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Cited by 275

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Multistep Carcinogenesis: a 1992 Perspective

Sugimura, Takashi·1992·Science

Abstract

Cancer is the leading cause of death in Japan. Recent changes in cancer incidence patterns may reflect the trend toward a more Western diet and life-style. Among the dietary factors that contribute to carcinogenesis are the heterocyclic amines, a group of mutagenic compounds present in cooked meat and fish. Carcinogenesis is a multistep process in which cells accumulate multiple genetic alterations as they progress to a more malignant phenotype. Recognition of the growing number of interacting factors that contribute to carcinogenesis may force reconsideration of current methods of risk assessment.

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Metadata

Authors
Sugimura, T.
Venue
Science
Published
1992-10-23
Volume
258
Issue
5082
Pages
603-607
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1982928787
Cited by
275
References
52
FWCI
7.34
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Multistep Carcinogenesis: a 1992 Perspective. https://app.cochat.ai/papers/10.1126/science.1411570
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Sugimura, T. (1992). Multistep Carcinogenesis: a 1992 Perspective. Science. https://doi.org/10.1126/science.1411570

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.