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Cited by 134

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Rab35 Controls Actin Bundling by Recruiting Fascin as an Effector Protein

Zhang, Jun, Fonovic, Marko, Suyama, Kaye, Bogyo, Matthew, Scott, Matthew P.·2009·Science
DOI 10.1126/science.1174921
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Abstract

Fascin-Actin Rab Bristles: Rab proteins have diverse functions in directing intracellular traffic and may also affect development. Zhang et al. (p. 1250 ) show that during Drosophila development Rab35 influences the development of bristles, neurosensory structures built upon bundled actin. Rab35 also caused massive actin-rich filopodia protrusions from cultured cells. Activated Rab35 interacted directly with fascin, an actin filament bundling protein, to colocalize near the plasma membrane. When Rab35 was engineered to interact with the surface of mitochondria, it stimulated localized actin assembly in a fascin-dependent manner. Thus, fascin is a Rab35 effector protein that links membrane trafficking regulation to cytoskeleton assembly during development.

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Crossref · 10.1126/science.1174921

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  • RAB35 regulates endosomal exit for cell surface recycling, in part through controlling localised actin dynamics and phosphoinositide metabolism.

    “RAB35 itself regulates endosomal exit for cell surface recycling95–99, in part through controlling localised actin dynamics and phosphoinositide metabolism100,101.”

    From Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation (2025) · cites this paper as [100]

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Research works printed but not linked: 25

  1. 10.1016/j.cell.2007.11.011 · DOI
  2. 10.1038/ncb1007-1110 · DOI
  3. 10.1016/0092-8674(83)90202-7 · DOI
  4. 10.1016/j.ceb.2005.11.002 · DOI
  5. 10.1083/jcb.200305143 · DOI
  6. 10.1083/jcb.135.5.1291 · DOI
  7. 10.1091/mbc.E03-03-0158 · DOI
  8. 10.1042/BST0330627 · DOI
  9. 10.1038/nrm1500 · DOI
  10. 10.1534/genetics.106.066761 · DOI
  11. 10.1074/jbc.M800056200 · DOI
  12. 10.1016/j.febslet.2009.03.012 · DOI
  13. 10.1073/pnas.0601617103 · DOI · Paper page
  14. 10.1016/S0076-6879(01)29073-9 · DOI
  15. 10.1091/mbc.10.12.4177 · DOI
  16. 10.1083/jcb.200603013 · DOI
  17. 10.5858/2007-131-742-FEIDLB · DOI
  18. 10.1136/jcp.2005.032730 · DOI
  19. Kostopoulou E., et al.., Histol. Histopathol. 23, 935 (2008).18498068
  20. 10.1016/j.modgep.2004.04.012 · DOI
  21. 10.1083/jcb.130.3.629 · DOI
  22. 10.1083/jcb.125.2.369 · DOI
  23. 10.1016/j.cub.2006.07.020 · DOI · Paper page
  24. 10.1038/emboj.2008.54 · DOI
  25. 10.1074/jbc.M801070200 · DOI

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Metadata

Authors
Zhang, J., Fonovic, M., Suyama, K., Bogyo, M., & Scott, M. P.
Affiliations
  • Departments of Developmental Biology, Genetics, and Bioengineering and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Department of Pathology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2009-09-04
Volume
325
Issue
5945
Pages
1250-1254
ISSN
  • 0036-8075
  • 1095-9203
DOI
10.1126/science.1174921
Cited by
134
References
0
Language
en

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