The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
BSKs Mediate Signal Transduction from the Receptor Kinase BRI1 in Arabidopsis
Open accessAbstract
Brassinosteroids (BRs) bind to the extracellular domain of the receptor kinase BRI1 to activate a signal transduction cascade that regulates nuclear gene expression and plant development. Many components of the BR signaling pathway have been identified and studied in detail. However, the substrate of BRI1 kinase that transduces the signal to downstream components remains unknown. Proteomic studies of plasma membrane proteins lead to the identification of three homologous BR-signaling kinases (BSK1, BSK2, and BSK3). The BSKs are phosphorylated by BRI1 in vitro and interact with BRI1 in vivo. Genetic and transgenic studies demonstrate that the BSKs represent a small family of kinases that activate BR signaling downstream of BRI1. These results demonstrate that BSKs are the substrates of BRI1 kinase that activate downstream BR signal transduction.
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Cites
BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
Nam, K. H., & Li, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00814-0 · Cited by 1,217
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Macho, A. P., & Zipfel, C. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.03.028 · Cited by 989
Lu, D., Wu, S., Gao, X., Zhang, Y., Shan, L., & He, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909705107 · Cited by 854
Zhang, J., Li, W., Xiang, T., Liu, Z., Laluk, K., Ding, X., Zou, Y., Gao, M., Zhang, X., Chen, S., et al. (2010) · Cell Host & Microbe · doi:10.1016/j.chom.2010.03.007 · Cited by 849
Kim, T.-W., Guan, S., Sun, Y., Deng, Z., Tang, W., Shang, J.-X., Sun, Y., Burlingame, A. L., & Wang, Z.-Y. (2009) · Nature Cell Biology · doi:10.1038/ncb1970 · Cited by 693
Self-citationYu, X., Li, L., Zola, J., Aluru, M., Ye, H., Foudree, A., Guo, H., Anderson, S., Aluru, S., Liu, P., et al. (2011) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04449.x · Cited by 666
Metadata
- Authors
- Tang, W., Kim, T.-W., Oses-Prieto, J. A., Sun, Y., Deng, Z., Zhu, S., Wang, R., Burlingame, A. L., & Wang, Z.-Y.
- Venue
- Science
- Published
- 2008-07-25
- Volume
- 321
- Issue
- 5888
- Pages
- 557-560
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1971615018
- Cited by
- 695
- References
- 1
- FWCI
- 40.11
- Type
- journal article
- Language
- en
- Open access
- green
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- Tang, W., Kim, T.-W., Oses-Prieto, J. A., Sun, Y., Deng, Z., Zhu, S., Wang, R., Burlingame, A. L., & Wang, Z.-Y. (2008). BSKs Mediate Signal Transduction from the Receptor Kinase BRI1 in Arabidopsis. Science. https://doi.org/10.1126/science.1156973
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