The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Offspring from Oocytes Derived from in Vitro Primordial Germ Cell–like Cells in Mice
Abstract
Artificially Induced Oocytes: In mice, male embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been shown to differentiate into primordial germ cell–like cells (PGCLCs) in vitro. Upon transplantation into testes, these PGCLCs can form fully functional sperm. Again working in mice, Hayashi et al. (p. 971 , published online 4 October) found that female ESCs and iPSCs can also differentiate into PGCLCs, which, when aggregated in reconstituted ovaries, exhibited epigenetic reprogramming and meiotic potential in vitro. Upon transplantation of the reconstituted ovaries under ovarian bursa, female PGCLCs developed into fully grown oocytes that contributed to healthy offspring upon in vitro maturation and fertilization.
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TM4: a free, open-source system for microarray data management and analysis
Saeed, A. I., Sharov, V., White, J., Li, J., Liang, W., Bhagabati, N., Braisted, J., Klapa, M., Currier, T., Thiagarajan, M., et al. (2003) · BioTechniques · doi:10.2144/03342mt01 · Cited by 4,837
Of lineage and legacy: the development of mammalian hematopoietic stem cells
Dzierzak, E., & Speck, N. A. (2008) · Nature Immunology · doi:10.1038/ni1560 · Cited by 707
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Hill, P. W. S., Leitch, H. G., Requena, C. E., Sun, Z., Amouroux, R., Roman-Trufero, M., Borkowska, M., Terragni, J., Vaisvila, R., Linnett, S., et al. (2018) · Nature · doi:10.1038/nature25964 · Cited by 272
Epigenetic inheritance through the female germ-line: The known, the unknown, and the possible
Clarke, H. J., & Vieux, K.-F. (2015) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2015.07.003 · Cited by 79
Human Germline Genome Editing: On the Nature of Our Reasons to Genome Edit
Sparrow, R. (2022) · The American Journal of Bioethics · doi:10.1080/15265161.2021.1907480 · Cited by 40
Ganjibakhsh, M., Mehraein, F., Koruji, M., Aflatoonian, R., & Farzaneh, P. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.111544 · Cited by 18
Metadata
- Authors
- Hayashi, K., Ogushi, S., Kurimoto, K., Shimamoto, S., Ohta, H., & Saitou, M.
- Venue
- Science
- Published
- 2012-11-16
- Volume
- 338
- Issue
- 6109
- Pages
- 971-975
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1988643971
- Cited by
- 767
- References
- 2
- FWCI
- 57.87
- Type
- journal article
- Language
- en
- Open access
- closed
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