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Receptor-Like Kinase ACR4 Restricts Formative Cell Divisions in the Arabidopsis Root
Abstract
During the development of multicellular organisms, organogenesis and pattern formation depend on formative divisions to specify and maintain pools of stem cells. In higher plants, these activities are essential to shape the final root architecture because the functioning of root apical meristems and the de novo formation of lateral roots entirely rely on it. We used transcript profiling on sorted pericycle cells undergoing lateral root initiation to identify the receptor-like kinase ACR4 of Arabidopsis as a key factor both in promoting formative cell divisions in the pericycle and in constraining the number of these divisions once organogenesis has been started. In the root tip meristem, ACR4 shows a similar action by controlling cell proliferation activity in the columella cell lineage. Thus, ACR4 function reveals a common mechanism of formative cell division control in the main root tip meristem and during lateral root initiation.
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Cited by
Arabidopsis lateral root development: an emerging story
Péret, B., De Rybel, B., Casimiro, I., Benková, E., Swarup, R., Laplaze, L., Beeckman, T., & Bennett, M. J. (2009) · Trends in Plant Science · doi:10.1016/j.tplants.2009.05.002 · Cited by 818
Self-citationSeo, P. J., Xiang, F., Qiao, M., Park, J.-Y., Lee, Y. N., Kim, S.-G., Lee, Y.-H., Park, W. J., & Park, C.-M. (2009) · Plant Physiology · doi:10.1104/pp.109.144220 · Cited by 657
Lateral root development in Arabidopsis: fifty shades of auxin
Lavenus, J., Goh, T., Roberts, I., Guyomarc’h, S., Lucas, M., De Smet, I., Fukaki, H., Beeckman, T., Bennett, M., & Laplaze, L. (2013) · Trends in Plant Science · doi:10.1016/j.tplants.2013.04.006 · Cited by 639
Self-citationThe roots of a new green revolution
Herder, G. D., Van Isterdael, G., Beeckman, T., & De Smet, I. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.08.009 · Cited by 508
Self-citationRoot system architecture: insights from Arabidopsis and cereal crops
Smith, S., & De Smet, I. (2012) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2011.0234 · Cited by 439
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Metadata
- Authors
- De Smet, I., Vassileva, V., De Rybel, B., Levesque, M. P., Grunewald, W., Van Damme, D., Van Noorden, G., Naudts, M., Van Isterdael, G., De Clercq, R., Wang, J. Y., Meuli, N., Vanneste, S., Friml, J., Hilson, P., Jürgens, G., Ingram, G. C., Inzé, D., Benfey, P. N., & Beeckman, T.
- Venue
- Science
- Published
- 2008-10-24
- Volume
- 322
- Issue
- 5901
- Pages
- 594-597
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2069680569
- Cited by
- 370
- References
- 0
- FWCI
- 26.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- De Smet, I., Vassileva, V., De Rybel, B., Levesque, M. P., Grunewald, W., Van Damme, D., Van Noorden, G., Naudts, M., Van Isterdael, G., De Clercq, R., Wang, J. Y., Meuli, N., Vanneste, S., Friml, J., Hilson, P., Jürgens, G., Ingram, G. C., Inzé, D., Benfey, P. N., & Beeckman, T. (2008). Receptor-Like Kinase ACR4 Restricts Formative Cell Divisions in the Arabidopsis Root. Science. https://doi.org/10.1126/science.1160158
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