The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Cooperation Between Translating Ribosomes and RNA Polymerase in Transcription Elongation
Open accessAbstract
Transcription and Translation in Train: In bacteria, translation of messenger RNA into proteins by the ribosome usually begins soon after the ribosome binding site emerges from RNA polymerase. Now there is evidence for direct coupling between transcription and translation in bacteria. Proshkin et al. (p. 504 ; see the Perspective by Roberts ) show that the trailing ribosome controls the rate of transcription by preventing RNA polymerase from spontaneous backtracking, which allows precise adjustment of transcriptional yield to translational needs under various growth conditions. Burmann et al. (p. 501 ; see the Perspective by Roberts ) provide a potential mechanism for coupling by showing that the transcription factor NusG, which binds RNA polymerase through its amino-terminal domain, competitively binds either a ribosomal protein or the Rho transcription termination factor through its carboxy-terminal domain. Rho binding might occur after release of the ribosome from messenger RNA, thus linking termination of transcription and translation.
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Cites
Ribosome Structure and the Mechanism of Translation
Ramakrishnan, V. (2002) · Cell · doi:10.1016/s0092-8674(02)00619-0 · Cited by 938
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Control of Transcription Termination
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A structural understanding of the dynamic ribosome machine
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Self-citationTranslation is a non-uniform process
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The Mechanism of Intrinsic Transcription Termination
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Self-citationA Ratchet Mechanism of Transcription Elongation and Its Control
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Cited by
Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis
Nicolas, P., Mäder, U., Dervyn, E., Rochat, T., Leduc, A., Pigeonneau, N., Bidnenko, E., Marchadier, E., Hoebeke, M., Aymerich, S., et al. (2012) · Science · doi:10.1126/science.1206848 · Cited by 910
Nascent transcript sequencing visualizes transcription at nucleotide resolution
Churchman, L. S., & Weissman, J. S. (2011) · Nature · doi:10.1038/nature09652 · Cited by 823
Rolfe, M. D., Rice, C. J., Lucchini, S., Pin, C., Thompson, A., Cameron, A. D. S., Alston, M., Stringer, M. F., Betts, R. P., Baranyi, J., et al. (2012) · Journal of Bacteriology · doi:10.1128/jb.06112-11 · Cited by 711
Genome‐scale models of metabolism and gene expression extend and refine growth phenotype prediction
O'Brien, E. J., Lerman, J. A., Chang, R. L., Hyduke, D. R., & Palsson, B. Ø. (2013) · Molecular Systems Biology · doi:10.1038/msb.2013.52 · Cited by 471
Evolution of multisubunit RNA polymerases in the three domains of life
Werner, F., & Grohmann, D. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2507 · Cited by 431
Metadata
- Authors
- Proshkin, S., Rahmouni, A. R., Mironov, A., & Nudler, E.
- Venue
- Science
- Published
- 2010-04-23
- Volume
- 328
- Issue
- 5977
- Pages
- 504-508
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2076353383
- Cited by
- 561
- References
- 27
- FWCI
- 17.13
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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