TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

Cited by (1,011)

Items 101–200 of 1,011

  1. The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies
    Myungjin Jo, Shinrye Lee, Yu‐Mi Jeon, Seyeon Kim, Younghwi Kwon, Hyung‐Jun Kim · 2020 · Experimental & Molecular Medicine
  2. The genetics and neuropathology of amyotrophic lateral sclerosis
    Ammar Al‐Chalabi, Ashley Jones, Claire Troakes, Andrew King, Safa Al‐Sarraj, Leonard H. van den Berg · 2012 · Acta Neuropathologica
  3. Physiological functions and pathobiology of TDP ‐43 and FUS / TLS proteins
    Antonia Ratti, Emanuele Buratti · 2016 · Journal of Neurochemistry
  4. Long Non-Coding RNAs in the Cytoplasm
    Farooq Rashid, Abdullah Shah, Ge Shan · 2016 · Genomics Proteomics & Bioinformatics
  5. A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
    Brian S. Johnson, J. Michael McCaffery, Susan Lee Lindquist, Aaron D. Gitler · 2008 · Proceedings of the National Academy of Sciences
  6. Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death
    Sellier, Chantal, Campanari, Maria‐Letizia, Julie Corbier, Camille, Gaucherot, Angeline, Kolb‐Cheynel, Isabelle, Oulad‐Abdelghani, Mustapha, Ruffenach, Frank, Page, Adeline, Ciura, Sorana, Kabashi, Edor et al. · 2016 · The EMBO Journal
  7. Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies
    Ian R. Mackenzie, Manuela Neumann · 2016 · Journal of Neurochemistry
  8. Beyond aggregation: Pathological phase transitions in neurodegenerative disease
    Cécile Mathieu, Rohit V. Pappu, J. Paul Taylor · 2020 · Science
  9. Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
    Mercedes Prudencio, Véronique Belzil, Ranjan Batra, Christian A Ross, Tania F. Gendron, Luc Pregent, Melissa Erin Murray, Karen Overstreet, Amelia Johnston, Pamela Desaro et al. · 2015 · Nature Neuroscience
  10. PINK1/Parkin-mediated mitophagy in neurodegenerative diseases
    Jie Li, Dongming Yang, Zhiping Li, Mengyang Zhao, Dongdong Wang, Zhixin Sun, Pei Wen, Yuexin Dai, Fengting Gou, Yilan Ji et al. · 2022 · Ageing Research Reviews
  11. The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases
    Rachel E. Lackie, Andrzej Maciejewski, Valeriy G. Ostapchenko, José Marques-Lopes, Wing‐Yiu Choy, Martin L. Duennwald, Vânia F. Prado, Marco A. M. Prado · 2017 · Frontiers in Neuroscience
  12. TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
    Scotter, Emma L., Chen, Han-Jou, Shaw, Christopher E. · 2015 · Neurotherapeutics
  13. The Seeds of Neurodegeneration: Prion-like Spreading in ALS
    Magdalini Polymenidou, Don W. Cleveland · 2011 · Cell
  14. TDP-43 Pathology in Alzheimer’s Disease
    Axel D. Meneses, Shunsuke Koga, Justin O’Leary, Dennis W. Dickson, Guojun Bu, Na Zhao · 2021 · Molecular Neurodegeneration
  15. Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
    Dasuri, Kalavathi, Zhang, Le, Keller, Jeffrey N. · 2013 · Free Radical Biology and Medicine
  16. TDP-43 Is Directed to Stress Granules by Sorbitol, a Novel Physiological Osmotic and Oxidative Stressor
    Colleen M. Dewey, Basar Cenik, Chantelle F. Sephton, Daniel Robert Dries, Paul R. Mayer, Shannon K. Rich, Brett A. Johnson, Joachim Herz, Gang Yu · 2010 · Molecular and Cellular Biology
  17. Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies
    Lionel Muller Igaz, Linda K. Kwong, Alice S. Chen‐Plotkin, Matthew J. Winton, Travis L. Unger, Yan Xu, Manuela Neumann, John Q. Trojanowski, Virginia M.‐Y. Lee · 2009 · Journal of Biological Chemistry
  18. Motor Neuron dysfunction in frontotemporal dementia
    James R. Burrell, Matthew C. Kiernan, Steve Vucic, John R. Hodges · 2011 · Brain
  19. FUS‐immunoreactive inclusions are a common feature in sporadic and non‐SOD1 familial amyotrophic lateral sclerosis
    Han‐Xiang Deng, Hong Zhai, Eileen H. Bigio, Jianhua Yan, Faisal Fecto, Kaouther Ajroud, Manjari Mishra, Senda Ajroud‐Driss, Scott Heller, Robert L. Sufit et al. · 2010 · Annals of Neurology
  20. Evidence for an oligogenic basis of amyotrophic lateral sclerosis
    Marka van Blitterswijk, Michael A. van Es, Eric A. M. Hennekam, Dennis Dooijes, Wouter van Rheenen, Jelena Medic, Pierre Raymond Bourque, Helenius Jurgen Schelhaas, Anneke J. van der Kooi, Marianne de Visser et al. · 2012 · Human Molecular Genetics
  21. Understanding the role of TDP-43 and FUS/TLS in ALS and beyond
    Da Cruz, Sandrine, Cleveland, Don W · 2011 · Current Opinion in Neurobiology
  22. Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72
    Bradley F. Boeve, Khrista Boylan, Neill R. Graff‐Radford, Mariely DeJesus‐Hernandez, David S. Knopman, Otto Pedraza, Prashanthi Vemuri, David Thomas Jones, Val J. Lowe, Melissa Erin Murray et al. · 2012 · Brain
  23. Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis
    Kraemer, Brian C., Schuck, Theresa, Wheeler, Jeanna M., Robinson, Linda C., Trojanowski, John Q., Lee, Virginia M. Y., Schellenberg, Gerard D. · 2010 · Acta Neuropathologica
  24. hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
    Kohji Mori, Sven Lammich, Ian R. Mackenzie, Ignasi Forné, Sonja Zilow, Hans A. Kretzschmar, Dieter Edbauer, Jonathan Janssens, Gernot Kleinberger, Marc Cruts et al. · 2013 · Acta Neuropathologica
  25. Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB–mediated pathogenic pathways
    Vivek Swarup, Daniel Phaneuf, Nicolas Dupré, Susanne Petri, Michael Joseph Strong, Jasna Križ, Jean‐Pierre Julien · 2011 · The Journal of Experimental Medicine
  26. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
    Serio, Andrea, Bilican, Bilada, Barmada, Sami J., Ando, Dale Michael, Zhao, Chen, Siller, Rick, Burr, Karen, Haghi, Ghazal, Story, David, Nishimura, Agnes Lumi et al. · 2013 · Proceedings of the National Academy of Sciences
  27. Phosphorylated TDP-43 in Alzheimer’s disease and dementia with Lewy bodies
    Arai, Tetsuaki, Mackenzie, Ian R. A., Hasegawa, Masato, Nonoka, Takashi, Niizato, Kazhuhiro, Tsuchiya, Kuniaki, Iritani, Shuji, Onaya, Mitsumoto, Akiyama, Haruhiko · 2009 · Acta Neuropathologica
  28. Genetics of amyotrophic lateral sclerosis: an update
    Sheng Chen, Pavani Sayana, Xiaojie Zhang, Weidong Le · 2013 · Molecular Neurodegeneration
  29. Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72
    Johnathan Cooper‐Knock, Christopher Hewitt, J. Robin Highley, Alice Brockington, Antonio Milano, Somai Man, Joanne E. Martindale, Judith A. Hartley, Theresa Walsh, Catherine Gelsthorpe et al. · 2012 · Brain
  30. Inflammation in ALS/FTD pathogenesis
    McCauley, Madelyn E., Baloh, Robert H. · 2019 · Acta Neuropathologica
  31. miRNA malfunction causes spinal motor neuron disease
    Sharon Haramati, Elik Chapnik, Yehezkel Sztainberg, Raya Eilam, Raaya Zwang, Noga Gershoni, Edwina McGlinn, Patrick W. Heiser, Anne-Marie A. Wills, Itzhak Wirguin et al. · 2010 · Proceedings of the National Academy of Sciences
  32. An estimate of amyotrophic lateral sclerosis heritability using twin data
    Ammar Al‐Chalabi, Fang Fang, Martha F. Hanby, P. Nigel Leigh, Christopher E. Shaw, Weimin Ye, Frühling Vesta Rijsdijk · 2010 · Journal of Neurology Neurosurgery & Psychiatry
  33. Structural insights into TDP-43 in nucleic-acid binding and domain interactions
    P.H. Kuo, Lyudmila G. Doudeva, Y.-T. Wang, C.‐K. James Shen, Hanna S. Yuan · 2009 · Nucleic Acids Research
  34. Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
    Rachele A. Saccon, Rosie K. A. Bunton-Stasyshyn, Elizabeth Fisher, Pietro Fratta · 2013 · Brain
  35. Amyotrophic Lateral Sclerosis: An Update for 2018
    Björn Oskarsson, Tania F. Gendron, Nathan P. Staff · 2018 · Mayo Clinic Proceedings
  36. Nrf2—a therapeutic target for the treatment of neurodegenerative diseases
    Delinda A. Johnson, Jeffrey Allan Johnson · 2015 · Free Radical Biology and Medicine
  37. The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
    Crippa, Valeria, Sau, Daniela, Rusmini, Paola, Boncoraglio, Alessandra, Onesto, Elisa, Bolzoni, Elena, Galbiati, Mariarita, Fontana, Elena, Marino, Marianna, Carra, Serena et al. · 2010 · Human Molecular Genetics
  38. TDP-43 is intercellularly transmitted across axon terminals
    Feiler, Marisa S., Strobel, Benjamin, Freischmidt, Axel, Helferich, Anika M., Kappel, Julia, Brewer, Bryson M., Li, Deyu, Thal, Dietmar R., Walther, Paul, Ludolph, Albert C. et al. · 2015 · Journal of Cell Biology
  39. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
    Bilican, Bilada, Serio, Andrea, Barmada, Sami J., Nishimura, Agnes Lumi, Sullivan, Gareth J., Carrasco, Monica, Phatnani, Hemali P., Puddifoot, Clare A., Story, David, Fletcher, Judy et al. · 2012 · Proceedings of the National Academy of Sciences
  40. Emerging mechanisms of molecular pathology in ALS
    Owen M. Peters, Mehdi Ghasemi, Robert H. Brown · 2015 · Journal of Clinical Investigation
  41. Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis
    G. Scott Pesiridis, Virginia M.-Y. Lee, John Q. Trojanowski · 2009 · Human Molecular Genetics
  42. SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype–phenotype correlations
    Stéphanie Millecamps, François Salachas, Cécile Cazeneuve, Paul Gordon, Bernard Bricka, Agnès Camuzat, Léna Guillot‐Noël, Odile Russaouen, Gaëlle Bruneteau, Pierre‐François Pradat et al. · 2010 · Journal of Medical Genetics
  43. An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
    Weirui Guo, Yanbo Chen, Xiaohong Zhou, Amar N. Kar, Payal Ray, Xiaoping Chen, Elizabeth J. Rao, Mengxue Yang, Haihong Ye, Li Zhu et al. · 2011 · Nature Structural & Molecular Biology
  44. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
    Xiu Shan, Po‐Min Chiang, Donald L. Price, Philip C. Wong · 2010 · Proceedings of the National Academy of Sciences
  45. TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration
    Lina Benajiba, Isabelle Le Ber, Agnès Camuzat, Mathieu Lacoste, Catherine Thomas-Antérion, Philippe Couratier, Solenn Legallic, François Salachas, Didier Hannequin, M. Décousus et al. · 2009 · Annals of Neurology
  46. Guidelines for preclinical animal research in ALS/MND: A consensus meeting
    Albert Christian Ludolph, Caterina Bendotti, Eran Blaugrund, Adriano Chiò, Linda Greensmith, Jean‐Philippe Loeffler, Richard J. Mead, Heiko G. Niessen, Susanne Petri, Pierre‐François Pradat et al. · 2010 · Amyotrophic Lateral Sclerosis
  47. Genetics of motor neuron disorders: new insights into pathogenic mechanisms
    Patrick A. Dion, Hussein Daoud, Guy Armand Rouleau · 2009 · Nature Reviews Genetics
  48. A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells
    Matthew F. Burkhardt, Fernando J. Martinez, Sarah Wright, Carla Ramos, Dmitri Volfson, Mike J. Mason, Jeff Garnes, Vu Dang, Jeffery Lievers, Uzma Shoukat-Mumtaz et al. · 2013 · Molecular and Cellular Neuroscience
  49. Cyclin-Dependent Kinases in Brain Development and Disease
    Susan C. Su, Li‐Huei Tsai · 2011 · Annual Review of Cell and Developmental Biology
  50. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
    Annelies Van Hoecke, Lies Schoonaert, Robin Lemmens, Mieke Timmers, Kim A. Staats, Angela S. Laird, Elke Peeters, Thomas Philips, An Goris, Bénédicte Dubois et al. · 2012 · Nature Medicine
  51. Deletion of TDP-43 down-regulates Tbc1d1 , a gene linked to obesity, and alters body fat metabolism
    Po‐Min Chiang, Jonathan P. Ling, Yun Ha Jeong, Donald L. Price, Susan M. Aja, Philip C. Wong · 2010 · Proceedings of the National Academy of Sciences
  52. Rodent Models of Amyotrophic Lateral Sclerosis
    Thomas Philips, Jeffrey D. Rothstein · 2015 · Current Protocols in Pharmacology
  53. Remote Control of Gene Function by Local Translation
    Hosung Jung, Christos G. Gkogkas, Nahum Sonenberg, Christine E. Holt · 2014 · Cell
  54. Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases
    Alexander, Adanna G., Marfil, Vanessa, Li, Chris · 2014 · Frontiers in Genetics
  55. Depletion of TDP‐43 affects Drosophila motoneurons terminal synapsis and locomotive behavior
    Fabian M. Feiguin, Vinay K. Godena, Giulia Romano, Andrea D’Ambrogio, Raffaella Klima, Francisco Ernesto Baralle · 2009 · FEBS Letters
  56. TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia
    Conrad Chris Weihl, Peyker Temız, S E Miller, G Watts, Colin Smith, Mark S. Forman, Phyllis I. Hanson, Virginia E. Kimonis, Alan Pestronk · 2008 · Journal of Neurology Neurosurgery & Psychiatry
  57. Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
    Jacqueline C. Mitchell, Philip McGoldrick, Caroline A. Vance, Tibor Hortobágyi, Jemeen Sreedharan, Boris Rogelj, Elizabeth L. Tudor, Bradley N. Smith, Christian Klasen, Christopher C.J. Miller et al. · 2012 · Acta Neuropathologica
  58. Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
    Anna‐Claire Devlin, Karen Burr, Shyamanga Borooah, Joshua D. Foster, Elaine M. Cleary, Imbisaat Geti, Ludovic Vallier, Christopher E. Shaw, Siddharthan Chandran, Gareth Brian Miles · 2015 · Nature Communications
  59. Evidence of Multisystem Disorder in Whole-Brain Map of Pathological TDP-43 in Amyotrophic Lateral Sclerosis
    Felix Geser, Nicholas James Brandmeir, Linda K. Kwong, Maria Martinez‐Lage, Lauren B. Elman, Leo F. McCluskey, Sharon Xiangwen Xie, Virginia M.‐Y. Lee, John Q. Trojanowski · 2008 · Archives of Neurology
  60. Structure of pathological TDP-43 filaments from ALS with FTLD
    Diana Arseni, Masato Hasegawa, Alexey G. Murzin, Fuyuki Kametani, Makoto Arai, Mari Yoshida, Benjamin Falcon · 2021 · Nature
  61. TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells
    Claudia Colombrita, Elisa Onesto, Francesca Megiorni, Antonio Pizzuti, Francisco Ernesto Baralle, Emanuele Buratti, Vincenzo Silani, Antonia Ratti · 2012 · Journal of Biological Chemistry
  62. Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration
    Claire L. Simpson, Robin Lemmens, Katarzyna Miśkiewicz, Wendy J. Broom, Valerie K. Hansen, Paul W.J. van Vught, John E. Landers, Peter C. Sapp, Ludo Van Den Bosch, Jo Knight et al. · 2008 · Human Molecular Genetics
  63. Prion-like disorders: blurring the divide between transmissibility and infectivity
    Mimi Cushman-Nick, Brian S. Johnson, Oliver D. King, Aaron D. Gitler, James Shorter · 2010 · Journal of Cell Science
  64. Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43
    Takashi Nonaka, Fuyuki Kametani, Tetsuaki Arai, Haruhiko Akiyama, Masato Hasegawa · 2009 · Human Molecular Genetics
  65. Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids
    Sjors H. W. Scheres, Benjamin Falcon, Michel Goedert · 2023 · Nature
  66. Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72
    Melissa Erin Murray, Mariely DeJesus‐Hernandez, Nicola J. Rutherford, Matt C. Baker, Ranjan Duara, Neill R. Graff‐Radford, Zbigniew K. Wszołek, Tanis J. Ferman, Keith A. Josephs, Khrista Boylan et al. · 2011 · Acta Neuropathologica
  67. Local RNA Translation at the Synapse and in Disease: Figure 1.
    Liqun Liu‐Yesucevitz, Gary Jonathan Bassell, Aaron D. Gitler, Anne C. Hart, Eric Klann, Joel D. Richter, Stephen T. Warren, Benjamin L. Wolozin · 2011 · Journal of Neuroscience
  68. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
    Mark Y. Fang, Sebastian Markmiller, Anthony Q. Vu, Ashkan Javaherian, William E. Dowdle, Philippe Jolivet, Paul Bushway, Nicholas A. Castello, Ashmita Baral, Michelle Y. Chan et al. · 2019 · Neuron
  69. Genetics of Amyotrophic Lateral Sclerosis
    Mehdi Ghasemi, Robert H. Brown · 2017 · Cold Spring Harbor Perspectives in Medicine
  70. TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
    Matthew A. White, Eosu Kim, Amanda Duffy, Róbert Adalbert, Benjamin U. Phillips, Owen M. Peters, Jodie Stephenson, Sujeong Yang, Francesca Massenzio, Ziqiang Lin et al. · 2018 · Nature Neuroscience
  71. Gene discovery in amyotrophic lateral sclerosis: implications for clinical management
    Al-Chalabi, Ammar, van den Berg, Leonard H., Veldink, Jan · 2017 · Nature Reviews Neurology
  72. The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation
    Emanuele Buratti, Francisco Ernesto Baralle · 2010 · RNA Biology
  73. Genetics of familial amyotrophic lateral sclerosis
    Paul N. Valdmanis, Guy Armand Rouleau · 2008 · Neurology
  74. TARDBP and FUS Mutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update
    Serena Lattante, Guy Armand Rouleau, Edor Kabashi · 2013 · Human Mutation
  75. FTD and ALS: A Tale of Two Diseases
    Raffaele Ferrari, Dimitrios Kapogiannis, Edward D. Huey, Parastoo Momeni · 2011 · Current Alzheimer Research
  76. Neuropathology of amyotrophic lateral sclerosis and its variants
    Saberi, Shahram, Stauffer, Jennifer E., Schulte, Derek J., Ravits, John · 2015 · Neurologic Clinics
  77. ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
    Caroline A. Vance, Emma L. Scotter, Agnes Lumi Nishimura, Claire Troakes, Jacqueline C. Mitchell, Claudia Kathe, Hazel Urwin, Catherine Manser, Christopher C.J. Miller, Tibor Hortobágyi et al. · 2013 · Human Molecular Genetics
  78. The genetics and neuropathology of frontotemporal lobar degeneration
    Sieben, Anne, Van Langenhove, Tim, Engelborghs, Sebastiaan, Martin, Jean-Jacques, Boon, Paul, Cras, Patrick, De Deyn, Peter-Paul, Santens, Patrick, Van Broeckhoven, Christine, Cruts, Marc · 2012 · Acta Neuropathologica
  79. The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
    Adam S. Mastrocola, Sang Hwa Kim, Anthony T. Trinh, Lance A. Rodenkirch, Randal S. Tibbetts · 2013 · Journal of Biological Chemistry
  80. Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure
    Jędrzej Szymański, Justyna Janikiewicz, Bernadeta Michalska, Paulina Patalas‐Krawczyk, Mariasole Perrone, Wiesław Ziółkowski, Jerzy Duszyński, Paolo Pinton, Agnieszka Dobrzyń, Mariusz Roman Wieckowski · 2017 · International Journal of Molecular Sciences
  81. Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases
    Hong Joo Kim, J. Paul Taylor · 2017 · Neuron
  82. A Drosophila model for TDP-43 proteinopathy
    Yan Li, Payal Ray, Elizabeth J. Rao, Shi Chen, Weirui Guo, Xiaoping Chen, Elvin A. Woodruff, Kazuo Fushimi, Jane Y. Wu · 2010 · Proceedings of the National Academy of Sciences
  83. Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
    Thomas Philips, André Bento‐Abreu, Annelies Nonneman, Wanda Haeck, Kim A. Staats, Veerle Geelen, Nicole Hersmus, Benno Küsters, Ludo Van Den Bosch, Philip Van Damme et al. · 2013 · Brain
  84. Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
    Rogelj, Boris, Easton, Laura E., Bogu, Gireesh K., Stanton, Lawrence W., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Sugimoto, Yoichiro, Modic, Miha, Haberman, Nejc et al. · 2012 · Scientific Reports
  85. Differential roles of the ubiquitin proteasome system (UPS) and autophagy in the clearance of soluble and aggregated TDP-43 species
    Emma L. Scotter, Caroline A. Vance, Agnes Lumi Nishimura, Youn‐Bok Lee, Han-Jou Chen, Hazel Urwin, Valentina Sardone, Jacqueline C. Mitchell, Boris Rogelj, David Chaim Rubinsztein et al. · 2014 · Journal of Cell Science
  86. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis
    Yoshinori Nishimoto, Shinichi Nakagawa, Tetsuro Hirose, Hirotaka James Okano, Masaki Takao, Shinsuke Shibata, Satoshi Suyama, Ken-ichiro Kuwako, Takao Imai, Shigeo Murayama et al. · 2013 · Molecular Brain
  87. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions
    Javier Simón‐Sánchez, Elise G.P. Dopper, Petra E. Cohn‐Hokke, Renate K. Hukema, Nayia Nicolaou, Harro Seelaar, J. Roos A. de Graaf, Inge de Koning, Natasja M. van Schoor, Dorly J. H. Deeg et al. · 2012 · Brain
  88. Recent advances in our understanding of neurodegeneration
    Jellinger, Kurt A. · 2009 · Journal of Neural Transmission
  89. The Ageing Brain: Molecular and Cellular Basis of Neurodegeneration
    Shofiul Azam, Md. Ezazul Haque, Rengasamy Balakrishnan, In‐Su Kim, Dong‐Kug Choi · 2021 · Frontiers in Cell and Developmental Biology
  90. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
    Vivek Swarup, Daniel Phaneuf, Christine Bareil, Janice Robertson, Guy Armand Rouleau, Jasna Križ, Jean‐Pierre Julien · 2011 · Brain
  91. FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA
    Tomohiro Yamazaki, Shi Chen, Yong Yu, Biao Yan, Tyler C. Haertlein, Mónica A. Carrasco, Juan Carlos Tapia, Bo Zhai, Rita Das, Mélanie Lalancette–Hébert et al. · 2012 · Cell Reports
  92. ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations
    Radu Stoica, Sébastien Paillusson, Patricia Gómez‐Suaga, Jacqueline C. Mitchell, Dawn H. W. Lau, Emma H. Gray, Rosa M. Sancho, Gema Vizcay‐Barrena, Kurt J. De Vos, Christopher E. Shaw et al. · 2016 · EMBO Reports
  93. TDP-43 Mediates Degeneration in a Novel Drosophila Model of Disease Caused by Mutations in VCP/p97
    Gillian P. Ritson, Sara K. Custer, Brian D. Freibaum, Jake B. Guinto, Dyanna Geffel, Jennifer Moore, Waixing Tang, Matthew J. Winton, Manuela Neumann, John Q. Trojanowski et al. · 2010 · Journal of Neuroscience
  94. Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons
    Pallavi P. Gopal, Jeffrey Nirschl, Eva Klinman, Erika L.F. Holzbaur · 2017 · Proceedings of the National Academy of Sciences
  95. Genetics of amyotrophic lateral sclerosis: A review
    Stéphane Mathis, Cyril Goizet, Antoine Soulages, Jean‐Michel Vallat, Gwendal Le Masson · 2019 · Journal of the Neurological Sciences
  96. FUS mutations in amyotrophic lateral sclerosis: clinical, pathological, neurophysiological and genetic analysis
    Ian P. Blair, Kelly L. Williams, Sadaf T. Warraich, Jennifer C. Durnall, Annora Thoeng, Jim Manavis, Peter Charles Blumbergs, Steve Vucic, Matthew C. Kiernan, Garth A. Nicholson · 2009 · Journal of Neurology Neurosurgery & Psychiatry
  97. Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?
    Anaïs Aulas, Christine Vande Velde · 2015 · Frontiers in Cellular Neuroscience
  98. Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase
    John Mitchell, Praveen Paul, Han-Jou Chen, Alex G. Morris, Miles Payling, Mario Falchi, James Habgood, Stefania Panoutsou, Sabine Winkler, Veronica Tisato et al. · 2010 · Proceedings of the National Academy of Sciences
  99. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
    Jelena Scekic‐Zahirovic, Oliver Sendscheid, Hajer El Oussini, Mélanie Jambeau, Ying Sun, Sina Mersmann, Marina Wagner, Stéphane Dieterle, Jérôme Sinniger, Sylvie Dirrig‐Grosch et al. · 2016 · The EMBO Journal
  100. The involvement of microRNAs in neurodegenerative diseases
    Simona Maciotta, Mirella Meregalli, Yvan Torrente · 2013 · Frontiers in Cellular Neuroscience