The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Enzymatic O-Methylation of N-Acetylserotonin to Melatonin
Abstract
An enzyme, hydroxyindole-O-methyl transferase, that can transfer the methyl group of S-adenosylmethionine to the hydroxy group of N-acetylserotonin to form the hormone melatonin is described. This enzyme, which is highly localized in the pineal gland, also O-methylates serotonin.
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Citations
Cites
ISOLATION OF MELATONIN, THE PINEAL GLAND FACTOR THAT LIGHTENS MELANOCYTES1
Lerner, A. B., Case, J. D., Takahashi, Y., Lee, T. H., & Mori, W. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01543a060 · Cited by 1,758
Enzymatic O-methylation of epinephrine and other catechols
Axelrod, J., & Tomchick, R. (1958) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64731-3 · Cited by 1,283
Lerner, A. B., Case, J. D., & Heinzelman, R. V. (1959) · Journal of the American Chemical Society · doi:10.1021/ja01531a060 · Cited by 443
O-Methylation of Epinephrine and Other Catechols in vitro and in vivo
Axelrod, J. (1957) · Science · doi:10.1126/science.126.3270.400 · Cited by 358
Self-citationThe formation of adrenaline from noradrenaline
Kirshner, N., & Goodall, M. (1957) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(57)90271-8 · Cited by 191
Lerner, A. B., Case, J. D., Mori, W., & Wright, M. R. (1959) · Nature · doi:10.1038/1831821a0 · Cited by 146
Enzymatic N-Methylation of Histamine
Brown, D. D., Axelrod, J., & Tomchick, R. (1959) · Nature · doi:10.1038/183680a0 · Cited by 48
Self-citation
Cited by
Brzezinski, A. (1997) · New England Journal of Medicine · doi:10.1056/nejm199701163360306 · Cited by 1,549
Melatonin: Pharmacology, Functions and Therapeutic Benefits
Tordjman, S., Chokron, S., Delorme, R., Charrier, A., Bellissant, E., Jaafari, N., & Fougerou, C. (2017) · Current Neuropharmacology · doi:10.2174/1570159x14666161228122115 · Cited by 834
Simonneaux, V., & Ribelayga, C. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.2.2 · Cited by 740
Melatonin Synthesis and Function: Evolutionary History in Animals and Plants
Zhao, D., Yu, Y., Shen, Y., Liu, Q., Zhao, Z., Sharma, R., & Reiter, R. J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00249 · Cited by 689
A Review of the Multiple Actions of Melatonin on the Immune System
Carrillo-Vico, A., Guerrero, J. M., Lardone, P. J., & Reiter, R. J. (2005) · Endocrine · doi:10.1385/endo:27:2:189 · Cited by 666
Metadata
- Authors
- Axelrod, J., & Weissbach, H.
- Venue
- Science
- Published
- 1960-04-29
- Volume
- 131
- Issue
- 3409
- Pages
- 1312-1312
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1969888297
- Cited by
- 437
- References
- 7
- FWCI
- 10.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Axelrod, J., & Weissbach, H. (1960). Enzymatic O-Methylation of N-Acetylserotonin to Melatonin. Science. https://doi.org/10.1126/science.131.3409.1312
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
