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Cited by 282

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Open access
Näsvall, Joakim, Sun, Lei, Roth, John R., Andersson, Dan I.·2012·Science

Abstract

Duplicate Gene, New Tricks: The fact that functionally new genes appear is clear, but the evolutionary process that allows for a new gain of function is not well understood. Näsvall et al. (p. 384 ) present the innovation-amplification-divergence model which suggests that after gene duplication, ancestral function is maintained but that the duplicate copies can gain new function that is selected for through the accumulation of mutations or changes in expression. Experimental selection on Salmonella enterica allowed an ancestral gene to evolve new enzymatic function in fewer than 3000 generations.

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Crossref · 10.1126/science.1226521

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Metadata

Authors
Näsvall, J., Sun, L., Roth, J. R., & Andersson, D. I.
Venue
Science
Published
2012-10-19
Volume
338
Issue
6105
Pages
384-387
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2005233159
Cited by
282
References
31
FWCI
12.40
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence. https://app.cochat.ai/papers/10.1126/science.1226521
The paper
Näsvall, J., Sun, L., Roth, J. R., & Andersson, D. I. (2012). Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence. Science. https://doi.org/10.1126/science.1226521

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.