Aging-induced type I interferon response at the choroid plexus negatively affects brain function
Baruch, Kuti, Deczkowska, Aleksandra, David, Eyal, Castellano, Joseph M., Miller, Omer, Kertser, Alexander, Berkutzki, Tamara, Barnett-Itzhaki, Zohar, Bezalel, Dana, Wyss-Coray, Tony, Amit, Ido, Schwartz, Michal·2014·Science
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- The choroid plexus and the paradox of interferons in the aging brainSuhayl S. Dhib-Jalbut · 2014 · Cytokine
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