The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism
Open accessAbstract
Digit Determination: Pentadactyly has been an early and rapid innovation of tetrapods. Sheth et al. (p. 1476 ) report that a dramatic reduction in distally expressed Hox genes, in the absence of a functional morphogen signaling pathway, results in extreme polydactyly in mice. Mutant digits exhibited patterns reminiscent of the endoskeleton of fins, suggesting that an ancestral patterning mechanism has been deeply conserved in evolution.
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Citations
Cites
The chemical basis of morphogenesis
Turing, A. M. (1952) · Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences · doi:10.1098/rstb.1952.0012 · Cited by 11,733
Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation
Kondo, S., & Miura, T. (2010) · Science · doi:10.1126/science.1179047 · Cited by 1,651
Wang, B., Fallon, J. F., & Beachy, P. A. (2000) · Cell · doi:10.1016/s0092-8674(00)80678-9 · Cited by 1,014
Deep homology and the origins of evolutionary novelty
Shubin, N., Tabin, C., & Carroll, S. (2009) · Nature · doi:10.1038/nature07891 · Cited by 842
Hox genes in digit development and evolution
Zákány, J., & Duboule, D. (1999) · Cell and Tissue Research · doi:10.1007/s004410051262 · Cited by 178
Cited by
Positional Information and Pattern Formation
Wolpert, L. (2016) · Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2015.11.008 · Cited by 649
Programmed and self-organized flow of information during morphogenesis
Collinet, C., & Lecuit, T. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00318-6 · Cited by 322
The developmental basis of fingerprint pattern formation and variation
Glover, J. D., Sudderick, Z. R., Shih, B. B.-J., Batho-Samblas, C., Charlton, L., Krause, A. L., Anderson, C., Riddell, J., Balic, A., Li, J., et al. (2023) · Cell · doi:10.1016/j.cell.2023.01.015 · Cited by 136
Turing patterns in development: what about the horse part?
Marcon, L., & Sharpe, J. (2012) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2012.11.013 · Cited by 130
Self-citationAgent-based modeling of morphogenetic systems: advantages and challenges.
Glen, C. M., Kemp, M. L., & Voit, E. O. (2019) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006577 · Cited by 116
Metadata
- Authors
- Sheth, R., Marcon, L., Bastida, M. F., Junco, M., Quintana, L., Dahn, R., Kmita, M., Sharpe, J., & Ros, M. A.
- Venue
- Science
- Published
- 2012-12-14
- Volume
- 338
- Issue
- 6113
- Pages
- 1476-1480
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2076118717
- Cited by
- 348
- References
- 5
- FWCI
- 10.57
- Type
- journal article
- Language
- en
- Open access
- green
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- Sheth, R., Marcon, L., Bastida, M. F., Junco, M., Quintana, L., Dahn, R., Kmita, M., Sharpe, J., & Ros, M. A. (2012). Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism. Science. https://doi.org/10.1126/science.1226804
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