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Cited by 2,088

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Actin, a Central Player in Cell Shape and Movement

Open access
Pollard, Thomas D., Cooper, John A.·2009·Science

Abstract

The protein actin forms filaments that provide cells with mechanical support and driving forces for movement. Actin contributes to biological processes such as sensing environmental forces, internalizing membrane vesicles, moving over surfaces, and dividing the cell in two. These cellular activities are complex; they depend on interactions of actin monomers and filaments with numerous other proteins. Here, we present a summary of the key questions in the field and suggest how those questions might be answered. Understanding actin-based biological phenomena will depend on identifying the participating molecules and defining their molecular mechanisms. Comparisons of quantitative measurements of reactions in live cells with computer simulations of mathematical models will also help generate meaningful insights.

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Metadata

Authors
Pollard, T. D., & Cooper, J. A.
Venue
Science
Published
2009-11-27
Volume
326
Issue
5957
Pages
1208-1212
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2154465669
Cited by
2,088
References
3
FWCI
39.88
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Actin, a Central Player in Cell Shape and Movement. https://app.cochat.ai/papers/10.1126/science.1175862
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Pollard, T. D., & Cooper, J. A. (2009). Actin, a Central Player in Cell Shape and Movement. Science. https://doi.org/10.1126/science.1175862

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.