The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
Open accessAbstract
Life and death and quality control: When cells are subjected to too much stress, they curl up their toes and die. Lu et al. describe a clever strategy cells use to stay alive as long as they are not stressed for too long. The cells' quality-control machinery will activate a so-called death receptor when defective proteins accumulate within the cell, a sign of stress—but they will wait until the proteins have built up for a good long time. If stress is relieved soon enough, levels of the death receptor decay back to normal, and the cells stay alive; otherwise, R.I.P. Science , this issue p. 98
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Cites
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Self-citationER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim
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Cited by
Mechanisms, regulation and functions of the unfolded protein response
Hetz, C., Zhang, K., & Kaufman, R. J. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0250-z · Cited by 2,666
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The Unfolded Protein Response and Cell Fate Control
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Endoplasmic reticulum stress signals in the tumour and its microenvironment
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Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
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Metadata
- Authors
- Lu, M., Lawrence, D. A., Marsters, S., Acosta-Alvear, D., Kimmig, P., Mendez, A. S., Paton, A. W., Paton, J. C., Walter, P., & Ashkenazi, A.
- Venue
- Science
- Published
- 2014-07-04
- Volume
- 345
- Issue
- 6192
- Pages
- 98-101
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2078016121
- Cited by
- 567
- References
- 31
- FWCI
- 25.54
- Type
- journal article
- Language
- en
- Open access
- green
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- Lu, M., Lawrence, D. A., Marsters, S., Acosta-Alvear, D., Kimmig, P., Mendez, A. S., Paton, A. W., Paton, J. C., Walter, P., & Ashkenazi, A. (2014). Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science. https://doi.org/10.1126/science.1254312
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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