The DOI matches its Crossref record.
Renal Adenyl Cyclase: Anatomically Separate Sites for Parathyroid Hormone and Vasopressin
Abstract
Adenyl cyclase from plasma membrane fractions of rat renal cortex or medulla was assayed by measuring conversion of adenosine triphosphate labeled at the α-phosphate with 32 P to cyclic 3′,5′-adenosine monophosphate labeled with 32 P. Parathyroid hormone activated the enzyme primarily in cortex; vasopressin acted primarily in medulla. These experiments support the conclusion that cyclic adenosine monophosphate mediates the action of parathyroid hormone on the kidney and show that parathyroid hormone and vasopressin stimulate adenyl cyclase at anatomically separable areas within the kidney.
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Cited by
A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide
Jüppner, H., Abou-Samra, A.-B., Freeman, M., Kong, X. F., Schipani, E., Richards, J., Kolakowski, L. F., Hock, J., Potts, J. T., Kronenberg, H. M., et al. (1991) · Science · doi:10.1126/science.1658941 · Cited by 1,249
Receptor-effector coupling by G proteins
Birnbaumer, L., Abramowitz, J., & Brown, A. M. (1990) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(90)90007-y · Cited by 1,118
Molecular cloning and expression of a rat Via arginine vasopressin receptor
Morel, A., O'Carroll, A.-M., Brownstein, M. J., & Lolaft, S. J. (1992) · Nature · doi:10.1038/356523a0 · Cited by 477
Pseudohypoparathyroidism: defective excretion of 3′,5′-AMP in response to parathyroid hormone
Chase, L. R., Melson, G. L., & Aurbach, G. D. (1969) · Journal of Clinical Investigation · doi:10.1172/jci106149 · Cited by 477
Self-citationBirnbaumer, L., & Rodbell, M. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83396-8 · Cited by 354
Metadata
- Authors
- Chase, L. R., & Aurbach, G. D.
- Venue
- Science
- Published
- 1968-02-02
- Volume
- 159
- Issue
- 3814
- Pages
- 545-547
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2055383210
- Cited by
- 397
- References
- 0
- FWCI
- 56.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chase, L. R., & Aurbach, G. D. (1968). Renal Adenyl Cyclase: Anatomically Separate Sites for Parathyroid Hormone and Vasopressin. Science. https://doi.org/10.1126/science.159.3814.545
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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