The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
De Novo Formation of a Subnuclear Body
Abstract
The mammalian cell nucleus contains structurally stable functional compartments. We show here that one of them, the Cajal body (CB), can be formed de novo. Immobilization on chromatin of both CB structural components, such as coilin, and functional components of the CB, such as the SMN complex, spliceosomal small nuclear ribonucleoproteins (RNPs), small nucleolar RNPs, and small Cajal body–specific RNPs, is sufficient for the formation of a morphologically normal and apparently functional CB. Biogenesis of the CB does not follow a hierarchical assembly pathway and exhibits hallmarks of a self-organizing structure.
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Cites
Nuclear organization of the genome and the potential for gene regulation
Fraser, P., & Bickmore, W. (2007) · Nature · doi:10.1038/nature05916 · Cited by 734
The structure and function of small nucleolar ribonucleoproteins
Reichow, S. L., Hamma, T., Ferre-D'Amare, A. R., & Varani, G. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkl1172 · Cited by 413
Cited by
Compositional Control of Phase-Separated Cellular Bodies
Banani, S. F., Rice, A. M., Peeples, W. B., Lin, Y., Jain, S., Parker, R., & Rosen, M. K. (2016) · Cell · doi:10.1016/j.cell.2016.06.010 · Cited by 1,246
Boulon, S., Westman, B. J., Hutten, S., Boisvert, F.-M., & Lamond, A. I. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.024 · Cited by 1,103
α‐Synuclein aggregation nucleates through liquid‐liquid phase separation
Ray, S., Singh, N., Kumar, R., Patel, K., Pandey, S., Datta, D., Mahato, J., Panigrahi, R., Navalkar, A., Mehra, S., et al. (2020) · Nature Chemistry · doi:10.1038/s41557-020-0465-9 · Cited by 863
Han, T. W., Kato, M., Xie, S., Wu, L. C., Mirzaei, H., Pei, J., Chen, M., Xie, Y., Allen, J., Xiao, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.016 · Cited by 767
Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly
Webster, M., Witkin, K. L., & Cohen-Fix, O. (2009) · Journal of Cell Science · doi:10.1242/jcs.037333 · Cited by 416
Metadata
- Authors
- Kaiser, T. E., Intine, R. V., & Dundr, M.
- Venue
- Science
- Published
- 2008-12-12
- Volume
- 322
- Issue
- 5908
- Pages
- 1713-1717
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2107252117
- Cited by
- 247
- References
- 2
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kaiser, T. E., Intine, R. V., & Dundr, M. (2008). De Novo Formation of a Subnuclear Body. Science. https://doi.org/10.1126/science.1165216
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
