Developmental Patterning by Mechanical Signals in Arabidopsis
Abstract
A central question in developmental biology is whether and how mechanical forces serve as cues for cellular behavior and thereby regulate morphogenesis. We found that morphogenesis at the Arabidopsis shoot apex depends on the microtubule cytoskeleton, which in turn is regulated by mechanical stress. A combination of experiments and modeling shows that a feedback loop encompassing tissue morphology, stress patterns, and microtubule-mediated cellular properties is sufficient to account for the coordinated patterns of microtubule arrays observed in epidermal cells, as well as for patterns of apical morphogenesis.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Boundary cells between flower primordia and the SAM show a tangential orientation of cortical microtubules parallel to the direction of maximal stress.
“Indeed, boundary cells between flower primordia and the SAM show a tangential orientation of cortical microtubules parallel to the direction of maximal stress (Hamant et al., 2008).”
From <i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems (2016) · cites this paper as Hamant et al., 2008
Cell form and the pattern of cell division in boundary zones are at least partially determined by mechanical stress resulting from variations in growth rate and cell expansion in different regions of the shoot apex.
“Cell form and the pattern of cell division in boundary zones are at least partially determined by mechanical stress that results from variations in growth rate and cell expansion in different regions of the shoot apex (Hamant et al., 2008).”
From <i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems (2016) · cites this paper as Hamant et al., 2008
Cited by
Sorted by citations
The Cell Biology of Cellulose Synthesis
McFarlane, H. E., Döring, A., & Persson, S. (2014) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050213-040240 · Cited by 623 · see citing works
Auxin Perception--Structural Insights
Calderon-Villalobos, L. I., Tan, X., Zheng, N., & Estelle, M. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005546 · Cited by 177 · see citing works
<i>Divide et impera</i>: boundaries shape the plant body and initiate new meristems
Wang, Q., Hasson, A., Rossmann, S., & Theres, K. (2016) · New Phytologist · doi:10.1111/nph.13641 · Cited by 106 · see citing works
- Authors
- Hamant, O., Heisler, M. G., Jönsson, H., Krupinski, P., Uyttewaal, M., Bokov, P., Corson, F., Sahlin, P., Boudaoud, A., Meyerowitz, E. M., Couder, Y., & Traas, J.
- Affiliations
- École Normale Supérieure de Lyon (FR)
- INRA, Laboratoire de Reproduction et Développement des Plantes, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.
- Corresponding author
- Hamant, Olivier
- Heisler, Marcus G.
- Meyerowitz, Elliot M.
- Couder, Yves
- Traas, Jan
- ORCID
- Venue
- Science
- Published
- 2008-12-12
- Volume
- 322
- Issue
- 5908
- Pages
- 1650-1655
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2040370123
- Cited by
- 985
- References
- 0
- Citations by year
- 2026: 49 · 2025: 51 · 2024: 55 · 2023: 70 · 2022: 51 · 2021: 64 · 2020: 52 · 2019: 71 · 2018: 60 · 2017: 54 · 2016: 46 · 2015: 45 · 2014: 62 · 2013: 61 · 2012: 51
- FWCI
- 20.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- HAL (submittedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- mechanical cues, mechanical stress, morphogenesis, shoot apex, microtubule cytoskeleton, microtubule arrays, epidermal cells, feedback loops, tissue morphology, Arabidopsis thaliana, plant development
- MeSH terms
- Cell Wall, Cellulose, Dinitrobenzenes, Microtubules, Models, Biological, Morphogenesis, Pressure, Stress, Mechanical, Sulfanilamides, Arabidopsis, Meristem, Plant Shoots, Plant Stems, Plant Epidermis, Microfibrils, Cell Shape, Tubulin Modulators
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
