Cited by 2,854RNA Research and SplicingRNA and protein synthesis mechanismsRNA regulation and disease

Blooms like it hot

Paerl, Hans W., Huisman, Jef·2008·Science

Abstract

RNA pieces in the spliceosome, has a domain V counterpart, containing a 2-nucleotide bulge located 5 base pairs away from an AGC triad (10). Formation of an analogous metalbinding platform in this region of U6 (11) may explain the apparent ability of spliceosomal RNAs to retain catalytic activity in the complete absence of the many protein components that usually accompany splicing (12). A domain V-like element could have played a major role during the RNA world era of evolution, serving as the catalytic center for RNA cleavage, transesterification, and polymerization reactions. The new structure provides a powerful starting point for future investigations of group II introns and the spliceosome. The

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Crossref · 10.1126/science.1155398

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  • Warmer temperatures can benefit some HABs via accelerated growth and an expanded realized niche.

    “Warmer temperatures can benefit some HABs via accelerated growth and an expanded realized niche (Paerl and Huisman, 2008;Fu et al., 2012;Glibert et al., 2014;Wells et al., 2015;Gobler et al., 2017).”

    From Harmful algal blooms: A climate change co-stressor in marine and freshwater ecosystems (2020) · cites this paper as Paerl and Huisman, 2008

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Authors
Paerl, H. W., & Huisman, J.
Affiliations
  • University of North Carolina at Chapel Hill (US)
  • University of Amsterdam (NL)
Venue
Science
Published
2008-04-04
Volume
320
Issue
5872
Pages
57-58
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2113162751
Cited by
2,854
References
0
Citations by year
2026: 176 · 2025: 214 · 2024: 188 · 2023: 195 · 2022: 209 · 2021: 206 · 2020: 207 · 2019: 189 · 2018: 186 · 2017: 160 · 2016: 156 · 2015: 134 · 2014: 124 · 2013: 134 · 2012: 120
FWCI
34.73
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • UvA-DARE (University of Amsterdam) (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA regulation and disease
Keywords
group II introns, spliceosome, U6 snRNA, RNA catalysis, RNA world, RNA cleavage, transesterification, RNA polymerization
MeSH terms
Cyanobacteria, Climate, Temperature, Water Microbiology, Greenhouse Effect, Ecosystem, Salinity

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