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Cited by 913

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility

Open access
Yu, Min, Bardia, Aditya, Aceto, Nicola, Bersani, Francesca, Madden, Marissa W., Donaldson, Maria C., Desai, Rushil, Zhu, Huili, Comaills, Valentine, Zheng, Zongli, Wittner, Ben S., Stojanov, Petar, Brachtel, Elena, Sgroi, Dennis, Kapur, Ravi, Shioda, Toshihiro, Ting, David T., Ramaswamy, Sridhar, Getz, Gad, Iafrate, A. John, Benes, Cyril, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.·2014·Science

Abstract

Staying one step ahead of tumors: Cancer treatments require continual adjustment. A drug that works initially will lose its potency as the tumor acquires new mutations that allow it to bypass the drug's lethal effects. To stay ahead of the tumor, oncologists need a noninvasive way to collect tumor cells from patients over the course of their treatment. Analyzing the mutations in these samples may help them choose the right drugs as the tumors change. In a small study of breast cancer patients, Yu et al. show that rare tumor cells circulating in the blood can be captured in viable form and used for this purpose. Science , this issue p. 216

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Metadata

Authors
Yu, M., Bardia, A., Aceto, N., Bersani, F., Madden, M. W., Donaldson, M. C., Desai, R., Zhu, H., Comaills, V., Zheng, Z., Wittner, B. S., Stojanov, P., Brachtel, E., Sgroi, D., Kapur, R., Shioda, T., Ting, D. T., Ramaswamy, S., Getz, G., Iafrate, A. J., Benes, C., Toner, M., Maheswaran, S., & Haber, D. A.
Venue
Science
Published
2014-07-11
Volume
345
Issue
6193
Pages
216-220
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2012987872
Cited by
913
References
4
FWCI
32.46
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. https://app.cochat.ai/papers/10.1126/science.1253533
The paper
Yu, M., Bardia, A., Aceto, N., Bersani, F., Madden, M. W., Donaldson, M. C., Desai, R., Zhu, H., Comaills, V., Zheng, Z., Wittner, B. S., Stojanov, P., Brachtel, E., Sgroi, D., Kapur, R., Shioda, T., Ting, D. T., Ramaswamy, S., Getz, G., . . . Haber, D. A. (2014). Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. Science. https://doi.org/10.1126/science.1253533

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.