Circulating Tumor Cells

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Mani, S. A., Guo, W., Liao, M.-J., Eaton, E. N., Ayyanan, A., Zhou, A. Y., Brooks, M. W., Reinhard, F., Zhang, C. C., Shipitsin, M. V., et al. (2008) · Cell · doi:10.1016/j.cell.2008.03.027 · Cited by 8,839

A Perspective on Cancer Cell Metastasis

Chaffer, C. L., & Weinberg, R. A. (2011) · Science · doi:10.1126/science.1203543 · Cited by 4,905

Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer

Cristofanilli, M., Budd, G. T., Ellis, M. J., Stopeck, A., Matera, J., Miller, M. C., Reuben, J. M., Doyle, G. V., Allard, W. J., Terstappen, L. W. M. M., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040766 · Cited by 4,602

Dissemination and growth of cancer cells in metastatic sites

Chambers, A. F., Groom, A. C., & MacDonald, I. C. (2002) · Nature reviews. Cancer · doi:10.1038/nrc865 · Cited by 4,018

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

Yu, M., Bardia, A., Wittner, B. S., Stott, S. L., Smas, M. E., Ting, D. T., Isakoff, S. J., Ciciliano, J. C., Wells, M. N., Shah, A. M., et al. (2013) · Science · doi:10.1126/science.1228522 · Cited by 2,476

Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

Bono, J. S. D., Scher, H. I., Montgomery, B., Parker, C. C., Miller, M. C., Tissing, H., Doyle, G. V., Terstappen, L. W. M. M., Pienta, K. J., & Raghavan, D. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-08-0872 · Cited by 2,189

EMT and Dissemination Precede Pancreatic Tumor Formation

Rhim, A. D., Mirek, E. T., Aiello, N. M., Maitra, A., Bailey, J. M., McAllister, F., Reichert, M., Beatty, G. L., Rustgi, A. K., Vonderheide, R. H., et al. (2012) · Cell · doi:10.1016/j.cell.2011.11.025 · Cited by 2,136

Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer

Cohen, S. J., Punt, C. J. A., Iannotti, N. O., Saidman, B. H., Sabbath, K. D., Gabrail, N. Y., Picus, J., Morse, M., Mitchell, E. P., Miller, M. C., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.8923 · Cited by 1,876

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

Stott, S. L., Hsu, C., Tsukrov, D. I., Yu, M., Miyamoto, D. T., Waltman, B. A., Rothenberg, S. M., Shah, A. M., Smas, M. E., Korir, G. K., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012539107 · Cited by 1,657

Detection of Circulating Tumor Cells Using the Attune NxT

Gruijs, M., Zeelen, C., Hellingman, T., Smit, J. N., Borm, F. J., Geert Kazemier, M., Dickhoff, C., Bahce, I., de Langen, J., Smit, E. F., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010021 · Cited by 16

Tumor Microenvironment-Inspired Glutathione-Responsive Three-Dimensional Fibrous Network for Efficient Trapping and Gentle Release of Circulating Tumor Cells

Luo, Z., He, Y., Li, M., Ge, Y., Huang, Y., Liu, X., Hou, J., & Zhou, S. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c00307 · Cited by 16

A Multifunctional Delivery System for Remodulating Cell Behaviors of Circulating Malignant Cells to Prevent Cell Fusion

Han, D., He, X., Huang, Y., Gao, M., Guo, T., Ren, X., Liao, X., Chen, X., Pang, X., & Cheng, S. (2023) · Advanced Science · doi:10.1002/advs.202303309 · Cited by 16

A Radiomics Approach to Identify Immunologically Active Tumor in Patients with Head and Neck Squamous Cell Carcinomas

Nguyen, T. M., Bertolus, C., Giraud, P., Burgun, A., Saintigny, P., Bibault, J., & Foy, J.-P. (2023) · Cancers · doi:10.3390/cancers15225369 · Cited by 15

Advances and challenges in the use of liquid biopsy in gynaecological oncology

Zhang, Y. X., & Tian, L. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e39148 · Cited by 16

Genetic analysis of circulating tumor cells in pancreatic cancer patients: A pilot study

Görner, K., Bachmann, J., Holzhauer, C., Kirchner, R., Raba, K., Fischer, J., Martignoni, M. E., Schiemann, M., & Alunni‐Fabbroni, M. (2015) · Genomics · doi:10.1016/j.ygeno.2015.02.003 · Cited by 16

Molecular prognostic prediction in liver cirrhosis

Goossens, N. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i36.10262 · Cited by 16

Circulating tumor cells: A surrogate to predict the effect of treatment and overall survival in gastric adenocarcinoma

Zhu, Y., Chen, N., Chen, M., Cui, X., Yang, H., Zhu, X., Dai, J., Gong, Y., Gu, D., Huo, X., et al. (2021) · The International Journal of Biological Markers · doi:10.1177/1724600820981972 · Cited by 16

In vitro cultures of circulating tumor cells: a potential tool to unravel drug sensitivity

Renzi, G. D., Marco, G. D., Meo, M. D., Rosso, E. D., Gazzaniga, P., & Nicolazzo, C. (2022) · Cancer Drug Resistance · doi:10.20517/cdr.2021.121 · Cited by 17

Tumor-Derived Biomarkers in Liquid Biopsy of Glioblastoma

Khristov, V., Lin, A. C., Freedman, Z., Staub, J., Shenoy, G., Mrowczynski, O., Rizk, E., Zacharia, B. E., & Connor, J. R. (2022) · World Neurosurgery · doi:10.1016/j.wneu.2022.11.012 · Cited by 16

Hydrodynamic and label-free sorting of circulating tumor cells from whole blood

Geislinger, T. M., Stamp, M. E. M., Wixforth, A., & Franke, T. (2015) · Applied Physics Letters · doi:10.1063/1.4935563 · Cited by 16

Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection

Apostolou, P., Ntanovasilis, D.-A., & Papasotiriou, I. (2017) · Journal of Biological Research - Thessaloniki · doi:10.1186/s40709-017-0068-9 · Cited by 16

Isolation of circulating plasma cells from blood of patients diagnosed with clonal plasma cell disorders using cell selection microfluidics

Kamande, J. W., Lindell, M., Witek, M. A., Voorhees, P. M., & Soper, S. A. (2018) · Integrative Biology · doi:10.1039/c7ib00183e · Cited by 16

HER2 status of CTCs by peptide-functionalized nanoparticles as the diagnostic biomarker of breast cancer and predicting the efficacy of anti-HER2 treatment

Wang, M., Liu, Y., Shao, B., Liu, X., Hu, Z., Wang, C., Li, H., Zhu, L., Li, P., & Yang, Y. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1015295 · Cited by 15

Mesenchymal-endothelial nexus in breast cancer spheroids induces vasculogenesis and local invasion in a CAM model

Li, A., Muenst, S. E., Hoffman, J., Starck, L., Sarem, M., Fischer, A., Hütter, G., & Shastri, V. P. (2022) · Communications Biology · doi:10.1038/s42003-022-04236-5 · Cited by 19

Circulating tumor cells participate in the formation of microvascular invasion and impact on clinical outcomes in hepatocellular carcinoma

Sun, B., Ji, W., Wang, W., Chen, L., Ma, J., Tang, E., Lin, M., & Zhang, X. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1265866 · Cited by 15

Serological Exosome Metabolic Biopsy of Hepatocellular Carcinoma via Designed Core–Shell Nanoparticles

Yang, C., Chen, H., Deng, C., & Sun, N. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.3c02068 · Cited by 16

Recent insights into the development of nanotechnology to detect circulating tumor cells

Viswanath, B., & Kim, S. (2016) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2016.05.026 · Cited by 15

Microfluidic chip for graduated magnetic separation of circulating tumor cells by their epithelial cell adhesion molecule expression and magnetic nanoparticle binding

Williams, P. S., Moore, L. R., Joshi, P., Goodin, M. S., Zborowski, M., & Fleischman, A. J. (2020) · Journal of Chromatography A · doi:10.1016/j.chroma.2020.461823 · Cited by 15

Interrogating the interplay of angiogenesis and immunity in metastatic colorectal cancer

Kampoli, K., Foukas, P. G., Ntavatzikos, A., Arkadopoulos, N. F., & Koumarianou, A. A. (2022) · World Journal of Methodology · doi:10.5662/wjm.v12.i1.43 · Cited by 15

PDMS micropillar-based microchip for efficient cancer cell capture

Xiao, J., He, W., Zhang, Z., Zhang, W., Cao, Y., He, R., & Chen, Y. (2015) · RSC Advances · doi:10.1039/c5ra04353k · Cited by 15

Circulating Tumor Cells: A Window to Understand Cancer Metastasis, Monitor and Fight Against Cancers

Xu, L., Shamash, J., & Lu, Y. (2015) · Journal of cancer research updates · doi:10.6000/1929-2279.2015.04.01.2 · Cited by 15

NanoVelcro-captured CTC number concomitant with enhanced serum levels of MMP7 and MMP9 enables accurate prediction of metastasis and poor prognosis in patients with lung adenocarcinoma

Sun, Y., Chen, Y., Li, S., Lei, Y., Xu, D., Jiang, N., Zhang, Y., Cao, J., & Ke, Z. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s144033 · Cited by 15

From Cancer to Immune-Mediated Diseases and Tolerance Induction: Lessons Learned From Immune Oncology and Classical Anti-cancer Treatment

Klöß, S., Dehmel, S., Braun, A. C., Parnham, M. J., Koehl, U., & Schiffmann, S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01423 · Cited by 15

Enhanced electrochemiluminescence cytosensing based on abundant oxygen vacancies contained 2D nanosheets emitter coupled with DNA device cycle-amplification

Gao, H. X., Zhang, J., Wei, X., Zhu, Q., & Wei, T. (2021) · Talanta · doi:10.1016/j.talanta.2021.122230 · Cited by 15

O 2 -(6-Oxocyclohex-1-en-1-yl)methyl diazen-1-ium-1,2-diolates: a new class of nitric oxide donors activatable by GSH/GSTπ with both anti-proliferative and anti-metastatic activities against melanoma

Bai, C., Xue, R., Wu, J., Lv, T., Luo, X., Huang, Y., Gong, Y. M., Zhang, H., Zhang, Y., & Huang, Z. (2017) · Chemical Communications · doi:10.1039/c7cc00213k · Cited by 15

Circulating tumor cells: overcoming challenges of detecting a needle in a haystack

Myrkhiyeva, Z., Seitkamal, K., Ashikbayeva, Z., Taizhanova, A., Tosi, D., & Bekmurzayeva, A. (2025) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2025.1002321 · Cited by 17

A Wireless Cytosensor Based on a Bionic Dandelion Isothermal Amplification System for Ultrasensitive Detection of Circulating Tumor Cells

Fu, Y., Li, Y., Long, Z., Dong, X., Zhang, Y., Li, K., Shen, H., Fang, H., & Cui, W. (2025) · ACS Nano · doi:10.1021/acsnano.5c03586 · Cited by 14

Circulating tumor cells: Cancer’s deadly couriers

Lim, C. T., & Hoon, D. S. �. (2014) · Physics Today · doi:10.1063/pt.3.2275 · Cited by 14

Opportunities and challenges for sample preparation and enrichment in mass spectrometry for single‐cell metabolomics

Wevers, D., Ramautar, R., Clark, C., Hankemeier, T., & Ali, A. (2023) · Electrophoresis · doi:10.1002/elps.202300105 · Cited by 15

Steric Hindrance-Mediated Enzymatic Reaction Enable Homogeneous Dual Fluorescence Indicators Aptasensing of Hepatocellular Carcinoma CTCs

Jiang, P., Zhan, Z., Peng, Y., Wu, C., Wang, Y., Wu, L., Shi, S., Ying, B., Wei, Y., Chen, P., et al. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c01624 · Cited by 14

Circulating tumor cells in the blood of poorly differentiated nasal squamous cell carcinoma patients: correlation with treatment response

Li, F., Liu, J., Song, D., Zhang, Q., Ding, N., & He, X. (2016) · Acta Oto-Laryngologica · doi:10.1080/00016489.2016.1201861 · Cited by 14

Functional, UV-curable coating for the capture of circulating tumor cells

Song, W., Li, X., Zhao, Y., Liu, C., Xu, J., Wang, H., & Zhang, T. (2019) · Biomaterials Science · doi:10.1039/c9bm00264b · Cited by 14

Liquid Biopsy Targeting Monocarboxylate Transporter 1 on the Surface Membrane of Tumor-Derived Extracellular Vesicles from Synovial Sarcoma

Yokoo, S., Fujiwara, T., Yoshida, A., Uotani, K., Morita, T., Kiyono, M., Hasei, J., Nakata, E., Kunisada, T., Iwata, S., et al. (2021) · Cancers · doi:10.3390/cancers13081823 · Cited by 14

Selective Adhesion and Switchable Release of Breast Cancer Cells via Hyaluronic Acid Functionalized Dual Stimuli-Responsive Microgel Films

Schmidt, M., Franken, A., Wilms, D., Fehm, T. N., Neubauer, H. J., & Schmidt, S. (2021) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c00586 · Cited by 14

Recent advances in blood-based and artificial intelligence-enhanced approaches for gastrointestinal cancer diagnosis

Li, L.-S., Guo, X., & Sun, K. (2021) · World Journal of Gastroenterology · doi:10.3748/wjg.v27.i34.5666 · Cited by 14

Enhanced Separation Efficiency and Purity of Circulating Tumor Cells Based on the Combined Effects of Double Sheath Fluids and Inertial Focusing

Li, B., Wei, K., Liu, Q., Sun, X.-G., Su, N., Li, W., Shang, M.-Y., Li, J., Liao, D., Li, J., et al. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.750444 · Cited by 15

Colorimetric and fluorescence detection of circulating tumor cells based on a bimetallic-organic framework

Zhang, Y., Zhang, Z., Pan, H., Chang, D., & Lin, Y. (2023) · Microchemical Journal · doi:10.1016/j.microc.2023.108621 · Cited by 14

Combined use of circulating tumor cells and salivary mRNA to detect non–small-cell lung cancer

Gu, X., He, J., & Ji, G. (2020) · Medicine · doi:10.1097/md.0000000000019097 · Cited by 14

Phenotypic Plasticity in Circulating Tumor Cells Is Associated with Poor Response to Therapy in Metastatic Breast Cancer Patients

Cohen, E. N., Jayachandran, G., Gao, H., Peabody, P., McBride, H. B., Alvarez, F. D., Kai, M., Song, J., Shen, Y., Willey, J. S., et al. (2023) · Cancers · doi:10.3390/cancers15051616 · Cited by 13

Recent advances in DNA-based molecular devices and their applications in cancer diagnosis

Yang, S., Zhu, R., Wang, S., Xiong, Y., Zhou, G., Cao, Y., & Zhao, J. T. (2023) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2023.215331 · Cited by 13

Recapitulating the Cancer Microenvironment Using Bioprinting Technology for Precision Medicine

Kim, J., Jang, J., & Cho, D. (2021) · Micromachines · doi:10.3390/mi12091122 · Cited by 13

Increased levels of N6-methyladenosine in peripheral blood RNA: a perspective diagnostic biomarker and therapeutic target for non-small cell lung cancer

Yin, H., Hong, H., Yin, P., Lu, W., Niu, S., Chen, X., Xia, Y., Jiang, P., & Huang, Z. (2022) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2022-1033 · Cited by 13

Controllable self-assembled DNA nanomachine enable homogeneous rapid electrochemical one-pot assay of lung cancer circulating tumor cells

Liu, C., Shen, X., Li, Y., Qu, R., Wang, Y., He, Y., Zhan, Z., Chen, P., & Feng, L. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115865 · Cited by 15

Unsteady particle motion in an acoustic standing wave field

Wang, S., Allen, J. S., & Ardekani, A. M. (2017) · European Journal of Computational Mechanics · doi:10.1080/17797179.2017.1321205 · Cited by 13

Liquid biopsy challenge and hope in colorectal cancer

Burz, C. C., Rosca, A., Pop, V.-V., Buiga, R., Aldea, C. O., Samaşcă, G., Silaghi, C. N., Sur, D. G., Lupan, I., & Pricopie, A. (2019) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2019.1597708 · Cited by 13

Elasticity-Modulated Microbeads for Classification of Floating Normal and Cancer Cells Using Confining Microchannels

Ren, J., Li, J., Li, Y., Xiao, P., Liu, Y., Tsang, C. M., Tsao, S. W., Lau, D., Chan, K. W. Y., & Lam, R. H. W. (2019) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b01273 · Cited by 13

Efficient Capture and Raman Analysis of Circulating Tumor Cells by Nano-Undulated AgNPs-rGO Composite SERS Substrates

Park, J., Oh, N., Nam, H., Park, J., Kim, S., Jeon, J. S., & Yang, M. (2020) · Sensors · doi:10.3390/s20185089 · Cited by 13

Deep generative models in single-cell omics

Rivero-García, I., Torres, M., & Sánchez‐Cabo, F. (2024) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2024.108561 · Cited by 13

Biofluid-Based Circulating Tumor Molecules as Diagnostic Tools for Use in Personalized Medicine

Bahassi, Y. L. E. M. (2013) · Journal of Molecular Biomarkers & Diagnosis · doi:10.4172/2155-9929.1000157 · Cited by 12

Profilierung zirkulierender Tumorzellen mit Apparaturen und Materialien der nächsten Generation

Green, B. J., Safaei, T. S., Mepham, A. H., Labib, M., Mohamadi, R. M., & Kelley, S. O. (2015) · Angewandte Chemie · doi:10.1002/ange.201505100 · Cited by 12

Unraveling Cancer Metastatic Cascade Using Microfluidics-based Technologies

Hakim, M., Kermanshah, L., Abouali, H., Hashemi, H. M., Yari, A., Khorasheh, F., Alemzadeh, I., & Vossoughi, M. (2022) · Biophysical Reviews · doi:10.1007/s12551-022-00944-8 · Cited by 13

Lipid tethering of breast tumor cells enables real-time imaging of free-floating cell dynamics and drug response

Chakrabarti, K. R., Andorko, J. I., Whipple, R. A., Zhang, P., Sooklal, E. L., Martin, S. S., & Jewell, C. M. (2016) · Oncotarget · doi:10.18632/oncotarget.7251 · Cited by 12

The Optimization of a Microfluidic CTC Filtering Chip by Simulation

Li, H., Chen, J., Du, W., Xia, Y., Wang, D., Zhao, G., & Chu, J. (2017) · Micromachines · doi:10.3390/mi8030079 · Cited by 12

Genomic Instability in Circulating Tumor Cells

Freitas, M. O., Gartner, J. G., Pozzo, A. R., & Mai, S. (2020) · Cancers · doi:10.3390/cancers12103001 · Cited by 12

The Association Between Neoadjuvant Therapy and Pathological Outcomes in Pancreatic Cancer Patients After Resection: Prognostic Significance of Microscopic Venous Invasion

Kubo, H., Ohgi, K., Sugiura, T., Ashida, R., Yamada, M., Otsuka, S., Yamazaki, K., Todaka, A., Sasaki, K., & Uesaka, K. (2022) · Annals of Surgical Oncology · doi:10.1245/s10434-022-11628-8 · Cited by 12

3D Silicon Microstructures: A New Tool for Evaluating Biological Aggressiveness of Tumor Cells

Mazzini, G., Carpignano, F., Surdo, S., Aredia, F., Panini, N., Torchio, M., Erba, E., Danova, M., Scovassi, A. I., Barillaro, G., et al. (2015) · IEEE Transactions on NanoBioscience · doi:10.1109/tnb.2015.2476351 · Cited by 12

Prognostic impact of circulating tumor cells in patients with ampullary cancer

Sun, B., Liu, H., Wang, S., Xiang, J., & Liu, X. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.26353 · Cited by 12

A Review on Nano/Microfluidic Devices for Cell Isolation Techniques: Recent Progress and Advances

Garshasbi, H. R., & Naghib, S. M. (2023) · Current Nanoscience · doi:10.2174/0115734137264742231001142853 · Cited by 11

Click chemistry-mediated enrichment of circulating tumor cells and tumor-derived extracellular vesicles for dual liquid biopsy in differentiated thyroid cancer

Feng, B. C., Wang, J., Zhang, R. Y., Wei, A. Y., Zhao, C. N., Yen, Y.-T., Ji, Y., Kim, H. Y., Ju, Y., Smalley, M. D., et al. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102431 · Cited by 11

Liquid biopsy for the management of gastrointestinal cancers

Salehnia, Z., Rezaee, D., Ehtiati, S., Bakhtiari, M., Khalilzad, M. A., & Najafi, S. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120474 · Cited by 11

A universal monoclonal antibody-aptamer conjugation strategy for selective non-invasive bioparticle isolation from blood on a regenerative microfluidic platform

Chen, Y., Yang, Y., Feng, J., Carrier, A. J., Tyagi, D., Yu, X., Wang, C.-G., Oakes, K. D., & Zhang, X. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.09.001 · Cited by 11

Identification of Atypical Circulating Tumor Cells with Prognostic Value in Metastatic Breast Cancer Patients

Lopresti, A., Boudin, L., Finetti, P., Garnier, S., Aulas, A., Liberatoscioli, M. L., Cabaud, O., Guillé, A., de Nonneville, A. T., Costa, Q. D., et al. (2022) · Cancers · doi:10.3390/cancers14040932 · Cited by 11

Ultrasonic scattering measurements of a live single cell at 86 MHz

Lee, C., Jung, H., Lam, K. H., Yoon, C., & Shung, K. K. (2015) · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · doi:10.1109/tuffc.2015.007307 · Cited by 11

Molecular Characterization of Circulating Tumor Cells: Holy Grail for Personalized Cancer Treatment?

Lianidou, E. S. (2014) · Clinical Chemistry · doi:10.1373/clinchem.2014.230144 · Cited by 11

Interaction between prostate cancer stem cells and bone microenvironment regulates prostate cancer bone metastasis and treatment resistance

Yao, L., & Zhang, X. (2022) · Journal of Cancer · doi:10.7150/jca.73143 · Cited by 10

Sequential Responsive Multifunctional Nanomicelle Effectuates Collective Elimination of Breast Cancer and Cancer Stem Cells

Wang, X., Tang, Y., Yang, L., Wang, X., & Qi, Z. (2024) · Small · doi:10.1002/smll.202404219 · Cited by 10

Circulating tumor cells in solid malignancies: From advanced isolation technologies to biological understanding and clinical relevance in early diagnosis and prognosis

Janjua, D., Chaudhary, A., Joshi, U., Tripathi, T., & Bharti, A. C. (2024) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189236 · Cited by 12

Filter‐Assisted ICP‐MS Tumor Liquid Biopsy Enabled by Dual‐Target‐Regulated Functional DNA Nanospheres Cascade Amplification

Wu, Y., Wang, Y., Li, Y., Huang, K., Chang, K., & Chen, P. (2025) · Small Methods · doi:10.1002/smtd.202500314 · Cited by 10

NOK/STYK1 promotes the genesis and remodeling of blood and lymphatic vessels during tumor progression

Liu, Y., Li, T., Hu, D. M., & Zhang, S. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.07.059 · Cited by 10

miR-638 in circulating leukaemia cells as a non-invasive biomarker in diagnosis, treatment response and MRD surveillance of acute promyelocytic leukaemia

Bai, Y., Chen, C. Y., Guo, X., Ding, T., Yang, X., Yu, J. C., Yang, J., Ruan, J., Zheng, X., & Chen, Z. (2020) · Cancer Biomarkers · doi:10.3233/cbm-190899 · Cited by 10

A nanotherapeutic approach to selectively eliminate metastatic breast cancer cells by targeting cell surface GRP78

Shin, J.-H., Kim, B., Lager, T. W., Mejia, F., Guldner, I. H., Conner, C., Zhang, S., Panopoulos, A. D., & Bilgiçer, B. (2023) · Nanoscale · doi:10.1039/d3nr00800b · Cited by 10

Emerging non‑invasive detection methodologies for lung cancer (Review)

Li, Z., Shu, J., Yang, B., Zhang, Z., Huang, J., & Chen, Y. (2020) · Oncology Letters · doi:10.3892/ol.2020.11460 · Cited by 11

Live circulating tumour cells selection on digitized self-assembled cell array (Digi-saca) chip by in-parallel/in-situ image analysis, cell capture, and cultivation

Goudar, V. S., Yeh, P.-H., Wu, S.-Y., Chu, C.-H., Lu, L., Yang, C.-H., Chiou, T.-J., & Tseng, F. (2020) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2020.128002 · Cited by 10

Sorting of circulating tumor cells based on the microfluidic device of a biomimetic splenic interendothelial slit array

Chen, J., Yang, Z., Xu, W., Yi, M., Zhong, M., Li, X., & Tian, H. (2021) · Microfluidics and Nanofluidics · doi:10.1007/s10404-021-02459-2 · Cited by 10

Ulex Europaeus Agglutinin-I-Based Magnetic Isolation for the Efficient and Specific Capture of SW480 Circulating Colorectal Tumor Cells

Tian, R., Li, X., Zhang, H., Ma, L., Zhang, H., & Wang, Z. (2022) · ACS Omega · doi:10.1021/acsomega.2c03702 · Cited by 10

Circulating biomarkers for diagnosis and therapeutic monitoring in bone metastasis

Song, M., Park, S. I., & Cho, S. W. (2023) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-022-01396-6 · Cited by 13

Biosensors: an introduction

Kalinke, C., de Oliveira, P. R., Bonacin, J. A., & Janegitz, B. C. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15380-8.00004-7 · Cited by 10

Single-cell RNA sequencing reveals spatial heterogeneity and immune evasion of circulating tumor cells

Sun, Y., Zhou, J., Fan, J., & Yang, X. (2021) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2021.0466 · Cited by 10

Cell Electrokinetic Fingerprint: A Novel Approach Based on Optically Induced Dielectrophoresis (ODEP) for In‐Flow Identification of Single Cells

Filippi, J., Casti, P., Antonelli, G., Murdocca, M., Mencattini, A., Corsi, F., D’Orazio, M., Pecora, A., Luca, M. D., Curci, G., et al. (2024) · Small Methods · doi:10.1002/smtd.202300923 · Cited by 9

First-line application of apatinib combined with S-1 based on peripheral circulating tumor cell screening to treat advanced gastric adenocarcinoma: a case report

Chen, W., Yu, J., Zhang, Y., Wang, W., Yu, W., Shi, X., Xu, Z., & Liu, H. (2019) · Annals of Translational Medicine · doi:10.21037/atm.2019.03.68 · Cited by 9

Specific cell capture and noninvasive release via moderate electrochemical oxidation of boronic ester linkage

Zhang, Q., Ouyang, J., Wang, Y., Zhai, T.-T., Wang, C., Wu, Z., Zhang, T., Wang, K., & Xia, X. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.111316 · Cited by 9

Stem Cells: Current Status and Therapeutic Implications

Reddy, K. B. (2020) · Genes · doi:10.3390/genes11111372 · Cited by 9

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Poudineh, M., Labib, M., Ahmed, S. U., Nguyen, L. N. M., Kermanshah, L., Mohamadi, R. M., Sargent, E. H., & Kelley, S. O. (2016) · Angewandte Chemie · doi:10.1002/ange.201608983 · Cited by 9

Carboxyl graphene modified PEDOT:PSS organic electrochemical transistor for in situ detection of cancer cell morphology

Song, Q., Liu, H., Wang, W., Chen, C., Cao, Y., Chen, B., Cai, B., & He, R. (2024) · Nanoscale · doi:10.1039/d3nr06190f · Cited by 9

Quantitative evaluation of dielectrophoretic separation efficiency of cancer exosomes based on fluorescence imaging

Nakabayashi, R., Koyama, R., Inaba, M., Nakano, M., & Suehiro, J. (2024) · Japanese Journal of Applied Physics · doi:10.35848/1347-4065/ad2657 · Cited by 9

MicroRNA signatures as clinical biomarkers in lung cancer

Lianidou, E. S., Markou, A., & Zavridou, M. (2015) · Current Biomarker Findings · doi:10.2147/cbf.s55358 · Cited by 9

Differential expression of minimal residual disease markers in peripheral blood and bone marrow samples from high-risk neuroblastoma patients

Yamamoto, N., Kozaki, A., Hartomo, T. B., Yanai, T., Hasegawa, D., Kawasaki, K., Kosaka, Y., Matsuo, M., Hirase, S., MORI, T., et al. (2015) · Oncology Letters · doi:10.3892/ol.2015.3710 · Cited by 9

Sensitive and specific detection of circulating tumor cells promotes precision medicine for cancer

Huang, Q., Chen, X., Jiang, W., Jin, S., Wang, X., Liu, W., Guo, S., Guo, J., & Zhao, X. (2019) · Journal of Cancer Metastasis and Treatment · doi:10.20517/2394-4722.2018.94 · Cited by 9

Single-Cell Microwell Platform Reveals Circulating Neural Cells as a Clinical Indicator for Patients with Blood-Brain Barrier Breakdown

Zhang, Y., Warden, A. R., Ahmad, K. Z., Liu, Y., He, X., Zheng, M.-Q., Huo, X., Zhi, X., Ke, Y., Li, H., et al. (2021) · Research · doi:10.34133/2021/9873545 · Cited by 9

Circulating Tumor Cells

Gazzaniga, P., Raimondi, C., Gradilone, A., Naso, G., Cortesi, E., & Frati, L. (2012) · Molecular Diagnosis & Therapy · doi:10.1007/bf03256424 · Cited by 9

High‑throughput and continuous flow isolation of rare circulating tumor cells and clusters in gastric cancer from human whole blood samples using electromagnetic vibration‑based filtration

An, X., Xue, M., Ren, F., Wang, L., Ye, Z., Li, D., Ji, Q., Ji, G., & Lu, Z. (2020) · Oncology Reports · doi:10.3892/or.2020.7567 · Cited by 9

Clinical significance of circulating tumour cells and tumour marker detection in the chemotherapeutic evaluation of advanced colorectal cancer

Shen, F., Zhu, Y., Wang, F., Cai, X., Ding, H., Zhou, F., Wang, J., Gu, H., Liu, C., & Li, Q. (2021) · Colorectal Disease · doi:10.1111/codi.15939 · Cited by 9

Bioactive metallic nanozymes-based electrochemical biosensors for biomarker detection: Progress and prospects

Tan, R., Jiang, P., Gao, N., Cai, Z., Grushevskaya, H. V., Wu, Y., He, H., He, Y., & Chang, G. (2025) · Nano Materials Science · doi:10.1016/j.nanoms.2024.07.005 · Cited by 8

Circulating lnc-LOC as a novel noninvasive biomarker in the treatment surveillance of acute promyelocytic leukaemia

Wang, G., Yan, G., Sang, K., Yang, H., Sun, N., Bai, Y., Xu, F., Zheng, X., & Chen, Z. (2022) · BMC Cancer · doi:10.1186/s12885-022-09621-1 · Cited by 8

An integrated electrochemical immunosensor based on Pd–Ir cubic nanozyme and Ketjen black for ultrasensitive detection of circulating tumor cells

Fu, X., Lu, Y., & Yang, P. (2023) · Analytical Biochemistry · doi:10.1016/j.ab.2023.115428 · Cited by 8

Biostable Double-Strand Circular Aptamers Conjugated Onto Dendrimers for Specific Capture and Inhibition of Circulating Leukemia Cells

Li, Y., Zhang, T., Huang, J., Dong, H., Xie, J., & Jia, L. (2021) · OncoTargets and Therapy · doi:10.2147/ott.s287720 · Cited by 8

Influence of the obstacles on dielectrophoresis-assisted separation in microfluidic devices for cancerous cells

Valijam, S., & Salehi, A. (2021) · Journal of the Brazilian Society of Mechanical Sciences and Engineering · doi:10.1007/s40430-021-02875-z · Cited by 8

Enhancing Prediction Performance by Add-On Combining Circulating Tumor Cell Count, CD45neg EpCAMneg Cell Count on Colorectal Cancer, Advance, and Metastasis

Chiu, S. Y., Hsieh, C., You, J., Chu, P.-Y., Hung, H., Chu, P., & Wu, M. (2021) · Cancers · doi:10.3390/cancers13112521 · Cited by 8

Microfluidics for the Isolation and Detection of Circulating Tumor Cells

Sierra-Agudelo, J., Rodriguez-Trujíllo, R., & Samitier, J. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-04039-9_16 · Cited by 8

Circulating Tumor Cells as Biomarkers

Liu, S. V., Xu, T., & Goldkorn, A. (2012) · Springer eBooks · doi:10.1007/978-1-4419-9755-5_12 · Cited by 1

Clinical Significance of Circulating Tumor Cells

Apostolopoulos, C., Giamas, G., & Stebbing, J. (2007) · Biomarkers in Medicine · doi:10.2217/17520363.1.3.341 · Cited by 14

Circulating tumor cells in oncology

Vodolazhsky, D. I., Нехаева, Т. Л., & Балдуева, И. А. (2022) · Siberian Journal of Oncology · doi:10.21294/1814-4861-2022-21-3-117-125 · Cited by 2

Circulating Tumor Cells: A Multifunctional Biomarker

Yap, T. A., Lorente, D., Omlin, A. G., Olmos, D., & Bono, J. S. D. (2014) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-2664 · Cited by 214

The biology and clinical potential of circulating tumor cells

Ložar, T., Geršak, K., Čemažar, M., Kuhar, C. G., & Jesenko, T. (2024) · Radiology and Oncology · doi:10.2478/raon-2024-0055 · Cited by 2