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Cited by 893

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

Open access
Lucifora, Julie, Xia, Yuchen, Reisinger, Florian, Zhang, Ke, Stadler, Daniela, Cheng, Xiaoming, Sprinzl, Martin F., Koppensteiner, Herwig, Makowska, Zuzanna, Volz, Tassilo, Remouchamps, Caroline, Chou, Wen-Min, Thasler, Wolfgang E., Hüser, Norbert, Durantel, David, Liang, T. Jake, Münk, Carsten, Heim, Markus H., Browning, Jeffrey L., Dejardin, Emmanuel, Dandri, Maura, Schindler, Michael, Heikenwalder, Mathias, Protzer, Ulrike·2014·Science

Abstract

Clearance of Chronic Virus: The family of mRNA-editing enzymes, APOBEC, restricts hepatitis B virus (HBV) replication. Lucifora et al. (p. 1221 , published online 20 February; see the Perspective by Shlomai and Rice ) provide evidence that specific APOBECs mediate the anti-HBV effects of host cytokines, which in turn apparently induce nuclear deaminase activity without damaging host cells. Thus, there may be potential in these findings for developing a therapeutic route to curing chronic HBV infection.

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Crossref · 10.1126/science.1243462

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Metadata

Authors
Lucifora, J., Xia, Y., Reisinger, F., Zhang, K., Stadler, D., Cheng, X., Sprinzl, M. F., Koppensteiner, H., Makowska, Z., Volz, T., Remouchamps, C., Chou, W.-M., Thasler, W. E., Hüser, N., Durantel, D., Liang, T. J., Münk, C., Heim, M. H., Browning, J. L., Dejardin, E., Dandri, M., Schindler, M., Heikenwalder, M., & Protzer, U.
Venue
Science
Published
2014-03-14
Volume
343
Issue
6176
Pages
1221-1228
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2051173965
Cited by
893
References
1
FWCI
77.30
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA. https://app.cochat.ai/papers/10.1126/science.1243462
The paper
Lucifora, J., Xia, Y., Reisinger, F., Zhang, K., Stadler, D., Cheng, X., Sprinzl, M. F., Koppensteiner, H., Makowska, Z., Volz, T., Remouchamps, C., Chou, W.-M., Thasler, W. E., Hüser, N., Durantel, D., Liang, T. J., Münk, C., Heim, M. H., Browning, J. L., . . . Protzer, U. (2014). Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA. Science. https://doi.org/10.1126/science.1243462

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.