Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Maurano, Matthew T., Humbert, Richard, Rynes, Eric, Thurman, Robert E., Haugen, Eric, Wang, Hao, Reynolds, Alex P., Sandstrom, Richard, Qu, Hongzhu, Brody, Jennifer, Shafer, Anthony, Neri, Fidencio, Lee, Kristen, Kutyavin, Tanya, Stehling-Sun, Sandra, Johnson, Audra K., Canfield, Theresa K., Giste, Erika, Diegel, Morgan, Bates, Daniel, Hansen, R. Scott, Neph, Shane, Sabo, Peter J., Heimfeld, Shelly, Raubitschek, Antony, Ziegler, Steven, Cotsapas, Chris, Sotoodehnia, Nona, Glass, Ian, Sunyaev, Shamil R., Kaul, Rajinder, Stamatoyannopoulos, John A.·2012·Science
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Items 801–900 of 1,024
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- Linking genome variants to disease: scalable approaches to test the functional impact of human mutationsGregory M. Findlay · 2021 · Human Molecular Genetics
- The promise of enhancer-associated long noncoding RNAs in cardiac regenerationSamir Ounzain, Thierry Pedrazzini · 2015 · Trends in Cardiovascular Medicine
- Genes and environments in schizophrenia: The different pieces of a manifold puzzleJános Réthelyi, Judit Benkovits, István Bitter · 2013 · Neuroscience & Biobehavioral Reviews
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- Identifying noncoding risk variants using disease-relevant gene regulatory networksLong Gao, Yasin Uzun, Peng Gao, Bing He, Xiaoke Ma, Jiahui Wang, Shizhong Han, Kai Tan · 2018 · Nature Communications
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- Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brainCindy H. Wen, Michael P. Margolis, Rujia Dai, Pan Zhang, Pawel F. Przytycki, Daniel Vo, Arjun Bhattacharya, Nana Matoba, Miao Tang, Chuan Jiao et al. · 2024 · Science
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- Spectacle: fast chromatin state annotation using spectral learningJimin Song, Kevin C Chen · 2015 · Genome biology
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- Correlation between Reversal of DNA Methylation and Clinical Symptoms in Psoriatic Epidermis Following Narrow-Band UVB PhototherapyXiaolian Gu, Elisabet Nylander, Philip John Coates, Robin Fåhræus, Karin Nylander · 2015 · Journal of Investigative Dermatology
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- Global characterization of copy number variants in epilepsy patients from whole genome sequencingJean Monlong, Simon Girard, Caroline Meloche, Maxime Cadieux‐Dion, Danielle Molinari Andrade, Ron G. Lafrenière, Micheline Gravel, Dan Spiegelman, Alexandre Dionne‐Laporte, Cyrus G. Boelman et al. · 2018 · PLoS Genetics
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- Multicenter integrated analysis of noncoding CRISPRi screensDavid Yao, Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R. Doughty, Idan Gabdank, Henri Schmidt et al. · 2024 · Nature Methods
- Lessons and implications from association studies and post-GWAS analyses of cervical cancerDan Chen, Ulf B Gyllensten · 2014 · Trends in Genetics
- Genetic Determinants of P Wave Duration and PR SegmentNiek Verweij, Irene Mateo Leach, Malou van den Boogaard, Dirk Jan van Veldhuisen, Vincent M. Christoffels, LifeLines Cohort Study, Hans L. Hillege, Wiek H. van Gilst, Phil Barnett, Rudolf A. de Boer et al. · 2014 · Circulation Cardiovascular Genetics
- Survival and Evolution of CRISPR–Cas System in Prokaryotes and Its ApplicationsMuhammad Abu Bakr Shabbir, Haihong Hao, Muhammad Zubair Shabbir, Hafiz Iftikhar Hussain, Iqbal Zahid, Saeed Ahmed, Adeel Sattar, Mujahid Iqbal, Jun Li, Zonghui Yuan · 2016 · Frontiers in Immunology
- A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cellsGurdeep Singh, Shanelle Mullany, Sakthi D. Moorthy, Richard Zhang, Tahmid Mehdi, Ruxiao Tian, Andrew G. Duncan, Alan M Moses, Jennifer A. Mitchell · 2021 · Genome Research
- Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stress-related psychiatric disordersKlengel, Torsten, Binder, Elisabeth B · 2013 · Epigenomics
- A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veteransKimbrel, Nathan A., Garrett, Melanie E., Dennis, Michelle F., Hauser, Michael A., Ashley-Koch, Allison E., Beckham, Jean C. · 2018 · Psychiatry Research
- Systematic druggable genome‐wide Mendelian randomization identifies therapeutic targets for sarcopeniaKang‐Fu Yin, Ting Chen, Xiaojing Gu, Wei‐Ming Su, Zheng Jiang, Si‐Jia Lu, Bei Cao, Li‐Yi Chi, Xia Gao, Yong‐Ping Chen · 2024 · Journal of Cachexia Sarcopenia and Muscle
- Transposable elements and psychiatric disordersGuia Guffanti, Simona Gaudi, James H. Fallon, Janet L. Sobell, Steven G. Potkin, Carlos N. Pato, Fabio M. Macciardi · 2014 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- CRISPR-Cas9 Genome Editing of a Single Regulatory Element Nearly Abolishes Target Gene Expression in Mice—Brief ReportHan Yu, Orazio J. Slivano, Christine K. Christie, Albert W. Cheng, Joseph M. Miano · 2014 · Arteriosclerosis Thrombosis and Vascular Biology
- Genomic architecture of asthma differs by sexTesfaye Mersha Baye, Lisa Joy Martin, Jocelyn M. Biagini Myers, Melinda Butsch Kovacic, Hua He, Mark Lindsey, Umasundari Sivaprasad, Weiguo Chen, Gurjit K. Khurana Hershey · 2015 · Genomics
- Common variants in DRD2 are associated with sleep duration: the CARe consortiumBrian E. Cade, Daniel J. Gottlieb, Diane S. Lauderdale, David Alan Bennett, Aron S. Buchman, Sarah G. Buxbaum, Philip L. De Jager, Daniel S. Evans, Tibor Fülöp, Sina A. Gharib et al. · 2015 · Human Molecular Genetics
- Allele-specific transcription factor binding to common and rare variants associated with disease and gene expressionMarco Cavalli, Gang Pan, Helena Nord, Ola Wallerman, Emelie Wallén Arzt, Olof Berggren, Ingegerd Elvers, Maija‐Leena Eloranta, Lars Rönnblom, Kerstin Lindblad‐Toh et al. · 2016 · Human Genetics
- Incorporating Functional Annotations for Fine-Mapping Causal Variants in a Bayesian Framework Using Summary StatisticsChen, Wenan, McDonnell, Shannon K, Thibodeau, Stephen N, Tillmans, Lori S, Schaid, Daniel J · 2016 · Genetics
- Genetic risk factors for the development of pulmonary disease identified by genome‐wide associationRobert Hall, Ian P. Hall, Ian Sayers · 2018 · Respirology
- TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expressionQuanyi Zhao, Robert C. Wirka, Trieu Nguyen, Manabu Nagao, Paul P. Cheng, Clint L. Miller, Juyong Brian Kim, Milos Pjanic, Thomas Quertermous · 2019 · Genome Medicine
- Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactionsSarah Rennie, Maria Dalby, Lucas van Duin, Robin Andersson · 2018 · Nature Communications
- SNP rs17079281 Decreases Lung Cancer Risk Through Creating an YY1-Binding Site to Suppress DCBLD1 ExpressionYu Wang, Rongna Ma, Ben Liu, Jinyu Kong, Hongyan Lin, Xiao Yu, Ruoyang Wang, Lei Li, Ming Gao, Baosen Zhou et al. · 2019 · Oncogene
- Unravelling the complex genetics of common kidney diseases: from variants to mechanismsKatie Marie Sullivan, Katalin Suszták · 2020 · Nature Reviews Nephrology
- LDpred-funct: incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data setsCarla Márquez‐Luna, Steven Gazal, Po‐Ru Loh, Samuel Sungil Kim, Nicholas A. Furlotte, Adam Auton, Alkes L. Price · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulationGusev, Alexander, Shi, Huwenbo, Kichaev, Gleb, Pomerantz, Mark, Li, Fugen, Long, Henry W., Ingles, Sue A., Kittles, Rick A., Strom, Sara S., Rybicki, Benjamin A. et al. · 2016 · Nature Communications
- Epigenomics of autoimmune diseasesBhawna Gupta, R. David Hawkins · 2015 · Immunology and Cell Biology
- Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine NeuronsSarah A. McClymont, Paul W. Hook, Alexandra I. Soto, Xylena Reed, William Law, Samuel J. Kerans, Eric L. Waite, Nicole Briceno, Joseph F. Thole, Michael G. Heckman et al. · 2018 · The American Journal of Human Genetics
- Inside the stemness engine: Mechanistic links between deregulated transcription factors and stemness in cancerEgle-Helene Ervin, Rhiannon French, Chao‐Hui Chang, Siim Pauklin · 2022 · Seminars in Cancer Biology
- Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral bloodPaola Benaglio, Jacklyn M. Newsome, Jee Yun Han, Joshua Chiou, Anthony Aylward, Sierra Corban, Michael Miller, Mei-Lin Okino, Jaspreet Kaur, Sebastian Preißl et al. · 2023 · PLoS Genetics
- Integrative analysis of transcriptome dynamics during human craniofacial development identifies candidate disease genesTara N. Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Scarpa Wilderman, Kelsey R. Robinson, Tia Gordon, Jill Anne Rosenfeld, Jennifer VanOudenhove, Daryl A. Scott, Elizabeth J. Leslie et al. · 2023 · Nature Communications
- VISTA Enhancer browser: an updated database of tissue-specific developmental enhancersMichael Kosicki, Fotis A. Baltoumas, Guy Kelman, Joshua Boverhof, Yeongshnn Ong, Laura Cook, Diane E. Dickel, Georgios A. Pavlopoulos, Len A. Pennacchio, Axel Visel · 2024 · Nucleic Acids Research
- Genetic determinants of haemolysis in sickle cell anaemiaJacqueline N. Milton, Helen Rooks, Emma Drašar, Elizabeth L. McCabe, Clinton T. Baldwin, Efi Melista, Victor R. Gordeuk, Mehdi syed Nouraie, Gregory R. Kato, Caterina P. Minniti et al. · 2013 · British Journal of Haematology
- BET-ting on chromatin-based therapeutics for heart failureSaptarsi M. Haldar, Timothy A. McKinsey · 2014 · Journal of Molecular and Cellular Cardiology
- Determining causality and consequence of expression quantitative trait lociAlexis J. Battle, Stephen B. Montgomery · 2014 · Human Genetics
- A hidden Markov random field-based Bayesian method for the detection of long-range chromosomal interactions in Hi-C dataZheng Quan Xu, Guosheng Zhang, Fulai Jin, Mengjie Chen, Terrence S. Furey, Patrick F. Sullivan, Zhaohui Steve Qin, Ming Hu, Yun Li · 2015 · Bioinformatics
- Context-specific effects of genetic variants associated with autoimmune diseaseIris H. Jonkers, Cisca Wijmenga · 2017 · Human Molecular Genetics
- Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter AssaysPeter J. Castaldi, Feng Guo, Dandi Qiao, Fei Du, Zun Zar Chi Naing, Yan Li, Betty Pham, Tarjei Sigurd Mikkelsen, Michael H. Cho, Edwin K. Silverman et al. · 2018 · American Journal of Respiratory and Critical Care Medicine
- Identification of the primate-specific gene BTN3A2 as an additional schizophrenia risk gene in the MHC lociYong Wu, Rui Bi, Chunhua Zeng, Changguo Ma, Chunli Sun, Jingzheng Li, Xiao Xiao, Ming Li, Dengfeng Zhang, Ping Zheng et al. · 2019 · EBioMedicine
- A novel k -mer set memory (KSM) motif representation improves regulatory variant predictionYuchun Guo, Kevin Tian, Haoyang Zeng, Xiaoyun Guo, David Kenneth Gifford · 2018 · Genome Research
- Genome-wide chromatin accessibility analysis unveils open chromatin convergent evolution during polyploidization in cottonJinlei Han, Damar Lizbeth López-Arredondo, Guangrun Yu, Yankun Wang, Baohua Wang, Sarah Brooke Wall, Xin Zhang, Hui Fang, Alfonso Carlos Barragán-Rosillo, Xiaoping Pan et al. · 2022 · Proceedings of the National Academy of Sciences
- A Prox1 enhancer represses haematopoiesis in the lymphatic vasculatureJan Kazenwadel, Parvathy Venugopal, Anna Oszmiana, John Toubia, Luis Arriola‐Martinez, Virginia Panara, Sandra Piltz, Chris Brown, Wanshu Ma, ANDREAS W. SCHREIBER et al. · 2023 · Nature
- Non-coding RNA in control of gene regulatory programs in cardiac development and diseaseLeonne E. Philippen, Ellen Dirkx, Paula A. da Costa Martins, León J. De Windt · 2015 · Journal of Molecular and Cellular Cardiology
- Eukaryotic enhancers: common features, regulation, and participation in diseasesMaksim Erokhin, Yegor S Vassetzky, Pavel G Georgiev, Darya Chetverina · 2015 · Cellular and Molecular Life Sciences
- Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association StudiesLipika R. Pal, John Moult · 2015 · Journal of Molecular Biology
- Inferring causality and functional significance of human coding DNA variantsShamil R. Sunyaev · 2012 · Human Molecular Genetics
- Multi-scale chromatin state annotation using a hierarchical hidden Markov modelEugenio Marco, Wouter R. A. Meuleman, Jialiang Huang, Kimberly Glass, Luca Pinello, Jianrong Wang, M Kellis, Guo‐Cheng Yuan · 2017 · Nature Communications
- Using the structure of genome data in the design of deep neural networks for predicting amyotrophic lateral sclerosis from genotypeBojian Yin, Marleen Balvert, Rick A. A. van der Spek, Bas E. Dutilh, Sander M. Bohté, Jan Herman Veldink, Alexander Schönhuth · 2019 · Bioinformatics
- Spatial chromatin architecture alteration by structural variations in human genomes at the population scaleMichał Sadowski, Agnieszka Kraft, Przemysław Szałaj, Michał Wlasnowolski, Zhonghui Tang, Yijun Ruan, Dariusz Plewczyński · 2019 · Genome biology
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- Simultaneous quantification of mRNA and protein in single cells reveals post-transcriptional effects of genetic variationChristian Brion, Sheila Lutz, Frank Wolfgang Albert · 2020 · eLife
- Functional evaluation of genetic variants associated with endometriosis near GREB1Fung, Jenny N., Holdsworth-Carson, Sarah J., Sapkota, Yadav, Zhao, Zhen Zhen, Jones, Lincoln, Girling, Jane E., Paiva, Premila, Healey, Martin, Nyholt, Dale R., Rogers, Peter A. W. et al. · 2015 · Human Reproduction
- Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genesAndrew D. Skol, Segun C. Jung, Ana Marija Sokovic, Siquan Chen, Sarah Fazal, Olukayode Ayodeji Sosina, Poulami P Borkar, Amy Lin, Maria S. Sverdlov, Dingcai Cao et al. · 2020 · eLife
- Rewriting regulatory DNA to dissect and reprogram gene expressionGabriella E. Martyn, Michael T. Montgomery, Hank Jones, Katherine Guo, Benjamin R. Doughty, Johannes Linder, Deepa Bisht, Fan Xia, Xiangmeng Shawn Cai, Ziwei Chen et al. · 2023 · Cell
- Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLsXiaoling Zhang, Hinco Jasper Gierman, Daniel A Levy, Andrew S. Plump, Radu Dobrin, Harald H.H. Göring, Joanne E. Curran, Matthew P. Johnson, John Blangero, Stuart K. Kim et al. · 2014 · BMC Genomics
- Distal enhancers: new insights into heart development and diseaseJoseph A. Wamstad, Xinchen Wang, Olukunle O. Demuren, Laurie A. Boyer · 2013 · Trends in Cell Biology
- Decoding a Signature-Based Model of Transcription Cofactor Recruitment Dictated by Cardinal Cis-Regulatory Elements in Proximal Promoter RegionsChristopher W. Benner, Sergiy Konovalov, Carlos Mackintosh, Kasey R. Hutt, Rieka Stunnenberg, Ivan García-Bassets · 2013 · PLoS Genetics
- Enhancer alterations in cancer: a source for a cell identity crisisKen J. Kron, Swneke Donovan Bailey, Mathieu Lupien · 2014 · Genome Medicine
- A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian DisordersWang, Xuting, Campbell, Michelle R., Lacher, Sarah E., Cho, Hye-Youn, Wan, Ma, Crowl, Christopher L., Chorley, Brian N., Bond, Gareth L., Kleeberger, Steven R., Slattery, Matthew et al. · 2016 · Cell Reports
- Explaining the disease phenotype of intergenic SNP through predicted long range regulationJingqi Chen, Weidong Tian · 2016 · Nucleic Acids Research
- Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel diseaseClaartje Meddens, Magdaléna Harakaľová, Noortje A. M. van den Dungen, Hassan Foroughi Asl, Hemme J. Hijma, Edwin P. J. G. Cuppen, Johan Björkegren, Folkert Wouter Asselbergs, Edward E. S. Nieuwenhuis, Michal Mokrý · 2016 · Genome biology
- Mapping eQTLs with RNA-seq reveals novel susceptibility genes, non-coding RNAs and alternative-splicing events in systemic lupus erythematosusChristopher A. Odhams, Andrea Cortini, Lingyan Chen, Amy L. Roberts, Ana Viñuela, Alfonso Buil, Kerrin S. Small, Emmanouil T. Dermitzakis, David Lester Morris, Timothy James Vyse et al. · 2016 · Human Molecular Genetics
- A review of CRISPR associated genome engineering: application, advances and future prospects of genome targeting tool for crop improvementShadma Afzal, Preeti Sirohi, Nand K. Singh · 2020 · Biotechnology Letters
- Population genetics of rare variants and complex diseasesRyan D. Hernandez, Maher, MC, Uricchio, LH, Torgerson, DG, Hernandez, RD · 2013 · eScholarship (California Digital Library)
- A human brain vascular atlas reveals diverse cell mediators of Alzheimer’s disease riskYang, Andrew C., Vest, Ryan T., Kern, Fabian, Lee, Davis P., Maat, Christina A., Losada, Patricia M., Chen, Michelle B., Agam, Maayan, Schaum, Nicholas, Khoury, Nathalie et al. · 2021
- Modeling Psychiatric Disorder Biology with Stem CellsDebamitra Das, Kyra L. Feuer, Marah H. Wahbeh, Dimitrios Avramopoulos · 2020 · Current Psychiatry Reports
- Novel insight into the aetiology of rheumatoid arthritis gained by a cross-tissue transcriptome-wide association studyJing Ni, Peng Wang, Kang-Jia Yin, Xiao‐Ke Yang, Han Cen, Cong Sui, Guo‐Cui Wu, Hai‐Feng Pan · 2022 · RMD Open
- Genome-wide association studies of late-onset cardiovascular diseaseJ.Gustav Smith, Christopher Newton‐Cheh · 2015 · Journal of Molecular and Cellular Cardiology
- Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding?Gregory A. Moyerbrailean, Cynthia A. Kalita, Chris T. Harvey, Xiaoquan Wen, Francesca Luca, Roger Piqué-Regi · 2016 · PLoS Genetics
- The appeasement of Doug: a synthetic approach to enhancer biologyBen J. Vincent, Javier Estrada, Angela H. DePace · 2016 · Integrative Biology
- The genetic predisposition to bronchopulmonary dysplasiaKun‐Hsing Yu, Jingjing Li, Michael P. Snyder, Gary Michael Shaw, Hugh M O'Brodovich · 2016 · Current Opinion in Pediatrics
- Coordinating Regulation of Gene Expression in Cardiovascular Disease: Interactions between Chromatin Modifiers and Transcription FactorsAshley J. Bauer, Kathleen A. Martin · 2017 · Frontiers in Cardiovascular Medicine
- Population- and individual-specific regulatory variation in SardiniaMauro Pala, Zachary Zappala, Mara Marongiu, Xin Li, Joe R. Davis, Roberto Cusano, Francesca Crobu, Kimberly R. Kukurba, Michael J. Gloudemans, Frédéric Reinier et al. · 2017 · Nature Genetics
- Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary diseaseJarrett D. Morrow, Michael H. Cho, John Platig, Xiaobo Zhou, Dawn Lisa DeMeo, Weiliang Qiu, Bartholome Celli, Nathaniel T. Marchetti, Gerard J. Criner, Raphael Bueno et al. · 2018 · Human Genomics