Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions

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Items 101–200 of 293

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3. The nucleoporin 153, a novel factor in double-strand break repair and DNA damage response
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4. High resolution imaging of changes in the structure and spatial organization of chromatin, γ-H2A.X and the MRN complex within etoposide-induced DNA repair foci
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5. Rsf-1, a Chromatin Remodeling Protein, Induces DNA Damage and Promotes Genomic Instability
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6. The NF90/NF45 Complex Participates in DNA Break Repair via Nonhomologous End Joining
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7. Serine/threonine phosphatases in the DNA damage response and cancer
   A Peng, James L. Maller · 2010 · Oncogene
8. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs
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9. Virus manipulation of cell cycle
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10. Chromatin perturbations during the DNA damage response in higher eukaryotes
    Christopher J. Bakkenist, Michael B. Kastan · 2015 · DNA repair
11. Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining
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12. Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome
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13. The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner
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14. Mechanism of elimination of phosphorylated histone H2AX from chromatin after repair of DNA double-strand breaks
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15. Tdp1 protects against oxidative DNA damage in non‐dividing fission yeast
    Samia Ben Hassine, Benoı̂t Arcangioli · 2009 · The EMBO Journal
16. Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition
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17. Phosphorylated H2AX Foci in Tumor Cells Have No Correlation with Their Radiation Sensitivities
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18. Histone modifications predispose genome regions to breakage and translocation
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19. Positive Regulation of DNA Double Strand Break Repair Activity during Differentiation of Long Life Span Cells: The Example of Adipogenesis
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20. Lac operator repeats generate a traceable fragile site in mammalian cells
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21. CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition
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22. Phosphorylation of p50 NF-κB at a Single Serine Residue by DNA-dependent Protein Kinase Is Critical for VCAM-1 Expression upon TNF Treatment
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23. Establishment of a replication fork barrier following induction of DNA binding in mammalian cells
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24. HIV-1 Vpr Induces the K48-Linked Polyubiquitination and Proteasomal Degradation of Target Cellular Proteins To Activate ATR and Promote G 2 Arrest
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25. Not All DDRs Are Created Equal: Non-Canonical DNA Damage Responses
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26. Histone H3 K56 acetylation, chromatin assembly, and the DNA damage checkpoint
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27. Models for chromosomal replication‐independent non‐B DNA structure‐induced genetic instability
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28. Collaborator of ARF (CARF) Regulates Proliferative Fate of Human Cells by Dose-dependent Regulation of DNA Damage Signaling
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29. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling
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30. Mechanisms of ATR-mediated checkpoint signalling
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31. DNA Ligase I Deficiency Leads to Replication-Dependent DNA Damage and Impacts Cell Morphology without Blocking Cell Cycle Progression
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32. Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells
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33. LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells
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36. Assembly of multiprotein complexes that control genome function
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37. Multivalent interaction of ESCO2 with the replication machinery is required for sister chromatid cohesion in vertebrates
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38. Residual γH2AX foci predict local tumour control after radiotherapy
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39. Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin
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40. Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours
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41. Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin
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42. Signal Transduction, Ageing and Disease
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43. Controversial aspects of oncogene-induced senescence
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44. Modulation of the DNA-damage response to HZE particles by shielding
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45. Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing
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46. Targeting Mouse Double Minute 2: Current Concepts in DNA Damage Repair and Therapeutic Approaches in Cancer
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47. The ATM regulated DNA damage response pathway as a chemo- and radiosensitisation target
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48. The Viral Oncoprotein Tax Sequesters DNA Damage Response Factors by Tethering MDC1 to Chromatin
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49. Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling
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50. The heat-induced γ-H2AX response does not play a role in hyperthermic cell killing
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51. Limited nucleotide pools restrict Epstein–Barr virus-mediated B-cell immortalization
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52. Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
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53. S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response
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54. Retinoblastoma Loss Modulates DNA Damage Response Favoring Tumor Progression
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55. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus
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56. An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells
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57. The Tumor Suppressor PML Specifically Accumulates at RPA/Rad51-Containing DNA Damage Repair Foci but Is Nonessential for DNA Damage-Induced Fibroblast Senescence
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58. Taming Tricky DSBs: ATM on duty
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59. Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response
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60. Kinetics of γ-H2AX induction and removal in bone marrow and testicular cells of mice after X-ray irradiation
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61. Marker-free genetic manipulations in yeast using CRISPR/CAS9 system
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62. Artemis is a negative regulator of p53 in response to oxidative stress
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63. An ATM–Chk2–INCENP pathway activates the abscission checkpoint
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64. BMI-1 regulates DNA end resection and homologous recombination repair
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65. Telomere-Mediated Effects on Melanogenesis and Skin Aging
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66. LRIK interacts with the Ku70–Ku80 heterodimer enhancing the efficiency of NHEJ repair
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67. Defective DNA repair and increased chromatin binding of DNA repair factors in Down syndrome fibroblasts
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68. DNA Damage Signaling Is Induced in the Absence of Epstein—Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA
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75. Tip60-ing the balance in DSB repair
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