Jeehye Park · 2023 · Biology
36. Reversible Behavioral Phenotypes in a Conditional Mouse Model of TDP-43 Proteinopathies
    Julio A. Alfieri, Natalia S. Pino, Lionel Muller Igaz · 2014 · Journal of Neuroscience
37. The role of SIGMAR1 gene mutation and mitochondrial dysfunction in amyotrophic lateral sclerosis
    Kohji Fukunaga, Yasuharu Shinoda, Hideaki Tagashira · 2014 · Journal of Pharmacological Sciences
38. Invited Article: The Alzheimer disease–frontotemporal lobar degeneration spectrum
    Julie van der Zee, Kristel Sleegers, Christine Van Broeckhoven · 2008 · Neurology
39. TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT
    Helen Ling, Eleanna Kara, Rina Bandopadhyay, John Hardy, Janice L. Holton, Georgia Xiromerisiou, Andrew John Lees, Henry Houlden, Tamás Révész · 2013 · Neurobiology of Aging
40. High frequency of the TARDBP p.Ala382Thr mutation in Sardinian patients with amyotrophic lateral sclerosis
    Sandro Orrù, Emmanouil Manolakos, Nicola Orrù, Haris Kokotas, V. Mascia, Carlo Carcassi, MB Petersen · 2011 · Clinical Genetics
41. Expansive Gene Transfer in the Rat CNS Rapidly Produces Amyotrophic Lateral Sclerosis Relevant Sequelae When TDP-43 is Overexpressed
    David B. Wang, Robert D. Dayton, Phillip P Henning, Cooper D. Cain, Li Ru Zhao, Lisa M. Schrott, Elysse A. Orchard, David S Knight, Ronald L. Klein · 2010 · Molecular Therapy
42. Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis
    Ayumi Nishiyama, Tetsuya Niihori, Hitoshi Warita, Rumiko Izumi, Tetsuya Akiyama, Masaaki Kato, Naoki Suzuki, Yoko Aoki, Masashi Aoki · 2017 · Neurobiology of Aging
43. Prion-Like Proteins in Phase Separation and Their Link to Disease
    Macy L. Sprunger, Meredith E. Jackrel · 2021 · Biomolecules
44. MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1G93A Motor Neuron of Amyotrophic Lateral Sclerosis
    Jialing Peng, Jingrui Pan, Jingjing Mo, Ying Peng · 2022 · Oxidative Medicine and Cellular Longevity
45. CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: Protection by resveratrol but not riluzole
    Matilde Yáñez, Lucía Galán, Jorge Matías‐Guiu, Álvaro Vela, Antonio Guerrero, Antonio G. Garcı́a · 2011 · Brain Research
46. Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm
    Yuyu Song, Maria Nagy, Weiming Ni, Navneet K. Tyagi, Wayne A. Fenton, Francesc López‐Giráldez, John D. Overton, Arthur L. Horwich, Scott T. Brady · 2013 · Proceedings of the National Academy of Sciences
47. Clinical phenotypes and radiological findings in frontotemporal dementia related to TARDBP mutations
    Gianluca Floris, Giuseppe Borghero, Antonino Cannas, Francesca Di Stefano, Maria Rita Murru, Daniela Corongiu, Stefania Cuccu, Stefania Tranquilli, Maria Valeria Cherchi, Alessandra Serra et al. · 2014 · Journal of Neurology
48. Autoimmunity in Amyotrophic Lateral Sclerosis: Past and Present
    Mario Rafael Pagani, Laura Elisabeth Gonzalez, Osvaldo Daniel Uchitel · 2011 · Neurology Research International
49. RNA-Processing Protein TDP-43 Regulates FOXO-Dependent Protein Quality Control in Stress Response
    Tao Zhang, Gerard Baldie, Goran Periz, Jiou Wang · 2014 · PLoS Genetics
50. Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the Mutation
    Xuejing Wang, Shuang Ying Zhou, Xuebing Ding, Mingming Ma, Jiewen Zhang, Yue Zhou, Erxi Wu, Junfang Teng · 2015 · International Journal of Biological Sciences
51. Differential Expression of Several miRNAs and the Host Genes AATK and DNM2 in Leukocytes of Sporadic ALS Patients
    Katarina Vrabec, Emanuela Boštjančič, Blaž Koritnik, Lea Leonardis, Leja Dolenc Grošelj, Janez Zidar, Boris Rogelj, Damjan Glavač, Metka Ravnik‐Glavač · 2018 · Frontiers in Molecular Neuroscience
52. miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis
    Alessia Loffreda, Monica Nizzardo, A Arosio, Marc‐David Ruepp, Raffaele Calogero, Stefano Volinia, Marco Galasso, Caterina Bendotti, Carlo Ferrarese, Christian Lunetta et al. · 2020 · Progress in Neurobiology
53. The role of DNA damage response in amyotrophic lateral sclerosis
    Yu Sun, Annabel J. Curle, Arshad M. Haider, Gabriel Balmus · 2020 · Essays in Biochemistry
54. Glycogen Synthase Kinase 3β Involvement in Neuroinflammation and Neurodegenerative Diseases
    Teresa Gianferrara, Eleonora Cescon, Ilenia Grieco, Giampiero Spalluto, Stephanie Federico · 2022 · Current Medicinal Chemistry
55. Amyotrophic lateral sclerosis caused by TARDBP mutations: from genetics to TDP-43 proteinopathy
    Rubika Balendra, Jemeen Sreedharan, Martina Hallegger, Raphaëlle Luisier, Hilal Ahmed Lashuel, Jenna M. Gregory, Rickie Patani · 2025 · The Lancet Neurology
56. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations
    Mattéa J. Finelli, Kevin X. Liu, Yixing Wu, Peter L. Oliver, Kay Elizabeth Davies · 2015 · Human Molecular Genetics
57. RNA‐binding proteins implicated in neurodegenerative diseases
    Mark Cookson · 2016 · Wiley Interdisciplinary Reviews - RNA
58. Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function
    Bernadett Kalmár, Linda Greensmith · 2017 · Frontiers in Molecular Neuroscience
59. Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases
    Ioana L. Dobra, Serhii Pankivskyi, Anastasiia Samsonova, David Pastré, Loïc Hamon · 2018 · Current Neurology and Neuroscience Reports
60. The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications
    Wenting Guo, Tijs Vandoorne, Jolien Steyaert, Kim A. Staats, Ludo Van Den Bosch · 2020 · Brain
61. Mitophagy Regulates Neurodegenerative Diseases
    Xufeng Cen, Manke Zhang, Mengxin Zhou, Lingzhi Ye, Hongguang Xia · 2021 · Cells
62. On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia
    Felix Geser, David Prvulovic, Laurence O’Dwyer, Orla M. Hardiman, Peter Bede, Arun L.W. Bokde, John Q. Trojanowski, Harald Juergen Hampel · 2011 · Progress in Neurobiology
63. Recent Advances in the Genetics of the ALS-FTLD Complex
    Huw R. Morris, Adrian J. Waite, Nigel M. Williams, James Neal, Derek J. Blake · 2012 · Current Neurology and Neuroscience Reports
64. Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS
    Hui Dong, L. Xu, L. Wu, xinying wang, W. Duan, H. Li, C. Li · 2014 · Neuroscience
65. Motor neuron–immune interactions: the vicious circle of ALS
    Ana G. Barbeito, Pinar Mesci, Séverine Boillée · 2010 · Journal of Neural Transmission
66. Primary fibroblasts cultures reveal TDP-43 abnormalities in amyotrophic lateral sclerosis patients with and without SOD1 mutations
    Mario Sabatelli, Marcella Zollino, Amelia Conte, Alessandra Del Grande, Giuseppe Marangi, Matteo Lucchini, Massimiliano Mirabella A, Ângela Romano, Roberto Piacentini, Giulia Bisogni et al. · 2015 · Neurobiology of Aging
67. A patient carrying a homozygous p.A382T TARDBP missense mutation shows a syndrome including ALS, extrapyramidal symptoms, and FTD
    Giuseppe Borghero, Gianluca Floris, Antonino Cannas, Maria Giovanna Marrosu, Maria Rita Murru, Emanuela Costantino, Leslie D. Parish, Maura Pugliatti, Anna Ticca, Bryan J. Traynor et al. · 2011 · Neurobiology of Aging
68. In the swim of things: recent insights to neurogenetic disorders from zebrafish
    Edor Kabashi, Nathalie Champagne, Edna Brustein, Pierre Drapeau · 2010 · Trends in Genetics
69. Folding of the RNA Recognition Motif (RRM) Domains of the Amyotrophic Lateral Sclerosis (ALS)-linked Protein TDP-43 Reveals an Intermediate State
    Brian C. Mackness, Meme T. Tran, Shannan P. McClain, C. Robert Matthews, Jill A. Zitzewitz · 2014 · Journal of Biological Chemistry
70. Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study
    Safa Al‐Sarraj, Andrew King, M. S. Cleveland, Pierre‐François Pradat, Andrea M. Corse, Jeffrey D. Rothstein, Peter Leigh, Bams Abila, Stewart Bates, Jens Würthner et al. · 2014 · Acta Neuropathologica Communications
71. Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis
    Paul C. Trippier, Kevin Tianmeng Zhao, Susan G. Fox, Isaac T. Schiefer, Radhia Benmohamed, Jason M. Moran, Donald R. Kirsch, Richard I. Morimoto, Richard B. Silverman · 2014 · ACS Chemical Neuroscience
72. Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis
    Sei-Kyoung Park, Joo Y. Hong, Fatih Arslan, Vydehi Kanneganti, Basant Kumar Patel, Alex Tietsort, Elizabeth M.H. Tank, Xingli Li, Sami J. Barmada, Susan Weiss Liebman · 2017 · PLoS Genetics
73. Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells
    Xuejiao Sun, Jianyuan Song, Hailong Huang, Hong Chen, Kun Xi Qian · 2018 · Stem Cell Research & Therapy
74. Glia-specific autophagy dysfunction in ALS
    Laura Strohm, Christian Behrends · 2019 · Seminars in Cell and Developmental Biology
75. Role of RNA Binding Proteins with prion-like domains in muscle and neuromuscular diseases
    Gina Picchiarelli, Luc Dupuis · 2020 · Cell Stress
76. Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy
    Julian R. Thorpe, Helen Tang, Joseph Atherton, Nigel J. Cairns · 2008 · Journal of Neural Transmission
77. TDP-43 M311V mutation in familial amyotrophic lateral sclerosis
    Robin Lemmens, Valérie Race, Nicole Hersmus, Gert Matthijs, Ludo Van Den Bosch, Philip Van Damme, Bénédicte Dubois, Susanne E. Boonen, An Goris, Wim Robberecht · 2009 · Journal of Neurology Neurosurgery & Psychiatry
78. Amyotrophic lateral sclerosis: an update on recent genetic insights
    Yohei Iguchi, Masahisa Katsuno, Kensuke Ikenaka, Shinsuke Ishigaki, Gen Sobue · 2013 · Journal of Neurology
79. The Role of VCP Mutations in the Spectrum of Amyotrophic Lateral Sclerosis—Frontotemporal Dementia
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80. Molecular Dissection of TDP-43 as a Leading Cause of ALS/FTLD
    Yoshitaka Tamaki, Makoto Urushitani · 2022 · International Journal of Molecular Sciences
81. Progranulin and TDP-43: Mechanistic Links and Future Directions
    Samir Kumar‐Singh · 2011 · Journal of Molecular Neuroscience
82. Neurodegeneration as an RNA disorder
    Rory Johnson, Wendy J. Noble, Gian Gaetano Tartaglia, Noel J. Buckley · 2012 · Progress in Neurobiology
83. Recent insights into the molecular genetics of dementia
    Rosa Rademakers, Anne Rovelet‐Lecrux · 2009 · Trends in Neurosciences
84. A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese
    Aritoshi Iida, Atsushi Takahashi, Michiaki Kubo, Susumu Saito, Naoya Hosono, Yozo Ohnishi, Kazuma Kiyotani, Taisei Mushiroda, Masahiro Nakajima, Kouichi Ozaki et al. · 2011 · Human Molecular Genetics
85. Selective vulnerability of motoneuron and perturbed mitochondrial calcium homeostasis in amyotrophic lateral sclerosis: implications for motoneurons specific calcium dysregulation
    Manoj K. Jaiswal · 2014 · Molecular and Cellular Therapies
86. Saliva in Health and Disease
    Mahvash Navazesh · 2020 · Springer eBooks
87. An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models
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88. State-of-the-Art Fluorescence Fluctuation-Based Spectroscopic Techniques for the Study of Protein Aggregation
    Akira Kitamura, Masataka Kinjo · 2018 · International Journal of Molecular Sciences
89. The Effect of Resveratrol on Neurodegenerative Disorders: Possible Protective Actions Against Autophagy, Apoptosis, Inflammation and Oxidative Stress
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90. Nuclear TAR DNA Binding Protein 43 Expression in Spinal Cord Neurons Correlates With the Clinical Course in Amyotrophic Lateral Sclerosis
    Hisae Sumi, Shinsuke Kato, Yuko Mochimaru, Harutoshi Fujimura, Masaki Etoh, Saburo Sakoda · 2008 · Journal of Neuropathology & Experimental Neurology
91. Molecular Dissection of TDP-43 Proteinopathies
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92. Identification of 2 Loci at Chromosomes 9 and 14 in a Multiplex Family With Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
    Ilse Gijselinck, Sebastiaan Engelborghs, Githa Maes, Ivy Cuijt, Karin Peeters, Maria Mattheijssens, Geert Joris, Patrick P Cras, Jean‐Jacques Martin, Peter P. De Deyn et al. · 2010 · Archives of Neurology
93. Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice
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94. Phase separation of low-complexity domains in cellular function and disease
    Jiwon Lee, Hana Cho, Ilmin Kwon · 2022 · Experimental & Molecular Medicine
95. Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response
    Frédérique Larroquette, Lesley Seto, Perrine Gaub, Brishna Kamal, DEEANN E. WALLIS, Roxanne Larivière, Joanne Vallée, Richard Robitaille, Hiroshi Tsuda · 2015 · Human Molecular Genetics
96. Screening for TARDBP mutations in Japanese familial amyotrophic lateral sclerosis
    Masaki Kamada, Hirofumi Maruyama, Eiji I. Tanaka, Hiroyuki Morino, Reika Wate, Hidefumi Ito, Hirofumi Kusaka, Yuji Kawano, Tetsuro Miki, Hiroyuki Nodera et al. · 2009 · Journal of the Neurological Sciences
97. Extensive molecular genetic survey of Taiwanese patients with amyotrophic lateral sclerosis
    Bing‐Wen Soong, Kon‐Ping Lin, Yuh-Cherng Guo, Chou‐Ching K. Lin, Pei‐Chien Tsai, Yi‐Chu Liao, Yi‐Chun Lu, Shuu‐Jiun Wang, Ching‐Piao Tsai, Yi‐Chung Lee · 2014 · Neurobiology of Aging
98. TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca2+ signaling in motor neurons
    Ruxandra Mutihac, Javier Alegre‐Abarrategui, D. Gordon, Lucy E Farrimond, Michiko Yamasaki-Mann, Kevin Talbot, Richard Wade‐Martins · 2014 · Neurobiology of Disease
99. FOSMN syndrome
    Steve Vucic, Thor D. Stein, E. Tessa Hedley‐Whyte, Stephen Reddel, Stephen H. Tisch, Katya E. Kotschet, Didier P. Cros, Matthew C. Kiernan · 2012 · Neurology
100. Old versus New Mechanisms in the Pathogenesis of ALS
     Simona Rossi, Mauro Cozzolino, Maria Teresa Carrı̀ · 2016 · Brain Pathology