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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

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Genetic Mapping in Human Disease

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

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Viral Infection of Engrafted Human Islets Leads to Diabetes

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The Genetic Basis of Graves Disease

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International Union of Basic and Clinical Pharmacology. XCVI. Pattern Recognition Receptors in Health and Disease

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The African-American population with a low allele frequency of SNP rs1990760 (T allele) in IFIH1 predicts less IFN-beta expression and potential vulnerability to COVID-19 infection

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Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis

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Endogenous Retroelements and the Host Innate Immune Sensors

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Association Mapping in Plant Genomes

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Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?

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Recurrent and Prolonged Infections in a Child with a Homozygous IFIH1 Nonsense Mutation

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Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes

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Investigation and Functional Characterization of Rare Genetic Variants in the Adipose Triglyceride Lipase in a Large Healthy Working Population

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Genes Affecting β-Cell Function in Type 1 Diabetes

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Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

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Environmental Triggering of Type 1 Diabetes Autoimmunity

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Interferon Induced with Helicase C Domain 1 (IFIH1) and Virus-Induced Autoimmunity: A Review

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The selective footprints of viral pressures at the human RIG-I-like receptor family

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Experimental branch warming alters tall tree leaf phenology and acorn production

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Efficient and Cost Effective Population Resequencing by Pooling and In-Solution Hybridization

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Population Genetics of IFIH1: Ancient Population Structure, Local Selection, and Implications for Susceptibility to Type 1 Diabetes

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Protection against or triggering of Type 1 diabetes? Different roles for viral infections

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Genetic contribution to common epilepsies

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Lessons from the mouse: potential contribution of bystander lymphocyte activation by viruses to human type 1 diabetes

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Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility

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Genetic data: The new challenge of personalized medicine, insights for rheumatoid arthritis patients

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Genetics of Infectious and Inflammatory Diseases: Overlapping Discoveries from Association and Exome-Sequencing Studies

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No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis

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Induction of an Antiviral State and Attenuated Coxsackievirus Replication in Type III Interferon-Treated Primary Human Pancreatic Islets

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Tests for Genetic Interactions in Type 1 Diabetes

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Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

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Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM

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Genetic polymorphism studies in periodontitis and Fcγ receptors

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The interplay of autoimmunity and insulin resistance in type 1 diabetes.

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Exome sequencing identifies novel rheumatoid arthritis-susceptible variants in the BTNL2

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Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus

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A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation

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Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity

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Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes

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Loss-of-function mutations E6 27X and I923V of IFIH1 are associated with lower poly(I:C)–induced interferon-β production in peripheral blood mononuclear cells of type 1 diabetes patients

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Genes Associated with SLE Are Targets of Recent Positive Selection

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In search of critical dsRNA targets of ADAR1

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TYK2 Promoter Variant and Diabetes Mellitus in the Japanese

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Genetic associations in type I interferon related pathways with autoimmunity

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Rare coding variants in ALPL are associated with low serum alkaline phosphatase and low bone mineral density

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Rare-Variant Genome-Wide Association Studies: A New Frontier in Genetic Analysis of Complex Traits

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The Folate Cycle As a Cause of Natural Killer Cell Dysfunction and Viral Etiology in Type 1 Diabetes

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Self RNA Sensing by RIG-I–like Receptors in Viral Infection and Sterile Inflammation

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Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art

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Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes

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Prevention or acceleration of type 1 diabetes by viruses

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Estimation of kinship coefficient in structured and admixed populations using sparse sequencing data

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Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level

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Genetic architecture of quantitative traits and complex diseases

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Type I Diabetes Mellitus: Genetic Factors and Presumptive Enteroviral Etiology or Protection

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Common ground: shared risk factors for type 1 diabetes and celiac disease

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From virus to inflammation: Mechanisms of RIG-I-induced IL-1β production

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Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virus

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Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes

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Emerging Roles of MHC Class I Region-Encoded E3 Ubiquitin Ligases in Innate Immunity

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The Thousand Polish Genomes—A Database of Polish Variant Allele Frequencies

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Infection With Viruses From Several Families Triggers Autoimmune Diabetes in LEW.1WR1 Rats

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Potential role of type I interferon in the pathogenic process leading to type 1 diabetes

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Rare-Variant Studies to Complement Genome-Wide Association Studies

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Enterovirus RNA in Peripheral Blood May Be Associated with the Variants of rs1990760, a Common Type 1 Diabetes Associated Polymorphism in IFIH1

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TLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetes

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The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations

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Type 1 diabetes: genes associated with disease development

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Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis

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Converging Evidence Implicates the Abnormal MicroRNA System in Schizophrenia

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Whole-genome expression analyses of type 2 diabetes in human skin reveal altered immune function and burden of infection

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Cytosolic Nucleic Acid Sensors in Inflammatory and Autoimmune Disorders

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The A Allele of the rs1990760 Polymorphism in the IFIH1 Gene Is Associated with Protection for Arterial Hypertension in Type 1 Diabetic Patients and with Expression of This Gene in Human Mononuclear Cells

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The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations

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Molecular genetics of atrial fibrillation

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Enteroviruses and Parechoviruses

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RIG-I-Like Receptors Evolved Adaptively in Mammals, with Parallel Evolution at LGP2 and RIG-I

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Genome‐wide association studies (GWAS): impact on elucidating the aetiology of diabetes

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Interferon induced with helicase C domain 1 (IFIH1; MDA5)

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Cumulative effect of IFIH1 variants and increased gene expression associated with type 1 diabetes

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IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

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The association between the IFIH1 locus and type 1 diabetes

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Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes

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