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The Initial Stages of Template-Controlled CaCO 3 Formation Revealed by Cryo-TEM
Abstract
Biogenic calcium carbonate forms the inorganic component of seashells, otoliths, and many marine skeletons, and its formation is directed by an ordered template of macromolecules. Classical nucleation theory considers crystal formation to occur from a critical nucleus formed by the assembly of ions from solution. Using cryotransmission electron microscopy, we found that template-directed calcium carbonate formation starts with the formation of prenucleation clusters. Their aggregation leads to the nucleation of amorphous nanoparticles in solution. These nanoparticles assemble at the template and, after reaching a critical size, develop dynamic crystalline domains, one of which is selectively stabilized by the template. Our findings have implications for template-directed mineral formation in biological as well as in synthetic systems.
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Citations
Cited by
Liu, Y., Ai, K., & Lu, L. (2014) · Chemical Reviews · doi:10.1021/cr400407a · Cited by 4,794
Crystallization by particle attachment in synthetic, biogenic, and geologic environments
De Yoreo, J. J., Gilbert, P. U. P. A., Sommerdijk, N. A. J. M., Penn, R. L., Whitelam, S., Joester, D., Zhang, H., Rimer, J. D., Navrotsky, A., Banfield, J. F., et al. (2015) · Science · doi:10.1126/science.aaa6760 · Cited by 2,137
Self-citationA Review of Classical and Nonclassical Nucleation Theories
Karthika, S., Radhakrishnan, T. K., & Kalaichelvi, P. (2016) · Crystal Growth & Design · doi:10.1021/acs.cgd.6b00794 · Cited by 868
Habraken, W. J. E. M., Tao, J., Brylka, L. J., Friedrich, H., Bertinetti, L., Schenk, A. S., Verch, A., Dmitrovic, V., Bomans, P. H. H., Frederik, P. M., et al. (2013) · Nature Communications · doi:10.1038/ncomms2490 · Cited by 821
Self-citationIn situ TEM imaging of CaCO 3 nucleation reveals coexistence of direct and indirect pathways
Nielsen, M. H., Aloni, S., & De Yoreo, J. J. (2014) · Science · doi:10.1126/science.1254051 · Cited by 741
Metadata
- Authors
- Pouget, E. M., Bomans, P. H. H., Goos, J. A. C. M., Frederik, P. M., de With, G., & Sommerdijk, N. A. J. M.
- Venue
- Science
- Published
- 2009-03-13
- Volume
- 323
- Issue
- 5920
- Pages
- 1455-1458
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2026791619
- Cited by
- 913
- References
- 0
- FWCI
- 31.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pouget, E. M., Bomans, P. H. H., Goos, J. A. C. M., Frederik, P. M., de With, G., & Sommerdijk, N. A. J. M. (2009). The Initial Stages of Template-Controlled CaCO 3 Formation Revealed by Cryo-TEM. Science. https://doi.org/10.1126/science.1169434
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