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Cited by 398

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Discovery of Swine as a Host for the Reston ebolavirus

Barrette, Roger W., Metwally, Samia A., Rowland, Jessica M., Xu, Lizhe, Zaki, Sherif R., Nichol, Stuart T., Rollin, Pierre E., Towner, Jonathan S., Shieh, Wun-Ju, Batten, Brigid, Sealy, Tara K., Carrillo, Consuelo, Moran, Karen E., Bracht, Alexa J., Mayr, Gregory A., Sirios-Cruz, Magdalena, Catbagan, Davinio P., Lautner, Elizabeth A., Ksiazek, Thomas G., White, William R., McIntosh, Michael T.·2009·Science

Abstract

Not Reston at All: Reston ebolavirus is named, mistakenly perhaps, for Reston, Virginia, where it was discovered in the 1970s in imported macaques. After some alarm it was found not to be virulent in humans, uniquely among the ebola viruses, which are characteristically fatal causing a horrific spectrum of symptoms. Using a panviral detection assay, Reston ebolavirus has been rediscovered by Barrette et al. (p. 204 ) in domesticated pigs in the Philippines in association with other viruses that cause respiratory illness. The strains involved are closely related to the original macaque strain and, given how little variance there is among the viruses, it appears that it is freely circulating between these species possibly, like several other zoonotic viruses, having a reservoir in bats. Serological assays indicated that farm workers have become infected, although no obvious symptoms of human disease have been reported.

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Metadata

Authors
Barrette, R. W., Metwally, S. A., Rowland, J. M., Xu, L., Zaki, S. R., Nichol, S. T., Rollin, P. E., Towner, J. S., Shieh, W.-J., Batten, B., Sealy, T. K., Carrillo, C., Moran, K. E., Bracht, A. J., Mayr, G. A., Sirios-Cruz, M., Catbagan, D. P., Lautner, E. A., Ksiazek, T. G., White, W. R., & McIntosh, M. T.
Venue
Science
Published
2009-07-10
Volume
325
Issue
5937
Pages
204-206
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2167972491
Cited by
398
References
0
FWCI
23.45
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Discovery of Swine as a Host for the Reston ebolavirus. https://app.cochat.ai/papers/10.1126/science.1172705
The paper
Barrette, R. W., Metwally, S. A., Rowland, J. M., Xu, L., Zaki, S. R., Nichol, S. T., Rollin, P. E., Towner, J. S., Shieh, W.-J., Batten, B., Sealy, T. K., Carrillo, C., Moran, K. E., Bracht, A. J., Mayr, G. A., Sirios-Cruz, M., Catbagan, D. P., Lautner, E. A., Ksiazek, T. G., . . . McIntosh, M. T. (2009). Discovery of Swine as a Host for the Reston ebolavirus. Science. https://doi.org/10.1126/science.1172705

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.